J-GLOBAL         Last updated: Sep 27, 2019 at 03:57
Kanazawa Medical University
Medical Research Institute
Doctor of Pharmacy

Research Interests



Division of Pharmaceutical Sciences, Graduate School, Kanazawa University
Faculty of Pharmaceutical Science, Kanazawa University

Awards & Honors

Aug 2012
Nov 2010
日本消化器癌発生学会 学会賞
Nov 2010
日本消化器癌発生学会 学会賞
May 2010
Aug 2012
Ionic liquid enables simple and rapid sample preparation of human culturing cells for scanning electron microscope analysis, Microscopy research and technique. 74:415-420, 2010

Published Papers

Yumi.Sunatani, Radhika Pankaj Kamdar, Mukesh Kumar Sharma, Tadashi.Matsui, Ryo.Sakasai, Mitsumasa.Hashimoto, Yasuhito.Ishigaki, Yoshihisa.Matsumoto, Kuniyoshi.Iwabuchi
362(2) 450   Jan 2018   [Refereed]
Protective effects of peroxiredoxin 4 (PRDX4) on cholestatic liver injury.
Zhang J, Guo X, Hamada T, Yokoyama S, Nakamura Y, Zheng J, Kurose N, Ishigaki Y, Uramoto H, Tanimoto A, Yamada S
Int J Mol Sci   19 2509   2018   [Refereed]
Translational control of SOX9 RNA by mTORC1 contributes to skeletogenesis.
Iezaki T, Horie T, Fukasawa K, Kitabatake M, Nakamura Y, Park G, Onishi Y, Ozaki K, Kanayama T, Hiraiwa M, Kitaguchi Y, Kaneda K, Manabe T, Ishigaki Y, Ohno M, Hinoi E
Stem Cell Reports   11 228-241   2018   [Refereed]
C-terminal short arginine/serine repeat sequence-dependent regulation of Y14 (RBM8A) localization.
Takanori Tatsuno, ISHIGAKI Yasuhito
Scientific Reports   8 612   2018   [Refereed]
Tropomyosin 2 heterozygous knockout in mice using CRISPR-Cas9 system displays the inhibition of injury-induced epithelial-mesenchymal transition, and lens opacity.
5. Shibata T, Shibata S, Ishigaki Y, Kiyokawa E, Ikawa M, Singh DP, Sasaki H, Kubo E
Mech Ageing Dev   171 24-30   2018   [Refereed]
Upregulation of multiple signaling pathways by Dock5 deletion in epithelial cells
Xiaohe Xu, Hisayoshi Yoshizaki, Yasuhito Ishigaki, Eri Kubo, Hiroshi Minato, Etsuko Kiyokawa
Molecular Vision   23 1081-1092   Dec 2017   [Refereed]
Effect of Collagen Tripeptide on Atherosclerosis in Healthy Humans
Naohisa Tomosugi, Shoko Yamamoto, Masayoshi Takeuchi, Hideto Yonekura, Yasuhito Ishigaki, Noriaki Numata, Shogo Katsuda, Yasuo Sakai
Journal of Atherosclerosis and Thrombosis   24(5) 530-538   May 2017   [Refereed]
JunB regulates angiogenesis and neurovascular parallel alignment in mouse embryonic skin
Jonal of Cell Science   130(5) 916-926   Jan 2017   [Refereed]
High FDG uptake on PET is associated with negative cell-to-cell adhesion molecule E-cadherin expression in lung adenocarcinoma.
(Kotaro.Higashi), Yoshimichi.Ueda, Miyako.Shimasaki, Yasuhito.Ishigaki , Yuka.Nakamura, Managu.Oguchi, Tsutomu.Takegami, Naoto.Watanabe.
