吉田幸一 (Yoshida Koichi) - マイポータル - researchmap

基本情報

所属: 札幌医科大学医療人育成センター教養教育研究部門生物学教授

学位: 医学博士
理学修士

J-GLOBAL ID: 200901015514010337
researchmap会員ID: 1000207146

研究キーワード

1

生物学分子腫瘍学

学歴

4

- 1977年

北海道大学
- 1977年

北海道大学
- 1974年

東京学芸大学
- 1974年

東京学芸大学

MISC

28

Genomic structure and promoter activity of the E1AF gene, a member of the ETS oncogene family

S Ishida, F Higashino, M Aoyagi, A Takahashi, T Suzuki, M Shindoh, K Fujinaga, K Yoshida

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 339(1) 325-330 2006年1月
Requirement of STAT3 activation for maximal collagenase-1 (MMP-1) induction by epidermal growth factor and malignant characteristics in T24 bladder cancer cells.

Oncogene 25 1195-204 2006年
E1AF/PEA3 activates the Rho/Rho-associated kinase pathway to increase the malignancy potential of non-small-cell lung cancer cells

N Hakuma, Kinoshita, I, Y Shimizu, K Yamazaki, K Yoshida, M Nishimura, H Dosaka-Akita

CANCER RESEARCH 65(23) 10776-10782 2005年12月
Aberrant Laminin beta3 Isoforms Downstream of EWS-ETS Fusion Genes in Ewing Family Tumors.

Cancer Biol Ther 4 449-55 2005年
ElAF/PEA3 reduces the invasiveness of SiHa cervical cancer cells by activating serine proteinase inhibitor squamous cell carcinoma antigen

M Iwasaki, A Nishikawa, N Akutagawa, T Fujimoto, M Teramoto, Y Sakaguchi, H Kato, M Ito, K Yoshida, R Kudo

EXPERIMENTAL CELL RESEARCH 299(2) 525-532 2004年10月
Induction of Tenascin-C by tumor-specific EWS-ETS fusion genes

G Watanabe, H Nishimori, H Irifune, Y Sasaki, S Ishida, H Zembutsu, T Tanaka, S Kawaguchi, T Wada, J Hata …

GENES CHROMOSOMES & CANCER 36(3) 224-232 2003年3月
A tetraspanin-family protein, T-cell acute lymphoblastic leukemia-associated antigen 1, is induced by the Ewing's sarcoma-Wilms' tumor 1 fusion protein of desmoplastic small round-cell tumor.

Am J Pathol 163 2165-72 2003年
EWS/ETS fusions activate telomerase in Ewing's tumors.

Cancer Res 63 8338-44 2003年
The Id2 gene is a novel target of transcriptional activation by EWS-ETS fusion proteins in Ewing family tumors

H Nishimori, Y Sasaki, K Yoshida, H Irifune, H Zembutsu, T Tanaka, T Aoyama, T Hosaka, S Kawaguchi, T Wada …

ONCOGENE 21(54) 8302-8309 2002年11月
Anti-invasive effect of MMI-166, a new selective matrix metalloproteinase inhibitor, in cervical carcinoma cell lines

M Iwasaki, A Nishikawa, T Fujimoto, N Akutagawa, K Manase, T Endo, K Yoshida, R Maekawa, T Yoshioka, R Kudo

GYNECOLOGIC ONCOLOGY 85(1) 103-107 2002年4月
Lack of matrix metalloproteinase (MMP)-1 and -3 expression in Ewing sarcoma may be due to loss of accessibility of the MMP regulatory element to the specific fusion protein in vivo.

Biochem Biophys Res Commun 293(1) 61-71 2002年
Expression of E1AF/PEA3, an Ets-related transcription factor in human non-small-cell lung cancers: its relevance in cell motility and invasion.

Int J Cancer 93(6) 786-791 2001年
Hepatocyte growth factor upregulates E1AF that induces oral squamous cell carcinoma cell invasion by activating matrix metalloproteinase genes

M Hanzawa, M Shindoh, F Higashino, M Yasuda, N Inoue, K Hida, M Ono, T Kohgo, M Nakamura, K Notani …

CARCINOGENESIS 21(6) 1079-1085 2000年6月
Increased E1AF expression in mouse fibrosarcoma promotes metastasis through induction of MT1-MMP expression

H Habelhah, F Okada, M Kobayashi, K Nakai, SK Choi, J Hamada, T Moriuchi, M Kaya, K Yoshida, K Fujinaga …

ONCOGENE 18(9) 1771-1776 1999年3月
ETS遺伝子ファミリーと癌

医学のあゆみ 190 701-707 1999年
ETS gene family and cancer

Igaku no ayumi 190 701-707 1999年
Molecular analysis of Ewing's sarcoma: another fusion gene, EWS-E1AF, available for diagnosis.

Jpn J Cancer Res 89 703-11 1998年
The genomic breakpoint and chimeric transcripts in the EWSR1-ETV4/E1AF gene fusion in Ewing sarcoma.

Cytogenet Cell Genet 82 278-83 1998年
The Ets-1 and Ets-2 transcription factors activate the promoters for invasion-associated urokinase and collagenase genes in response to epidermal growth factor.

Int J Cancer 77(1) 128-137 1998年
Two transcription factors, E1AF and N-myc, correlate with the invasiveness of neuroblastoma cell lines

K Taguchi, K Yoshida, F Sasaki, K Fujinaga

JAPANESE JOURNAL OF CANCER RESEARCH 88(4) 394-400 1997年4月

もっとみる

所属学協会

4

共同研究・競争的資金等の研究課題

2