1991年5月
CHANGES IN BONE AFTER HIGH-DOSE IRRADIATION - BIOMECHANICS AND HISTOMORPHOLOGY
JOURNAL OF BONE AND JOINT SURGERY-BRITISH VOLUME
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- 巻
- 73
- 号
- 3
- 開始ページ
- 492
- 終了ページ
- 497
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- 出版者・発行元
- BRITISH EDITORIAL SOC BONE JOINT SURGERY
We studied the effects of high-dose irradiation on the mechanical properties and morphology of cortical bone in rabbits for 52 weeks after a single dose of 50 Gy of electron-beam to the tibia.
After four weeks, the bending strength of the irradiated bone was unchanged, but at 12 weeks, the strength had decreased significantly. At 24 weeks after irradiation mean strength was less than half of controls but by 52 weeks there was a tendency toward recovery. Similar, synchronous changes of damage and recovery were seen in cortical porosity, haematopoietic cells in the bone marrow and endosteal new bone formation.
After four weeks, the bending strength of the irradiated bone was unchanged, but at 12 weeks, the strength had decreased significantly. At 24 weeks after irradiation mean strength was less than half of controls but by 52 weeks there was a tendency toward recovery. Similar, synchronous changes of damage and recovery were seen in cortical porosity, haematopoietic cells in the bone marrow and endosteal new bone formation.
- リンク情報
- ID情報
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- ISSN : 0301-620X
- PubMed ID : 1670456
- Web of Science ID : WOS:A1991FP41400031