Annals of nuclear medicine   31 590-595   2017   [Refereed]
Regulation of soluble Flt-1(VEGFR-1) production by hnRNP D and protein arginine methylation
T.Ikeda, Y.Yoshitomi, H.Saito, T.Shimasaki, H.Yamaya, T.Kobata, Y.Ishigaki, N.Tomosugi, Y.Yoshitake, H.Yonekura
Molecular and Cellular Biochemistry   413(1-2) 155-164   2016   [Refereed]
Scanning electron microscopy observation with ionic liquid
Y.Nakmaura, T.Tatsuno, Y.Ishigaki
Journal of Kanazawa Medical University   40(2,3) 125-130   Dec 2015
Y.Li, K.Tanaka, L.Wang, Y.Ishigaki, N.Kato
237(4) 329-338   Nov 2015
Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is now widely recognized and the patients with this disease show prominent psychiatric symptoms followed by seizures, respiratory failure, involuntary movement, autonomic instability, and amn...
Comparative genomics of the mucoid and nonmucoid strains of streptococcus pyogenes, isolated from the same patient with streptococcal meningitis
(H.Yoshida), Y.Ishigaki, A.Takizawa, K.Moro, Y.Kishi, T.Takahashi, H.Matsui
3(2) e00221-15-e00221-15   Apr 2015
53(4) 258-260   Apr 2015
Expression of hyaluronidase-4 in a rat spinal cord hemisection model
Y.Tachi, T.Okuda, N.Kawahara, N.Kato, Y.Ishigaki, T.Matsumoto
Asian Spine Journal   9(1) 7-13   Feb 2015   [Refereed]
Case report of new building works adjacent to RI facility
M.Taniguchi, Y.Ishigaki
13:177-180    Nov 2014
Reprogramming suppresses premature senescence phenotypes of Werner syndrome cells and maintains chromosomal stability over long-term culture.
(A.Shimamoto), H.Kagawa, K.Zensho, Y.Sera, Y.Kazuki, M.Osaki, M.Oshimura, Y.Ishigaki, K.Hirashima, Y.Kodama, S.Yuasa, K.Fukuda, K.Hirashima, H.Seimiya, H.Koyama, T.Shimizu, M.Takemoto, K.Yokote, M.Goto, H.Tahara
PloS one   9:e112900;1-13    Nov 2014
Global gene expression analysis with DNA microarray
Y.Ishigaki, T.Tatsuno, Y.Nakamura
39:35-41    Oct 2014
Immunostaining and time-lapse analysis of vinblastine-induced paracrystal formation in human A549 cells.
Y.Nakamura, Y.Ishigaki
Oncology letters   8:2387-2392    Sep 2014
Linagliptin-mediated DPP-4 inhibition ameliorates kidney fibrosis in streptozotocin-induced diabetic mice by inhibiting endothelial-to-mesenchymal transition in a therapeutic regimen
K.Kanasaki, S.Shi, M.Kanasaki, J.He, T.Nagai, Y.Nakamura, Y.Ishigaki, M.Kitada, SP.Srivastava, D.Koya
Diabetes.   63:2120-2131    Jun 2014
Observation of localization and structure of RNA-protein complexes using light and electron microscopy
Y.Ishigaki, Y.Nakamura, T.Tatsuno
28:1-5    May 2014
N-acetyl-seryl-aspartyl-lysyl-proline inhibits diabetes-associated kidney fibrosis and endothelial-mesenchymal transition
T.Nagai, M.Kanasaki, SP.Srivastava, Y.Nakamura, Y.Ishigaki, M.Kitada, S.Shi, K.Kanasaki, D.Koya
BioMed research international [electronic resource]   2014:696475;1-12    Mar 2014
Proteasome inhibitors and knockdown of SMG1 cause accumulation of Upf1 and Upf2 in human cells.
X.Zhao, A.Nogawa, T.Matsunaga, T.Takegami, H.Nakagawa, Y.Ishigaki
International journal of oncology   44:222-228    Jan 2014
Inhibition of mTORC2 but not mTORC1 up-regulates E-cadherin expression and inhibits cell motility by blocking HIF-2α expression in human renal cell carcinoma.
(S.Maru), Y.Ishigaki, N.Shinohara, T.Takata, N.Tomosugi, K.Nonomura
The Journal of urology.   189:1921-1929.    May 2013
SEM-EDX Elemental content maps of organisms in radioac-tive environmental pollution by FDNPP accident in 2011.
