ITOH Kunihiko

J-GLOBAL         Last updated: Nov 7, 2018 at 10:41
 
Avatar
Name
ITOH Kunihiko
Affiliation
University of Shizuoka
Section
School of Pharmaceutical Sciences
Job title
Professor
Degree
Ph.D(Tohoku University)

Research Areas

 
 

Academic & Professional Experience

 
1993
 - 
1995
Res Asooc, The Scripps Res Inst
 
1990
 - 
1992
The fellowship of young scientists from JSPS.
 
1992
 - 
1995
Research Associate, School of Medicine, Tohoku University.
 
1993
 - 
1995
Research Associate, Department of Molecular Biology, The Scripps Research Institute.
 
1995
 - 
2005
Associate Professor, School of Medicine, Akita University.
 

Education

 
 
 - 
1989
Graduate School, Division of Pharmaceutical Sciences, Tohoku University
 
 
 - 
1984
Faculty of Pharmaceutical Science, Tohoku University
 

Awards & Honors

 
1991
Award of Promotion of Young Scientists from the Tohoku Branch of The Pharmaceutical Society of Japan
 

Published Papers

 
Ishii H, Hirai K, Sugiyama K, Nakatani E, Kimura M, Itoh K
Therapeutic drug monitoring      Aug 2018   [Refereed]
Tsuji D, Suzuki K, Kawasaki Y, Goto K, Matsui R, Seki N, Hashimoto H, Hama T, Yamanaka T, Yamamoto N, Itoh K
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer      Aug 2018   [Refereed]
Hirai K, Shirai T, Suzuki M, Shimomura T, Itoh K
The Journal of allergy and clinical immunology   142(2) 663-665.e3   Aug 2018   [Refereed]
Shirai T, Hirai K, Gon Y, Maruoka S, Mizumura K, Hikichi M, Holweg C, Itoh K, Inoue H, Hashimoto S
The journal of allergy and clinical immunology. In practice      Jul 2018   [Refereed]
Yokoi M, Tsuji D, Suzuki K, Kawasaki Y, Nakao M, Ayuhara H, Kogure Y, Shibata K, Hayashi T, Hirai K, Inoue K, Hama T, Takeda K, Nishio M, Itoh K
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer   26(5) 1505-1513   May 2018   [Refereed]
Egami Y, Narushima Y, Ohshima M, Yoshida A, Yoneta N, Masaki Y, Itoh K
Journal of biochemistry   163(1) 61-68   Jan 2018   [Refereed]
Otake A, Tsuji D, Taku K, Kawasaki Y, Yokoi M, Nakamori H, Osada M, Matsumoto M, Inoue K, Hirai K, Itoh K
European journal of clinical pharmacology   73(8) 1033-1039   Aug 2017   [Refereed]
Hirai K, Ishii H, Shimoshikiryo T, Shimomura T, Tsuji D, Inoue K, Kadoiri T, Itoh K
Therapeutic drug monitoring   38(6) 706-710   Dec 2016   [Refereed]
Tsuji D, Ikeda M, Yamamoto K, Nakamori H, Kim YI, Kawasaki Y, Otake A, Yokoi M, Inoue K, Hirai K, Nakamichi H, Tokou U, Shiokawa M, Itoh K
Medicine   95(44) e5151   Nov 2016   [Refereed]
Hirai K, Shimomura T, Moriwaki H, Ishii H, Shimoshikiryo T, Tsuji D, Inoue K, Kadoiri T, Itoh K
European journal of clinical pharmacology   72(10) 1177-1183   Oct 2016   [Refereed]
Inoue K, Murofushi T, Nagaoka K, Ando N, Hakamata Y, Suzuki A, Umemura A, Yoshida Y, Hirai K, Tsuji D, Itoh K
Biological & pharmaceutical bulletin   39(9) 1508-1513   Sep 2016   [Refereed]
Hirai K, Ihara S, Kinae A, Ikegaya K, Suzuki M, Hirano K, Itoh K
Therapeutic drug monitoring   38(3) 393-397   Jun 2016   [Refereed]
Inoue K, Yamamoto Y, Suzuki E, Takahashi T, Umemura A, Takahashi Y, Imai K, Inoue Y, Hirai K, Tsuji D, Itoh K
European journal of clinical pharmacology   72(5) 555-562   May 2016   [Refereed]
Todoroki K, Nakano T, Eda Y, Ohyama K, Hayashi H, Tsuji D, Min JZ, Inoue K, Iwamoto N, Kawakami A, Ueki Y, Itoh K, Toyo'oka T
Analytica chimica acta   916 112-119   Apr 2016   [Refereed]
Inoue K, Takahashi T, Yamamoto Y, Suzuki E, Takahashi Y, Imai K, Inoue Y, Hirai K, Tsuji D, Itoh K
