Michiyuki Yamada

Profile Information

Affiliation: Graduate School of Medical Life Science, Yokohama City University

Degree: (BLANK)

J-GLOBAL ID: 200901094705860451
researchmap Member ID: 1000207374

External link: http://yamada.sci.yokohama-cu.ac.jp

Research Interests

Research Areas

Research History

1981 - 1993

大阪大学たんぱく質研究所助教授
1981 - 1993

Osaka University, Institute for Protein
1968 - 1981

国立がんセンター研究所研究員・室長
1968 - 1981

National Cancer Research Institute
1975 - 1977

ロッシュ分子生物学研究所研究員(米国)
1975 - 1977

Roche Institute of Molecular Biology(U.S.A)
Research
Yokohama City University International Graduate School of Arts and Sciences

Education

- 1968

Osaka University
- 1968

Graduate School, Division of Natural Science, Osaka University

Papers

Neutrophil extracellular trap components in fibrinoid necrosis of the kidney with myeloperoxidase-ANCA-associated vasculitis

Masaharu Yoshida, Mariko Sasaki, Kentaro Sugisaki, Yutaka Yamaguchi, Michiyuki Yamada

Clinical Kidney Journal, 6(3) 308-312, Jun, 2013 Peer-reviewed
Dynamic expression of peptidylarginine deiminase 2 in human monocytic leukaemia THP-1 cells during macrophage differentiation

Ikuko Hojo-Nakashima, Ryo Sato, Katsuhiko Nakashima, Teruki Hagiwara, Michiyuki Yamada

Journal of Biochemistry, 146(4) 471-479, Oct, 2009 Peer-reviewed
1P024 Structural basis for histone recognition and inhibition mechanism of human peptidylarginine deiminase 4(1. Protein structure and dynamics (I),Poster Session,Abstract,Meeting Program of EABS & BSJ 2006)

Arita Kyouhei, Luo Yuan, Thompson Paul, Shimizu Toshiyuki, Hashimoto Hiroshi, Hidaka Yuji, Yamada Michiyuki, Sato Mamoru

Seibutsu Butsuri, 46(2) S152, 2006
Methylation of the guanidino group of arginine residues prevents citrullination by peptidylarginine deiminase IV

Yuji Hidaka, Teruki Hagiwara, Michiyuki Yamada

FEBS Letters, 579(19) 4088-4092, Aug 1, 2005 Peer-reviewed
Deimination of histone H2A and H4 at arginine 3 in HL-60 granulocytes

T Hagiwara, Y Hidaka, M Yamada

BIOCHEMISTRY, 44(15) 5827-5834, Apr, 2005 Peer-reviewed
Mechanism of the substrate recognition of peptidylarginine Deiminase V

Yuji Hidaka, Teruki Hagiwara, Michiyuki Yamada

Peptides 2004, Proceedings, 637-638, 2005 Peer-reviewed
Histone deimination antagonizes arginine methylation

Graeme L. Cuthbert, Sylvain Daujat, Andrew W. Snowden, Hediye Erdjument-Bromage, Teruki Hagiwara, Michiyuki Yamada, Robert Schneider, Philip D. Gregory, Paul Tempst, Andrew J. Bannister …

Cell, 118(5) 545-553, Sep 3, 2004 Peer-reviewed
Environmental pollutant tributyltin promotes Th2 polarization and exacerbates airway inflammation

T Kato, R Uchikawa, M Yamada, N Arizono, S Oikawa, S Kawanishi, A Nishio, H Nakase, K Kuribayashi

EUROPEAN JOURNAL OF IMMUNOLOGY, 34(5) 1312-1321, May, 2004
Nuclear localization of peptidylarginine deiminase V and histone deimination in granulocytes

Katsuhiko Nakashima, Teruki Hagiwara, Michiyuki Yamada

Journal of Biological Chemistry, 277(51) 49562-49568, Dec 20, 2002 Peer-reviewed
Deimination of arginine residues in nucleophosmin/B23 and histones in HL-60 granulocytes

T Hagiwara, K Nakashima, H Hirano, T Senshu, M Yamada

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 290(3) 979-983, Jan, 2002 Peer-reviewed

Misc.

Structural basis for histone N-terminal recognition by human peptidylarginine deiminase 4.

