MISC

2016年9月

Kikuchi-Fujimoto disease: evaluation of prognostic factors and analysis of pathologic findings

ACTA OTO-LARYNGOLOGICA
  • Hidenori Marunaka
  • ,
  • Yorihisa Orita
  • ,
  • Tomoyasu Tachibana
  • ,
  • Kentaro Miki
  • ,
  • Takuma Makino
  • ,
  • Yuka Gion
  • ,
  • Kazunori Nishizaki
  • ,
  • Tadashi Yoshino
  • ,
  • Yasuharu Sato

136
9
開始ページ
944
終了ページ
947
記述言語
英語
掲載種別
DOI
10.3109/00016489.2016.1164895
出版者・発行元
TAYLOR & FRANCIS LTD

Conclusion: In Kikuchi-Fujimoto disease (KFD), a low ratio of blastic cells (<70%) in lymph node specimens and absence of atypical lymphocytes in peripheral blood are predictive of a protracted clinical course. Objectives: Since KFD is a self-limiting disorder that does not require any specific management, prognostic factors have received little attention. The present study identified clinical and pathological factors that may affect the period from onset to cure of KFD. Methods: This retrospective study investigated 43 KFD patients who underwent lymph node biopsy diagnosed by immunohistochemical staining at Okayama University Hospital and Okayama Medical Center from January 2001 to December 2013. Results: Mean total period from onset to cure was 6 months (median =9.4 months; range =1-37 months). Low ratios of blastic cell proliferation area (<70%) in lymph node specimens (p=0.011) and absence of atypical lymphocytes in peripheral blood (p=0.026) were associated with a relatively long duration of KFD.


リンク情報
DOI
https://doi.org/10.3109/00016489.2016.1164895
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000382582200014&DestApp=WOS_CPL
ID情報
  • DOI : 10.3109/00016489.2016.1164895
  • ISSN : 0001-6489
  • eISSN : 1651-2251
  • Web of Science ID : WOS:000382582200014

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