大橋貴 (Takashi Ohashi) - マイポータル

基本情報

所属: 北海道大学遺伝子病制御研究所病態研究部門助教授・准教授

学位: 獣医学博士(東京大学)

J-GLOBAL ID: 200901012100886924
researchmap会員ID: 1000203809

外部リンク: http://www.igm.hokudai.ac.jp/molvir/Index.html

研究キーワード

研究分野

経歴

2004年 - 2007年

北海道大学助教授（遺伝子病制御研究所感染病態分野）助教授
2004年 - 2007年

Associate Professor
2007年

- 北海道大学准教授（遺伝子病制御研究所感染病態分野）准教授
1996年 - 2004年

東京医科歯科大学助手（大学院医歯学総合研究科免疫治療学分野）助手
1996年 - 2004年

Research Associate
1993年 - 1996年

アメリカ国立癌研究所 Visiting Fellow (Loboratory of Molecular Oncology) 研究員
1993年 - 1996年

Researcher,National Cancer Institute, Visiting Fellow (Loboratory of Molecular Oncology),April 1996; Tokyo Medical and Dental University, Instructor (Department of Immunotherapeutics, Graduate Schoo

学歴

論文

Effects of different promoters on the virulence and immunogenicity of a HIV-1 Env-expressing recombinant vaccinia vaccine

Mao Isshiki, Xianfeng Zhang, Hirotaka Sato, Takashi Ohashi, Makoto Inoue, Hisatoshi Shida

VACCINE 32(7) 839-845 2014年2月査読有り
Combined Cytolytic Effects of a Vaccinia Virus Encoding a Single Chain Trimer of MHC-I with a Tax-Epitope and Tax-Specific CTLs on HTLV-I-Infected Cells in a Rat Model

Takashi Ohashi, Takafumi Nakamura, Minoru Kidokoro, Xianfeng Zhang, Hisatoshi Shida

BIOMED RESEARCH INTERNATIONAL 2014 902478 2014年査読有り
Immunogenicity and safety of the vaccinia virus LC16m8Δ vector expressing SIV Gag under a strong or moderate promoter in a recombinant BCG prime-recombinant vaccinia virus boost protocol.

Sato H, Jing C, Isshiki M, Matsuo K, Kidokoro M, Takamura S, Zhang X, Ohashi T, Shida H

Vaccine 31(35) 3549-3557 2013年8月2日査読有り
Elicitation of Both Anti HIV-1 Env Humoral and Cellular Immunities by Replicating Vaccinia Prime Sendai Virus Boost Regimen and Boosting by CD40Lm

Xianfeng Zhang, Tomoyoshi Sobue, Mao Isshiki, Shun-ichi Makino, Makoto Inoue, Kazunori Kato, Tatsuo Shioda, Takashi Ohashi, Hirotaka Sato, Jun Komano …

PLOS ONE 7(12) e51633 2012年12月査読有り
Nuclear and cytoplasmic effects of human CRM1 on HIV-1 production in rat cells

Mika Nagai-Fukataki, Takashi Ohashi, Iwao Hashimoto, Tominori Kimura, Yoshiyuki Hakata, Hisatoshi Shida

GENES TO CELLS 16(2) 203-216 2011年2月査読有り
Inhibitory effect of human TRIM5 alpha on HIV-1 production

Xianfeng Zhang, Mariko Kondo, Jing Chen, Hiroyuki Miyoshi, Hajime Suzuki, Takashi Ohashi, Hisatoshi Shida

MICROBES AND INFECTION 12(10) 768-777 2010年9月査読有り
Functional analysis of Foxp3 and CTLA-4 expressing HTLV-1-infected cells in a rat model

Ryo Takayanagi, Takashi Ohashi, Hisatoshi Shida

MICROBES AND INFECTION 11(12) 964-972 2009年10月査読有り
Induction of IL-10-and IFN-gamma-producing T-cell responses by autoreactive T-cells expressing human T-cell leukemia virus type I Tax

Natsuko Takatsuka, Atsuhiko Hasegawa, Ayako Takamori, Yukiko Shimizu, Hirotomo Kato, Takashi Ohashi, Teruo Amagasa, Takao Masuda, Mari Kannagi

INTERNATIONAL IMMUNOLOGY 21(9) 1089-1100 2009年9月査読有り
Synergistic effect of human CycT1 and CRM1 on HIV-1 propagation in rat T cells and macrophages