Kyouhei Arita, Toshiyuki Shimizu, Hiroshi Hashimoto, Yuji Hidaka, Michiyuki Yamada, Mamoru Sato

Proceedings of the National Academy of Sciences of the United States of America, 103(14) 5291-6, Apr 4, 2006
Interactions of heterogeneous nuclear ribonucloprotein D-like protein JKTBP and its domains with high-affinity binding sites

D Kamei, M Yamada

GENE, 298(1) 49-57, Sep, 2002
Interactions of heterogeneous nuclear ribonucloprotein D-like protein JKTBP and its domains with high-affinity binding sites

D Kamei, M Yamada

GENE, 298(1) 49-57, Sep, 2002
Identification of the nucleocytoplasmic shuttling sequence of heterogeneous nuclear ribonucleoprotein D-like protein JKTBP and its interaction with mRNA

H Kawamura, Y Tomozoe, T Akagi, D Kamei, M Ochiai, M Yamada

JOURNAL OF BIOLOGICAL CHEMISTRY, 277(4) 2732-2739, Jan, 2002
Identification of the nucleocytoplasmic shuttling sequence of heterogeneous nuclear ribonucleoprotein D-like protein JKTBP and its interaction with mRNA

H Kawamura, Y Tomozoe, T Akagi, D Kamei, M Ochiai, M Yamada

JOURNAL OF BIOLOGICAL CHEMISTRY, 277(4) 2732-2739, Jan, 2002
Immunocytochemical localization of peptidylarginine deiminase in human eosinophils and neutrophils

H Asaga, K Nakashima, T Senshu, A Ishigami, M Yamada

JOURNAL OF LEUKOCYTE BIOLOGY, 70(1) 46-51, Jul, 2001
A highly sensitive high-performance liquid chromatography-fluorometric method for the assay of peptidylarginine deiminase activity

T Chikuma, M Yamada, A Tsuda, M Yamamoto, K Nakashima, R Yajima, T Kato

ANALYTICAL BIOCHEMISTRY, 285(2) 230-234, Oct, 2000
Molecular characterization of a mouse heterogeneous nuclear ribonucleoprotein D-like protein JKTBP and its tissue-specific expression

T Akagi, D Kamei, N Tsuchiya, Y Nishina, H Horiguchi, M Matsui, H Kamma, M Yamada

GENE, 245(2) 267-273, Mar, 2000
Molecular characterization of peptidylarginine deiminase in HL-60 cells induced by retinoic acid and 1 alpha,25-dihydroxyvitamin D-3

K Nakashima, T Hagiwara, A Ishigami, S Nagata, H Asaga, M Kuramoto, T Senshu, M Yamada

JOURNAL OF BIOLOGICAL CHEMISTRY, 274(39) 27786-27792, Sep, 1999
Two forms of expression and genomic structure of the human heterogeneous nuclear ribonucleoprotein D-like JKTBP gene (HNRPDL)

D Kamei, N Tsuchiya, M Yamazaki, H Meguro, M Yamada

GENE, 228(1-2) 13-22, Mar, 1999
Generation of hydrogen peroxide precedes loss of mitochondrial membrane potential during DNA alkylation-induced apoptosis

S Tada-Oikawa, S Oikawa, M Kawanishi, M Yamada, S Kawanishi

FEBS LETTERS, 442(1) 65-69, Jan, 1999
Molecular cloning of two novel types of peptidylarginine deiminase cDNAs from retinoic acid-treated culture of a newborn rat keratinocyte cell line

A Ishigami, M Kuramoto, M Yamada, K Watanabe, T Senshu

FEBS LETTERS, 433(1-2) 113-118, Aug, 1998
Cloning and characterization of three isoforms of OS-9 cDNA and expression of the OS-9 gene in various human tumor cell lines

Y Kimura, M Nakazawa, M Yamada

JOURNAL OF BIOCHEMISTRY, 123(5) 876-882, May, 1998
Cloning and characterization of a cDNA encoding a novel heterogeneous nuclear ribonucleoprotein-like protein and its expression in myeloid leukemia cells

N Tsuchiya, D Kamei, A Takano, T Matsui, M Yamada

JOURNAL OF BIOCHEMISTRY, 123(3) 499-507, Mar, 1998
Selective deimination of vimentin in calcium ionophore-induced apoptosis of mouse peritoneal macrophages

H Asaga, M Yamada, T Senshu

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 243(3) 641-646, Feb, 1998
Binding of glucocerebrosidase of a microsomal membrene and requirment of a tertairy struture for binding.

Res. Commun. Biochem. Molec. Biol., 2 223-233, 1998
Endocytosis of myeloperoxidase by human monocyte-derived macrophages and multistep regulation of mannose receptor activity during macrophage differentiation

T Ono, K Imai, M Yamada, N Nagasue

JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION, 25(3) 109-119, 1998
Genomic organization of the OS-9 gene amplified in human sarcomas

Y Kimura, M Nakazawa, N Tsuchiya, S Asakawa, N Shimizu, M Yamada

JOURNAL OF BIOCHEMISTRY, 122(6) 1190-1195, Dec, 1997
IDENTIFICATION OF TRANSCRIPTIONAL CIS-ELEMENTS IN INTRON-7 AND INTRON-9 OF THE MYELOPEROXIDASE GENE