Seizure   33 76-80   Dec 2015   [Refereed]
Tazoe Y, Hayashi H, Tsuboi S, Shioura T, Matsuyama T, Yamada H, Hirai K, Tsuji D, Inoue K, Sugiyama T, Itoh K
Drug metabolism and pharmacokinetics   30(3) 227-230   Jun 2015   [Refereed]
Hirai K, Yamada Y, Hayashi H, Tanaka M, Izumiya K, Suzuki M, Yoshizawa M, Moriwaki H, Akimoto T, Tsuji D, Inoue K, Itoh K
Thrombosis research   135(5) 861-866   May 2015   [Refereed]
Ikeda M, Tsuji D, Yamamoto K, Kim YI, Daimon T, Iwabe Y, Hatori M, Makuta R, Hayashi H, Inoue K, Nakamichi H, Shiokawa M, Itoh K
Drug metabolism and pharmacokinetics   30(2) 149-153   Apr 2015   [Refereed]
Mishima E, Jinno D, Akiyama Y, Itoh K, Nankumo S, Shima H, Kikuchi K, Takeuchi Y, Elkordy A, Suzuki T, Niizuma K, Ito S, Tomioka Y, Abe T
PloS one   10(11) e0143756   2015   [Refereed]
Mishima E, Inoue C, Saigusa D, Inoue R, Ito K, Suzuki Y, Jinno D, Tsukui Y, Akamatsu Y, Araki M, Araki K, Shimizu R, Shinke H, Suzuki T, Takeuchi Y, Shima H, Akiyama Y, Toyohara T, Suzuki C, Saiki Y, Tominaga T, Miyagi S, Kawagisihi N, Soga T, Ohkubo T, Yamamura K, Imai Y, Masuda S, Sabbisetti V, Ichimura T, Mount DB, Bonventre JV, Ito S, Tomioka Y, Itoh K, Abe T
Journal of the American Society of Nephrology : JASN   25(10) 2316-2326   Oct 2014   [Refereed]
[111th Scientific Meeting of the Japanese Society of Internal Medicine: Symposium: 2. Perspective of treatment in the vascular lesion of various organs; 5) Biological aspect of chronic kidney disease and the new therapy].
Abe T, Mishima E, Itoh K, Hayashi K
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine   103(9) 2158-2162   Sep 2014   [Refereed]
Inoue K, Suzuki E, Takahashi T, Yamamoto Y, Yazawa R, Takahashi Y, Imai K, Miyakawa K, Inoue Y, Tsuji D, Hayashi H, Itoh K
Epilepsy research   108(6) 1046-1051   Aug 2014   [Refereed]
Inoue K, Suzuki E, Yazawa R, Yamamoto Y, Takahashi T, Takahashi Y, Imai K, Koyama S, Inoue Y, Tsuji D, Hayashi H, Itoh K
Therapeutic drug monitoring   36(3) 406-409   Jun 2014   [Refereed]
Saito M, Kondo M, Ohshima M, Deguchi K, Hayashi H, Inoue K, Tsuji D, Masuko T, Itoh K
Cancer science   105(4) 396-401   Apr 2014   [Refereed]
Yokoyama Y, Tomatsuri M, Hayashi H, Hirai K, Ono Y, Yamada Y, Todoroki K, Toyo'oka T, Yamada H, Itoh K
Journal of pharmaceutical and biomedical analysis   89 227-232   Feb 2014   [Refereed]
Yokoyama Y, Osano A, Hayashi H, Itoh K, Okura T, Deguchi Y, Ito Y, Yamada S
Biological & pharmaceutical bulletin   37(3) 461-465   2014   [Refereed]
Osano A, Yokoyama Y, Hayashi H, Itoh K, Okura T, Deguchi Y, Ito Y, Yamada S
Journal of pharmacological sciences   124(1) 86-91   2014   [Refereed]
Yamamoto Y, Takahashi Y, Imai K, Mishima N, Yazawa R, Inoue K, Itoh K, Kagawa Y, Inoue Y
Epilepsia   54(6) 983-989   Jun 2013   [Refereed]
Inoue K, Sonobe M, Kawamura Y, Etoh T, Takagi M, Matsumura T, Kikuyama M, Kimura M, Minami S, Utsuki H, Yamazaki T, Suzuki T, Tsuji D, Hayashi H, Itoh K
The Tohoku journal of experimental medicine   229(2) 107-114   Feb 2013   [Refereed]
Fujii S, Hayashi H, Itoh K, Yamada S, Deguchi Y, Kawazu K
The Journal of pharmacy and pharmacology   65(2) 171-180   Feb 2013   [Refereed]
Tsuji D, Kamezato M, Daimon T, Taku K, Hatori M, Ikeda M, Hayashi H, Inoue K, Eto T, Itoh K
Chemotherapy   59(6) 407-413   2013   [Refereed]
Tsuji D, Kim YI, Nakamichi H, Daimon T, Suwa K, Iwabe Y, Hayashi H, Inoue K, Yoshida M, Itoh K