Hiroyuki Okada, Xianfeng Zhang, Ismael Ben Fofana, Mika Nagai, Hajime Suzuki, Takashi Ohashi, Hisatoshi Shida

RETROVIROLOGY 6 43 2009年5月査読有り
Immunogenicity of newly constructed attenuated vaccinia strain LC16m8Δ that expresses SIV Gag protein

Hajime Suzuki, Minoru Kidokoro, Ismael Ben Fofana, Takashi Ohashi, Tomotaka Okamura, Kazuhiro Matsuo, Naoki Yamamoto, Hisatoshi Shida

Vaccine 27(7) 966-971 2009年2月11日査読有り
Activation and detection of HTLV-I Tax-specific CTLs by Epitope expressing Single-Chain Trimers of MHC Class I in a rat model

Takashi Ohashi, Mika Nagai, Hiroyuki Okada, Ryo Takayanagi, Hisatoshi Shida

RETROVIROLOGY 5 90 2008年10月査読有り
Enhanced replication of human T-cell leukemia virus type 1 in T cells from transgenic rats expressing human CRM1 that is regulated in a natural manner

Ryo Takayanagi, Takashi Hashi, Eizaburo Yamashita, Yohei Kurosaki, Kumiko Tanaka, Yoshiyuki Hakata, Yasumasa Komoda, Satoru Ikeda, Yasuko Tsunetsugu-Yokota, Yuetsu Tanaka …

JOURNAL OF VIROLOGY 81(11) 5908-5918 2007年6月査読有り
Erythroblast transformation by the friend spleen focus-forming virus is associated with a block in erythropoietin-induced STAT1 phosphorylation and DNA binding and correlates with high expression of the hematopoietic phosphatase SHP-1

K Nishigaki, C Hanson, T Ohashi, A Spadaccini, S Ruscetti

JOURNAL OF VIROLOGY 80(12) 5678-5685 2006年6月査読有り
Erythroblast transformation by the friend spleen focus-forming virus is associated with a block in erythropoietin-induced STAT1 phosphorylation and DNA binding and correlates with high expression of the hematopoietic phosphatase SHP-1

K Nishigaki, C Hanson, T Ohashi, A Spadaccini, S Ruscetti

JOURNAL OF VIROLOGY 80(12) 5678-5685 2006年6月
Tumor immunity against adult T-cell leukemia

M Kannagi, N Harashima, K Kurihara, T Ohashi, A Utsunomiya, R Tanosaki, M Masuda, M Tomonaga, J Okamura

CANCER SCIENCE 96(5) 249-255 2005年5月査読有り
Potential immunogenicity of adult T cell leukemia cells in vivo

K Kurihara, N Harashima, S Hanabuchi, M Masuda, A Utsunomiya, R Tanosaki, M Tomonaga, T Ohashi, A Hasegawa, T Masuda …

INTERNATIONAL JOURNAL OF CANCER 114(2) 257-267 2005年3月査読有り
Evaluation of the functional involvement of human immunodeficiency virus type 1 cDNA during integrase in nuclear import of viral acute infection

T Ikeda, H Nishitsuji, Zhou, X, N Nara, T Ohashi, M Kannagi, T Masuda

JOURNAL OF VIROLOGY 78(21) 11563-11573 2004年11月査読有り
Inhibition of human immunodeficiency virus type 1 replication by Z-100, an immunomodulator extracted from human-type tubercle bacilli, in macrophages

Y Emori, T Ikeda, T Ohashi, T Masuda, T Kurimoto, M Takei, M Kannagi

JOURNAL OF GENERAL VIROLOGY 85(9) 2603-2613 2004年9月査読有り
Inducible-costimulator-mediated suppression. of human immunodeficiency virus type 1 replication in CD4+T lymphocytes

Zhou, X, M Kubo, H Nishitsuji, K Kurihara, T Ikeda, T Ohashi, M Azuma, T Masuda, M Kannagi

VIROLOGY 325(2) 252-263 2004年8月査読有り
Immunological risks of adult T-cell leukemia at primary HTLV-I infection

M Kannagi, T Ohashi, N Harashima, S Hanabuchi, A Hasegawa

TRENDS IN MICROBIOLOGY 12(7) 346-352 2004年7月査読有り

大橋貴

基本情報

研究キーワード

研究分野

経歴

学歴

論文

MISC

所属学協会

共同研究・競争的資金等の研究課題

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