(K.Tazaki), T.Takehara, Y.Ishigaki, H.Nakagawa, N.Nemoto, A.Yokoyama, H.Kimura
16:7-24    Mar 2013
Aberrant glycogen synthase kinase 3β is involved in pancreatic cancer cell invasion and resistance to therapy.
(A.Kitano), T.Shimasaki, Y.Chikano, M.Nakada, M.Hirose, T.Higashi, Y.Ishigaki, Y.Endo, T.Takino, H.Sato, Y.Sai, K.Miyamoto, Y.Motoo, K.Kawakami, T.Minamoto
PloS one   8:e55289;1-12    Feb 2013
Meaning of tumor protein 53-induced nuclear protein 1 in the molecular mechanism of gemcitabine sensitivity.
N.Nakaya, Y.Ishigaki, H.Nakajima, M.Murakami, T.Shimasaki, T.Takata, M.Ozaki, NJ.Dusetti, JL.Iovanna, Y.Motoo
Molecular and clinical oncology.   1:100-104    Jan 2013
Chk1-mediated phosphorylation of receptor-associated late transducer at serine 250 increases its stability by stimulating its interaction with 14-3-3.
K.Takeda, T.Takata, Y.Kawai, Y.Ishigaki, K.Kajinami
Genes to cells : devoted to molecular & cellular mechanisms   18:369-386    2013
Depletion of RNA-binding protein RBM8A (Y14) causes cell cycle deficiency and apoptosis in human cells.
Y.Ishigaki, Y.Nakamura, T.Tatsuno, M.Hashimoto, T.Shimasaki, K.Iwabuchi, N.Tomosugi
Experimental biology and medicine (Maywood, N.J.)   238:889-897    2013
Effect of porcine placental extract on collagen production in human skin fibroblasts In Vitro
(C.Yoshikawa), F.Takano, Y.Ishigaki, M.Okada, S.Kyo, N,Suzuki, K.Sugiura, K.Koike
Gynecology & obstetrics : current research. [electronic resource]   3:1000186;1-4    2013
RNA-binding protein RBM8A (Y14) and MAGOH localize to centrosome in human A549 cells.
Y.Ishigaki, Y.Nakamura, T.Tatsuno, M.Hashimoto, K.Iwabuchi, N.Tomosugi
Histochemistry and cell biology.   141:101-109    2013
Distribution of Sr,Cs,Np,and Pu in radioactive polluted paddy soils and organisms.
(K.Tazaki), T.Takehara, Y.Ishigaki, H.Nakagawa
46:35-57    2013
56:14-18    2013
Characterization of proteins secreted by pancreatic cancer cells with anticancer drug treatment in vitro
T.Takata, Y.Ishigaki, T.Shimasaki, H.Tsuchida, Y.Motoo, A.Hayashi, N.Tomosugi
Oncology reports.   28:1968-1976    Dec 2012
Use of ionic liquid in fungal taxonomic study of ultrastructure of basidiospore ornamentation
(K.Yanaga), N.Maekawa, N.Shimomura, Y.Ishigaki, Y.Nakamura, T.Takegami, N.Tomosugi, S.Miyazawa, S.Kuwabata
Mycological Progress   11:343-347    Nov 2012
Expression pattern of Galectin 4 in rat placentation
T.Arikawa, E.Shimamura, H.Shimada, N.Nishi, T.Tatsuno, Y.Ishigaki, N.Tomosugi, C.Yamashiro, T.Hata, T.Takegami, H.Mogami, K.Yamaguchi, T.Nakamura, H.Otani, T.Hatta, H.Shoji
Placenta   33:885-887    Aug 2012
Expression pattern of Galectin 4 in rat placentation
Tomohiro Arikawa, Eriko Simamura, Hiroki Shimada, Nozomu Nishi, Takanori Tatsuno, Yasuhito Ishigaki, Naohisa Tomosugi, Chizu Yamashiro, Toshiyuki Hata, Tsutomu Takegami, Tomonori Nakamura, Haruta Mogami, Ken Yamaguchi, Hiroki Otani, Toshihisa Hatta, Hiroki Shoji
Placenta   2012 Aug 6. [Epub ahead of pri    Aug 2012
Loss of HITS(FAM107B) expression in cancers of multiple organs: tissue microarray analysis
(H.Nakajima), K.Koizumi, T.Tanaka, Y.Ishigaki, Y.Yoshitake, H.Yonekura, T.Sakuma, T.Fukushima, H.Umehara, S.Ueno, T.Minamoto, Y.Motoo
International journal of oncology   41:1347-1357    May 2012
Observation of live ticks (Haemaphysalis flava) by scanning electron microscopy under high vacuum pressure
Y.Ishigaki, Y.Nakamura, Y.Oikawa, Y.Yano, S.Kuwabata, H.Nakagawa, N.Tomosugi, T.Takegami
PloS one   7:e32676 1-6    Mar 2012
Garlic extract and its selected organosulphur constituents promote ileal immune responses ex vivo.
