A reduced kinetic model for n-heptane, i-octane, n-cetane and heptamethylnonane is developed based on that for the primary reference fuel (n-heptane and i-octane). The present model, which can be easily applied to a conventional CFD code, is constructed simply from 59 chemical species and 96 reactions. The ignition delay times are calculated by this kinetic model and compared with those by full kinetic models under high pressure and temperature conditions. The results indicate that the general trend of the ignition delay times for various temperatures and pressures is well described with this reduced model. Furthermore, the present model is combined with a commercial CFD code and used to simulate the ignition process of a diesel spray under a high pressure and temperature condition. The effect of the cetane number of the fuel on the ignition process is investigated. Copyright © 2012 SAE International.