Scores of the Todai Health Index, THI, of 404 nurses in a university hospital were compared with those of community women. Nurses showed much higher scores in the scale of?gIrregularity of daily life?hand scales related with mental complaints such as" Impulsiveness", "Mental instability", "Depressiveness", and the discriminant value of neurosis. On the other hand, scales related with physical complaints did not differ much from those of the community women, while nurses of 25 to 39 years old showed higher scores in some scales related with fatigue of total body, eye and skin, due presumably to their heavy work load. As a consequence, the aging pattern of health conditions of nurses was unique, showing no clear peak of the menopausal complaints. These findings suggest that not only physical but also mental health has been affected by their work loads, which needs to be improved.