(N Ota), F Takano, S Muroga, T Kawabata, Y.Ishigaki, N Yahagi, T Ohta
Journal of functional foods   4:243-252    Jan 2012
A novel clinical entity, IgG4-related disease (IgG4RD): general concept and details
H.Umehara, K.Okazaki, Y.Masaki, M.Kawano, M.Yamamoto, T.Saeki, S.Matsui, T.Sumida, T.Mimori, Y.Tanaka, K.Tsubota, T.Yoshino, S.Kawa, R.Suzuki, T.Takegami, N.Tomosugi, N.Kurose, Y.Ishigaki, A.Azumi, M.Kojima, S.Nakamura, D.Inoue
Modern rheumatology / the Japan Rheumatism Association.   22:1-14    2012
Comparative study of hydrophilic and hydrophobic ionic liquids for observing cultured human cells by scanning electron microscopy.
Y.Ishigaki, Y.Nakamura, T.Takehara, T.Kurihara, H.Koga, T.Takegami, H.Nakagawa, N.Nemoto, N.Tomosugi, S.Kuwabata, S.Miyazawa
Microscopy research and technique   74:1104-1108    Dec 2011
Role of amino acid transporter LAT2 in the activation of mTORC1 pathway and the pathogenesis of crescentic glomerulonephritis
(R.Kurayama), N.Ito, Y.Nishibori, D.Fukuhara, Y.Akimoto, E.Higashihara, Y.Ishigaki, Y.Sai, K.Miyamoto, H.Endou, Y.Kanai, K.Yan
Laboratory investigation; a journal of technical methods and pathology.   91:992-1006    Jul 2011
Hypoxia down-regulates sFlt-1 (sVEGFR-1) expression in human microvascular endothelial cells by a mechanism involving mRNA alternative processing
T.Ikeda, L.Sun, N.Tsuruoka, Y.Ishigaki, Y.Yoshitomi, Y.Yoshitake, H.Yonekura
The Biochemical journal.   436:399-407    Jun 2011
VEGF-A and its isoform VEGF121 mRNA expression measured by quantitative real-time RT-PCR: correlation with F-18 FDG uptake and aggressiveness of lung adenocarcinoma: preliminary study
(J.F.Guo), K.Higashi, Y.Ueda, Y.Ishigaki, T.Sakuma, M.Oguchi, T.Takegami, Y.Ohta, L.Zhang, K.Xu, H.Nishida, H.Tonami
Annals of nuclear medicine.   25:29-36    May 2011
Resveratrol improves hippocampal atrophy in chronic fatigue mice by enhancing neurogenesis and inhibiting apoptosis of granular cells
J.Moriya, R.Chen, J.Yamakawa, K.Sasaki, Y.Ishigaki, T.Takahashi
Biological & pharmaceutical bulletin   34:354-359    Mar 2011
Comprehensive analysis of alternative splicing and functionality in neuronal differentiation of P19 cells.
