細野治 (Osamu Hosono) - マイポータル

基本情報

所属: 東京大学医科学研究所附属病院アレルギー免疫科准教授

学位: 医学博士(慶應義塾大学)

J-GLOBAL ID: 200901027318957022
researchmap会員ID: 1000201725

研究キーワード

研究分野

経歴

1986年 - 1995年

埼玉医科大学助手
1986年 - 1995年

Saitama Medical School, Research Assistant

学歴

委員歴

2003年

日本リウマチ学会, 評議員
1995年

日本臨床免疫学会, 評議員

MISC

SHP-2 inhibits tyrosine phosphorylation of Cas-L and regulates cell migration

Koji Yo, Satoshi Iwata, Yutaka Hashizume, Shunsuke Kondo, Sayaka Nomura, Osamu Hosono, Hiroshi Kawasaki, Hirotoshi Tanaka, Nam H. Dang, Chikao Morimoto

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 382(1) 210-214 2009年4月
An adult case of Henoch-Schönlein purpura complicating common peroneal nerve mononeuropathy

Ohnuma K, Hosono O, Kawasaki H, Yoshikawa N, Katayose T, Oyaizu N, Tanaka H, Morimoto C

Mod Rheumatol 19(1) 73-79 2009年2月
An adult case of Henoch-Schonlein purpura complicating common peroneal nerve mononeuropathy

Kei Ohnuma, Osamu Hosono, Hiroshi Kawasaki, Noritada Yoshikawa, Tomoki Katayose, Naoki Oyaizu, Hirotoshi Tanaka, Chikao Morimoto

MODERN RHEUMATOLOGY 19(1) 73-79 2009年2月
Role of the hinge region of glucocorticoid receptor for HEXIM1-mediated transcriptional repression

Noritada Yoshikawa, Noriaki Shimizu, Motoaki Sano, Kei Ohnuma, Satoshi Iwata, Osamu Hosono, Keiichi Fukuda, Chikao Morimoto, Hirotoshi Tanaka

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 371(1) 44-49 2008年6月
SSA/Ro52 autoantigen interacts with Dcp2 to enhance its decapping activity

Tadanori Yamochi, Kei Ohnuma, Osamu Hosono, Hirotoshi Tanaka, Yoshiyuki Kanai, Chikao Morimoto

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 370(1) 195-199 2008年5月
Role of CD26/dipeptidyl peptidase IV in human T cell activation and function

Kei Ohnuma, Nozomu Takahashi, Tadanori Yamochi, Osamu Hosono, Nam H. Dang, Chikao Morimoto

FRONTIERS IN BIOSCIENCE-LANDMARK 13 2299-2310 2008年1月
Humanized anti-CD26 monoclonal antibody as a treatment for malignant mesothelioma tumors

Teruo Inamoto, Taketo Yamada, Kei Ohnuma, Shinichiro Kina, Nozomu Takahashi, Tadanori Yamochi, Sakiko Inamoto, Yoji Katsuoka, Osamu Hosono, Hirotoshi Tanaka …

CLINICAL CANCER RESEARCH 13(14) 4191-4200 2007年7月
Transcriptional up-regulation of inhibitory PAS domain protein gene expression by hypoxia-inducible factor 1 (HIF-1) - A negative feedback regulatory circuit in HIF-1-mediated signaling in hypoxic cells

Yuichi Makino, Rie Uenishi, Kensaku Okamoto, Tsubasa Isoe, Osamu Hosono, Hirotoshi Tanaka, Arvydas Kanopka, Lorenz Poellinger, Masakazu Haneda, Chikao Morimoto

JOURNAL OF BIOLOGICAL CHEMISTRY 282(19) 14073-14082 2007年5月
Caveolin-1 triggers T-cell activation via CD26 in association with CARMA1

Kei Ohnuma, Masahiko Uchiyama, Tadanori Yamochi, Kunika Nishibashi, Osamu Hosono, Nozomu Takahashi, Shinichiro Kina, Hirotoshi Tanaka, Xin Lin, Nam H. Dang …

JOURNAL OF BIOLOGICAL CHEMISTRY 282(13) 10117-10131 2007年3月
Crk-associated substrate lymphocyte type regulates transforming growth factor-beta signaling by inhibiting Smad6 and Smad7

S. Inamoto, S. Iwata, T. Inamoto, S. Nomura, T. Sasaki, Y. Urasaki, O. Hosono, H. Kawasaki, H. Tanaka, N. H. Dang …

ONCOGENE 26(6) 893-904 2007年2月
T-cell activation via CD26 and caveolin-1 in rheumatoid synovium

Kei Ohnuma, Hiroshi Inoue, Masahiko Uchiyama, Tadanori Yamochi, Osamu Hosono, Nam H. Dang, Chikao Morimoto

Modern Rheumatology 16(1) 3-13 2006年2月
CD26 mediates dissociation of Tollip and IRAK-1 from caveolin-1 and induces upregulation of CD86 on antigen-presenting cells（共著）

OHNUMA Kei, YAMOCHI Tadanori, YAMOCHI Tadanori, UCHIYAMA Masahiko, NISHIBASHI Kunika, IWATA Satoshi, HOSONO Osamu, KAWASAKI Hiroshi, TANAKA Hirotoshi, DANG Nam H …

Mol Cell Biol 25(17) 7743-7757 2005年9月
CD26 mediates dissociation of Tollip and IRAK-1 from caveolin-1 and induces upregulation of CD86 on antigen-presenting cells

K Ohnuma, T Yamochi, M Uchiyama, K Nishibashi, S Iwata, O Hosono, H Kawasaki, H Tanaka, NH Dang, C Morimoto

MOLECULAR AND CELLULAR BIOLOGY 25(17) 7743-7757 2005年9月
HTLV-I Tax induces and associates with Crk-associated substrate lymphocyte type (Cas-L)（共著）

Oncogene. 24(7) 1262-71 2005年
CD26 T cells in the pathogenesis of asthma（共著）

Clin Exp Immunol 139(1) 13-6 2005年
Roxithromycin specifically inhibits development of collagen induced arthritis and production of proinflammatory cytokines by human T cells and macrophages（共著）

J Rheumatol 32(9) 1765-74 2005年
HTLV-I Tax induces and associates with Crk-associated substrate lymphocyte type (Cas-L)（共著）

Oncogene. 24(7) 1262-71 2005年
CD26 T cells in the pathogenesis of asthma（共著）

Clin Exp Immunol 139(1) 13-6 2005年
Roxithromycin specifically inhibits development of collagen induced arthritis and production of proinflammatory cytokines by human T cells and macrophages（共著）

J Rheumatol 32(9) 1765-74 2005年
The tetraspanin CD9 is preferentially expressed on the human CD4(+)CD45RA+ naive T cell population and is involved in T cell activation（共著）

Clinical & Experimental Immunology 137(1) 101-108 2004年7月

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細野治

基本情報

研究キーワード

研究分野

経歴

学歴

委員歴

MISC

所属学協会

共同研究・競争的資金等の研究課題

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