MISC

2014年11月

Prognostic factors and effects of early surgical drainage in patients with peritonsillar abscess

JOURNAL OF INFECTION AND CHEMOTHERAPY
  • Tomoyasu Tachibana
  • ,
  • Yorihisa Orita
  • ,
  • Iku Abe-Fujisawa
  • ,
  • Yuya Ogawara
  • ,
  • Yuko Matsuyama
  • ,
  • Aiko Shimizu
  • ,
  • Michihiro Nakada
  • ,
  • Yasuharu Sato
  • ,
  • Kazunori Nishizaki

20
11
開始ページ
722
終了ページ
725
記述言語
英語
掲載種別
DOI
10.1016/j.jiac.2014.07.018
出版者・発行元
SPRINGER JAPAN KK

Peritonsillar abscess is a frequently encountered otorhinolaryngological emergency, but the characteristics of patients with this disease have not been described in detail. The objective of this study was to delineate prognostic factors associated with peritonsillar abscess and the effects of early surgical drainage for the treatment of peritonsillar abscess. We conducted a retrospective analysis of the medical records of 240 consecutive patients with PTA during the period from 2007 to 2013. Univariate analysis indicated that the period between symptom onset and relief was significantly longer in patients with high levels of C-reactive protein (CRP) (>8.53 mg/dL, p = 0.0073) and without early surgical drainage of pus (p < 0.0001). Multivariate analysis identified both of these values as independently associated with longer duration of symptoms (high CRP, P < 0.0001; no early drainage, P < 0.0001). Univariate analysis indicated that the duration between symptom onset and complete recovery from the disease was significantly longer with age >= 40 years (P = 0.0004), no history of recurrent tonsillitis (P = 0.022), high CRP level (P = 0.0017), and no early surgical drainage of the abscess (P = 0.0014). Multivariate analysis identified older age (P = 0.0004), high CRP level (P = 0.0001), and no early drainage (P < 0.0001) as independently associated with longer duration between symptom onset and complete recovery. Early surgical drainage of the abscess is important for the treatment of peritonsillar abscess. Patients >40 years old with peritonsillar abscess and high CRP levels should be recognized as a high-risk group. (C) 2014, Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseases. Published by Elsevier Ltd. All rights reserved.

Web of Science ® 被引用回数 : 12

リンク情報
DOI
https://doi.org/10.1016/j.jiac.2014.07.018
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000345558200011&DestApp=WOS_CPL

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