(H.Suzuki), K.Ozaki, K.Sano, A.H.M.Khurshid Alam, Y.Nakamura, Y.Ishigaki, K.Kawahara, T.Tsukahara
PloS one   6:e16880,1-11    Feb 2011
Inhibitory effects of statins on cytomegalovirus production in human cells: comprehensive analysis of gene expression profiles
(T.Murayama), C.Bi, Y.Li, Y.Ishigaki, F.Takano, T.Takegami, T.Ohta, H.Sumino, K.Ubukata, T.Takahashi
Journal of experimental and clinical medicine   3:40-45    Feb 2011
Human SMG-1 is involved in gemcitabine-induced primary microRNA-155/BIC up-regulation in human pancreatic cancer PANC-1 cells
(QS.Xia), Y.Ishigaki, X.Zhao, T.Shimasaki, H.Nakajima, H.Nakagawa, T.Takegami, ZH.Chen, Y.Motoo
Pancreas.   40:55-60    Jan 2011
Metabolic disorder, inflammation, and deregulated molecular pathways converging in pancreatic cancer development: Implications for new therapeutic strategies
Y.Motoo, T.Shimasaki, Y.Ishigaki, H.Nakajima, K.Kawakami, T.Minamoto
Cancers   3:446-460    Jan 2011
Ultraviolet B-induced expression of amphiregulin and growth differentiation factor 15 in human lens epithelial cells
H.Osada, Y.Yoshitake, T.Ikeda, Y.Ishigaki, T.Takata, N.Tomosugi, H.Sasaki, H.Yonekura
Molecular vision   17:159-169    Jan 2011
Scanning electron microscopy with an ionic liquid reveals the loss of mitotic protrusions of cells during the epithelial-mesenchymal transition
Y.Ishigaki, Y.Nakamura, T.Takehara, T.Shimasaki, T.Tatsuno, F.Takano, Y.Ueda, Y.Motoo, T.Takegami, H.Nakagawa, S.Kuwabata, N.Nemoto, N.Tomosugi, S.Miyazawa
Microscopy research and technique   74:1024-1031    2011
Ultrastructural localization of Upf2 and its binding to mRNA molecules in human cells
Y.Ishigaki, T.Kurihara, Y.Nakamura, X.Zhao, T.Takata, S.Izumi, T.Takegami, N.Tomosugi, H.Nakagawa
24:8-13    Nov 2010
Ionic liquid enables simple and rapid sample preparation of human culturing cells for scanning electron microscope analysis
Y.Ishigaki, Y.Nakamura, T.Takehara, N.Nemoto, T.Kurihara, H.Koga, H.Nakagawa, T.Takegami, N.Tomosugi, S.Miyazawa, S.Kuwabata
Microscopy research and technique   74:415-420    Sep 2010
Carotenoids modulate cytokine production in Peyer's patch cells ex vivo.
(M.Yamaguchi), I.Hasegawa, N.Yahagi, Y.Ishigaki, F.Takano, T.Ohta
Journal of agricultural and food chemistry   58:8566-8572    Aug 2010
Aquaporin as a novel player in cancer cell the invasion of cancer cells
Y.Ueda, M.Shimasaki, Y.Machida, Y.Takahara, Y.Himi, Y.Ishigaki, K.Sato, T.Sakuma, H.Toga, S.Kawakami, S.Katsuda
35:55-60    Aug 2010
Gene expression profiling in rat pancreas after ventromedial hypothalamic lesioning.
(T.Kiba), Y.Kintaka, Y.Suzuki, N.Ishizuka, Y.Ishigaki, S.Inoue
Pancreas.   39:627-632    Jul 2010
Assessment of VEGF-D expression measured by immunohistochemical staining and F-18 FDG uptake on PET as biological prognostic factors for recurrence in patients with surgically resected lung adenocarcinoma
L.Zhang, K.Higashi, Y.Ishigaki, Y.Ueda, T.Sakuma, T.Takegami, M.Oguchi, K.Xu, Y.Ohta, H.Nishida, H.Tonami
Annals of nuclear medicine.   24:533-540    May 2010
VMH lesions downregulate the expression of Per2 gene in the pancreas in the rat.