M YAMADA, M YOSHIDA, K HASHINAKA

JOURNAL OF BIOLOGICAL CHEMISTRY, 268(18) 13479-13485, Jun, 1993
骨髄性白血病HL-60細胞の細胞分化と遺伝子発現の調節

山田道之, 橋中一也

蛋白質核酸酵素, 36(1) 41-53, 1991

Professional Memberships

Research Projects

Modification of histones by peptidylarginine deiminase and its biological significance

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, 2003 - 2004

YAMADA Michiyuki
Cloning of novel anti-oxidative-stress genes form hydrogen peroxide-and nitric oxide-resistant cells

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, 2000 - 2001

NISHIKIMI Morirnitsu, YAMADA Michio, INAI Yoko
顆粒球分化における転写因子の役割

科学研究費助成事業, 重点領域研究, 日本学術振興会, 1995 - 1995

山田道之
マンノース6-燐酸非依存性のリソソーム酵素の識別機構

科学研究費助成事業, 重点領域研究, 日本学術振興会, 1994 - 1994

今井勝行, 辻省次, 山田道之
Gene Expression of Myeloperoxidase during Granulocyte Differentiation

Grants-in-Aid for Scientific Research, Grant-in-Aid for General Scientific Research (C), Japan Society for the Promotion of Science, 1993 - 1994

YAMADA Michiyuki, YAMADA Michiyuki
マンノース6-リン酸非依存性のリソソーム酵素の識別機構

科学研究費助成事業, 重点領域研究, 日本学術振興会, 1993 - 1993

今井勝行, 辻省次, 山田道之
マンノース6-リン酸非依存性のリソソーム酵素の識別機構

科学研究費助成事業, 重点領域研究, 日本学術振興会, 1992 - 1992

今井勝行, 辻省次, 山田道之
顆粒球の発生の初期に特異的なミエロペルオキシダーゼの発現機構

科学研究費助成事業, 重点領域研究, 日本学術振興会, 1991 - 1991

山田道之
顆粒球の発生の初期に特異的なミエロペルオキシダ-ゼの発現機構

科学研究費助成事業, 重点領域研究, 日本学術振興会, 1991 - 1991

山田道之
Regulation of Myeloperoxidase Gene Expression in Polymorphonuclear Leukocytes

Grants-in-Aid for Scientific Research, Grant-in-Aid for General Scientific Research (C), Japan Society for the Promotion of Science, 1989 - 1990

YAMADA Michiyuki
Role of the Processing at Amino-Terminus on the Regulation of Half-life of Protein

Grants-in-Aid for Scientific Research, Grant-in-Aid for international Scientific Research, Japan Society for the Promotion of Science, 1988 - 1990

TSUNASAWA Susumu, BULGAC Ellena, STERNGLANZ Rolf, MOERSCHELL Richard, DUMONT Mark, SHERMAN Fred, KATO Ikunoshin, YAMADA Michiyuki
造血幹細胞の不死化・白血病化によるクローン性増殖発展の制御機構

科学研究費助成事業, がん特別研究, 日本学術振興会, 1989 - 1989

三浦恭定, 北村幸彦, 山田道之, 高久史磨, 井上達, 井川洋二
造血幹細胞の不死化・白血病化によるクローン性増殖発展の制御機構

科学研究費助成事業, がん特別研究, 日本学術振興会, 1988 - 1988

三浦恭定, 北村幸彦, 山田道之, 高久史麿, 井上達, 井川洋二
血液幹細胞のクローン性増殖から白血病への進展

科学研究費助成事業, がん特別研究, 日本学術振興会, 1987 - 1987

北村幸彦, 森和博, 山田道之, 須田年生, 田ノ岡宏, 高久史麿
Bilogical Roles on N-Acylamino Acid Releasing-enzyme-especially on the protein myristylation-

Grants-in-Aid for Scientific Research, Grant-in-Aid for General Scientific Research (C), Japan Society for the Promotion of Science, 1986 - 1987

TSUNASAWA Susumu, YAMADA Michiyuki
HL-60細胞におけるミエロペルオキシダーゼmRNAの生合成と制御機構

科学研究費助成事業, 一般研究(C), 日本学術振興会, 1986 - 1986

山田道之
血液幹細胞のクローン性増殖から白血病への進展

科学研究費助成事業, がん特別研究, 日本学術振興会, 1986 - 1986

北村幸彦, 森和博, 山田道之, 須田年生, 田ノ岡宏, 高久史麿
ヒトミエロペルオキシダーゼのモノクローナル抗体の作製と白血病の診断への利用

科学研究費助成事業, がん特別研究, 日本学術振興会, 1985 - 1985

山田道之
白血病細胞の増殖分化に伴う遺伝子発現調節の分子機構
Molecular mechanism of Gene Expression in Growth and Differentiation of Leukemia Cells

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