(T.Kiba), Y.Kintaka, Y.Suzuki, N.Ishizuka, Y.Ishigaki, S.Inoue
Neuroscience letters.   471:148-151    May 2010
90:123-127    Jan 2010
Application of molecular medicine to pancreatic cancer
T.Shimasaki, Y.Ishigaki, T.Minamoto, Y.Motoo
25:35-45    Jan 2010
Induction of HITS, a newly identified family with sequence similarity 107 protein (FAM107B), in cancer cells by heat shock stimulation
H.Nakajima, Y.Ishigaki, QI-S.Xia, T.Ikeda, Y.Yoshitake, H.Yonekura, T.Nojima, T.Tanaka, H.Umehara, N.Tomosugi, T.Takata, T.Shimasaki, N.Nakaya, I.Sato, K.Kawakami, K.Koizumi, T.Minamoto, Y.Motoo
International journal of oncology   37:583-593    2010
Molecular analysis on responses of TP53INP1-knockout mouse embryonic fibroblasts to anti-cancer agents
(Q.Bian), Y.Motoo, H.Nakajima, T.Shimasaki, Y.Ishigaki
125-128    2010
An emerging strategy for cancer treatment targeting aberrant glycogen synthase kinase 3beta.
(K.Miyashita), M.Nakada, K.Shakoori, Y.Ishigaki, T.Shimasaki, Y.Motoo, Kawakami K, T.Minamoto
Anti-cancer agents in medicinal chemistry   9:1114-1122    Dec 2009
Introduction of OLS inNIBB
Y.Ishigaki, T.Takata, N.Tomosugi, T.Takegami, H.Nakagawa
8:15-18    Dec 2009
Gene Expression Profiling in Rat Liver After VMH Lesioning.
(T.Kiba), Y.Kintaka, Y.Suzuki, E.Nakata, Y.Ishigaki, S.Inoue
Experimental biology and medicine (Maywood, N.J.)   234:758-763    Jul 2009
26:681    Jun 2009
Ventromedial hypothalamic lesions change the expression of neuron-related genes and immune-related genes in rat liver.
(T.Kiba), Y.Kintaka, Y.Suzuki, E.Nakata, Y.Ishigaki, S.Inoue
Neuroscience letters.   455:14-16    May 2009
Isolation of N-acetylneuraminic acid and N-glycolylneuraminic acid from Pleurocybella porrigens.
T.Takata, T.Hasegawa, T.Tatsuno, J.Date, Y.Ishigaki, Y.Nakamura, N.Tomosugi, F.Takano, T.Ohta
Journal of health science (Tokyo, Japan)   55:373-379    Mar 2009
Changes of neuron-specific and apoptosis gene expression levels after ventromedial hypothalamic lesions in rat intestine
(T.Kiba), Y.Kintaka, Y.Suzuki, E.Nakata, T.Osaka, Y.Ishigaki, S.Inoue
Experimental biology and medicine (Maywood, N.J.)   233:1368-1373    Dec 2008
The Kampo Medicines Orengedokuto, Bofutsuhosan and Boiogito Have Different Activities to Regulate Gene expressions in differentiated Rat White Adipocytes : Comprehensive Analysis of Genetic Profiles
J.Yamakawa, Y.Ishigaki, F. Takano, T. Takahashi, J. Yoshida, J.Moriya, T.Takata, T. Tatsuno, K. Sasaki, T. Ohta, T.Takegami, F. Yoshizaki
Biological & pharmaceutical bulletin   31: 2083-2089    Nov 2008
The kampo medicines orengedokuto, bofutsushosan and boiogito have different activities to regulate gene expressions in differentiated rat white adipocytes: comprehensive analysis of genetic profiles
J.Yamakawa, Y.Ishigaki, F.Takano, T.Takahashi, J.Yoshida, J.Moriya, T.Takata, T.Tatsuno, K.Sasaki, T.Ohta, T.Takegami, F.Yoshizaki
Biological & pharmaceutical bulletin   31:2083-2089    Nov 2008
Bioreductive activation of quinone antitumor drugs by mitochondrial voltage-dependent anion channel 1
E.Simamura, H.Shimada, Y.Ishigaki, T.Hatta, N.Higashi, K-I.Hirai
Anatomical science international / Japanese Association of Anatomists   83:261-266    Aug 2008
The Liquid Culture of Entomogenous fungus Paecilomyces tenuipes and Its Glycoprotein Costituent Protects against Anemia in Mice Treated with 5-fluorouracil.
T. Takata, T. Tanaka, N. Yahagi, R. Yahagi, H. Tsuchida, Y.Ishigaki, N.Tomosugi, S. Fushiya, F. Takano, T. Ohta
Biological & pharmaceutical bulletin   31 : 1561-1573    Aug 2008
The liquid culture filtrates of entomogenous fungus Paecilomyces tenuipes and its glycoprotein constituent protects against anemia in mice treated with 5-fluorouracil
(T.Takata), T.Taanaka, N.Yahagi, R.Yahagi, H.Tsuchida, Y.Ishigaki, N.Tomosugi, S.Fushiya, F.Takano, T. Ohta
Biological & pharmaceutical bulletin   31:1565-1573    Aug 2008
Copmparative study of chromosomal analysis using SNPs genotyping arrays and G-banding in MCA/MR(multiple congenital abnormality / mental retardation) patients
M.Ozaki, Y.Ishigaki
33:1-12    Jun 2008
Multiple shRNA expressions in a single plasmid vector improve RNAi against the XPA gene
(A.Nagao), X.Zhao, T.Takegami, H.Nakagawa, S.Matsui, T.Matsunaga, Y.Ishigaki
Biochemical and biophysical research communications   370:301-305    2008
High-quality RNA extraction from rat pancreas for microarray analysis
(Kiba T), Y.Kintaka, E.Nakada, Y.Suzuki, S.Inoue, Y.Ishigaki
Pancreas.   35:98-100    Jul 2007
Apoptosis-related gene expression profile is changed by gemcitabine in pancreatic cancer cell line(PANC-1)
T.Shimasaki, Y.Ishigaki, T.Minato, Y.Motoo
22:14-20    Mar 2007
30:320-325    Dec 2005
7    Dec 2005
UV-B protective effect of a polyacylated anthocyanin, HBA, in flower petals of the blue morning glory, Ipomoea tricolor cv. Heavenly Blue.
Bioorg Med Chem   13:2015-2020    2005
Human NTH1 physically interacts with p53 and proliferating cell nuclear antigen.
Biochem. Biophys. Res. Commun.      2004
A case withcongenital photosensitivity,hairloss, growth failure and pulmonary stenosis relation with Rothmund-Thomson synderome.
Clin. Pediatr. Endocrinology      2003
Photodegradation of 4-alkylphenols using BiO4 photocatalyst under irradiation with visible light from a solar simulator.
Applied Catalysis B: Environmental      2003
cDNA cloning of the chiken DDB1 gene encoding the p127 subunit of damaged DNA-binding protein
An ultraviolet-B-resistant mutant with enhanced DNA repair in Arabidopsis.
Plant physiology      2002
Photocatalytic degradation of 4-n-Nonylphenol under irradiation from solar simulator: Comparison between BiVO4 and TiO2 photocatalysts.
Chem. Lett.      2002
The exon-exon junction complex is detected on CBP80-bound but not eIF4E-bound mRNA in mammalian cells: Dynamics of mRNP remodeling
(F.Lejeune), Y.Ishigaki, X.Li, L.E.Maquat
The EMBO journal.   13:3536-3545    2002
Evidence for a pioneer round of mRNA translation: mRNAs subject to nonsense-mediated decay in mammalian cells are bound by CBP80 and CBP20
Y.Ishigaki, X.Li, G.Serin, L.E.Maquat
Cell   106(5):607-617    2001
Evidence that phosphorylation of human Upfl protein
RNA      2001
Development and characterization of a DNA solar dosimeter.
A comparison of UVB-carcinogenesis between nude mice and nude beige mice
Journal of Radiation Research      1998
An UVB-carcinogenesis model with KSN nude mice.
Enhanced human tumor cell transplantability in a new congenic immunodeficient mouse; KSN-BNX.
Supranuclear melanin caps reduce ultraviolet induced DNA photoproducts in human epidermis.


16 7-24   2013
放射線汚染した水田土壌と生物におけるSr, Cs, Np, Puの分布
46 35-57   2013
Inhibitory effects of statins on cytomegalovirus production in human cells: comprehensive analysis of gene expression profiles
3 40-45   2011
Ultraviolet B-induced expression of amphiregulin and growth differentiation factor 15 in human lens epithelial cells
17 159-169   2011
Ultrastructural localization of Upf2 and its binding to mRNA molecules in human cells
24 8-13   2010
アクアポリン: がん細胞浸潤の新たなプレーヤー
35 55-60   2010
90 123-127   2010
Molecular analysis on responses of TP53INP1-knockout mouse embryonic fibroblasts to anti-cancer agents
125-128   2010
8 15-18   2009
26 681   2009
33 1-12   2008
7   2005
30 320-325   2005
Evidence that phosphorylation of human Upfl protein
Enhanced human tumor cell transplantability in a new congenic immunodeficient mouse; KSN-BNX.
New immunodeficient mouse strains bred by introducing beige and xid mutations into the KSN nude strain

Books etc

Japanese Encephalitis Virus Infection and Replication: Biological Roles of Nonstructural Protein NS4a and The 3'-Untranslated Region in Persistent Infection
T.Takegami, T.Tasaki, M.Murakami, Y.Ishigaki, M.Taniguchi, T.Nojima, S.Nukuzuma
SMGroup (USA)   Aug 2015   
Room-Temperature Ionic Liquid-Bases SEM/EDX Techniques for Biological Specimens and in situ Electrode Reaction Observation
(T.Tsuda), E.Mochizuki, S.Kishida, N.Nemoto, Y.Ishigaki, S.Kuwabata
Willy   Apr 2014   
Jun 2010   
Optimized gene silencing by co-expression of multiple shRNAs in a single vector.
Y.Ishigaki, A.Nagao, T.Matsunaga
Humana Press   May 2010   
SEM-EDX Observation of diatomaceous earth at radioactive paddy soils in Fukushima, Japan
(K.Tazaki), T.Takehara, Y.Ishigaki, H.Nakagawa, M.Okuno
Dec 2014   

Conference Activities & Talks

May 2007   
Apr 2008   
Aqueous extract of peanut coat and its main constituent procyanidin A1 suppress serum IgE and IgG1 levels in mice-immunized with ovalbumin
T.Takata, F.Takano, Y.Nakamura, Y.Ishigaki, T.Ohta
The 4th KSP-JSP-CCTNM Joint Symposium on Pharmacognosy   Jun 2008   
N-Glycoryl neuraminic acid from edible/toxic mushroom Pleurocybella porrigens
(J.Date), T.Takata, T.Tatsuno, Y.Ishigaki, F.Takano, T.Ohta
The 4th KSP-JSP-CCTCCM Joint Symposium on Pharmacognosy   Jun 2008   
N-glycory neuraminic acid from edible/toxic mushroom Pleurocybella porrigens
(J.Date), T.Takata, T.Tatsuno, Y.Ishigaki, F.Takano, T.Ohta
The 4th KSP-JSP-CCTCCM Joint Symposium on Pharmacognosy   Jun 2008   



Research Grants & Projects

Project Year: 2017 - 2019
Project Year: 2017 - 2019
Project Year: 2015 - 2016
Project Year: 2013 - 2015
Project Year: 2009 - 2011


特願2009-166663 : 抗癌剤、癌細胞のアポトーシス誘導方法、及び抗癌剤のスクリーニング方法
特願2010-194326 : IgG4関連疾患診断用マーカー及びその利用