Drug metabolism and pharmacokinetics   28(4) 299-304   2013   [Refereed]
Hayashi H, Tazoe Y, Tsuboi S, Horino M, Morishita M, Arai T, Ohshima M, Matsuyama T, Kosuge K, Yamada H, Tsuji D, Inoue K, Itoh K
Drug metabolism and pharmacokinetics   28(2) 164-168   2013   [Refereed]
Hirai K, Hayashi H, Ono Y, Izumiya K, Tanaka M, Suzuki T, Sakamoto T, Itoh K
Drug metabolism and pharmacokinetics   28(2) 132-137   2013   [Refereed]
Yamamoto Y, Takahashi Y, Suzuki E, Mishima N, Inoue K, Itoh K, Kagawa Y, Inoue Y
Epilepsy research   101(3) 202-209   Sep 2012   [Refereed]
Itoh K
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan   132(1) 31-34   2012   [Refereed]
Hayashi H, Tazoe Y, Horino M, Fujimaki-Katoh C, Tsuboi S, Matsuyama T, Kosuge K, Yamada H, Tsuji D, Inoue K, Itoh K
Drug metabolism and pharmacokinetics   27(2) 263-267   Dec 2011   [Refereed]
Yoshida A, Hirooka Y, Sugata Y, Nitta M, Manabe T, Ido S, Murakami K, Saha RK, Suzuki T, Ohshima M, Yoshida A, Itoh K, Shimizu K, Oku N, Furuta T, Asakawa T, Wakimoto T, Kan T
Chemical communications (Cambridge, England)   47(6) 1794-1796   Feb 2011   [Refereed]
Ohshima M, Inoue K, Hayashi H, Tsuji D, Mizugaki M, Itoh K
Protein engineering, design & selection : PEDS   23(11) 881-888   Nov 2010   [Refereed]
Urushibata Y, Itoh K, Ohshima M, Seto Y
Clinical and vaccine immunology : CVI   17(11) 1708-1717   Nov 2010   [Refereed]
Itoh K, Tsuruya R, Shimoyama T, Watanabe H, Miyazaki S, D'Emanuele A, Attwood D
Drug development and industrial pharmacy   36(4) 449-455   Apr 2010   [Refereed]
Itoh K, Hatakeyama T, Kimura T, Shimoyama T, Miyazaki S, D'Emanuele A, Attwood D
Chemical & pharmaceutical bulletin   58(2) 247-249   Feb 2010   [Refereed]
Ohshima M, Tadakuma T, Hayashi H, Inoue K, Itoh K
Journal of biochemistry   147(1) 135-141   Jan 2010   [Refereed]
Hayashi H, Horino M, Morishita M, Tazoe Y, Tsuboi S, Matsuyama T, Kosuge K, Yamada H, Tsuji D, Inoue K, Itoh K
Drug metabolism and pharmacokinetics   25(5) 516-518   2010   [Refereed]
Yoshizawa M, Hayashi H, Tashiro Y, Sakawa S, Moriwaki H, Akimoto T, Doi O, Kimura M, Kawarasaki Y, Inoue K, Itoh K
Thrombosis research   124(2) 161-166   Jun 2009   [Refereed]
Fujimaki C, Hayashi H, Tsuboi S, Matsuyama T, Kosuge K, Yamada H, Inoue K, Itoh K
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals   14(1) 49-54   Feb 2009   [Refereed]
Itoh K, Ohshima M, Sonobe M, Saito M, Yoshida A, Hayashi H, Inoue K, Masuko T
Cancer science   100(1) 126-131   Jan 2009   [Refereed]
Hayashi H, Fujimaki C, Tsuboi S, Matsuyama T, Daimon T, Itoh K
The Tohoku journal of experimental medicine   215(1) 95-101   May 2008   [Refereed]
Yoshida K, Higuchi H, Takahashi H, Kamata M, Sato K, Inoue K, Suzuki T, Itoh K, Ozaki N
Human psychopharmacology   23 121-128   Mar 2008   [Refereed]
Itoh K, Inoue K, Hayashi H, Suzuki T, Masuko T
Cancer science   98(11) 1696-1700   Nov 2007   [Refereed]
Inoue K, Itoh K, Yoshida K, Higuchi H, Kamata M, Takahashi H, Shimizu T, Suzuki T
Biological & pharmaceutical bulletin   30(10) 1996-1998   Oct 2007   [Refereed]
Yoshida K, Higuchi H, Kamata M, Takahashi H, Inoue K, Suzuki T, Itoh K, Ozaki N
Journal of psychopharmacology (Oxford, England)   21 650-656   Aug 2007   [Refereed]
Hayashi H, Fujimaki C, Inoue K, Suzuki T, Itoh K
Biological & pharmaceutical bulletin   30(4) 839-841   Apr 2007   [Refereed]
Dong L, Masaki Y, Takegami T, Kawanami T, Itoh K, Jin ZX, Huang CR, Tong XP, Fukushima T, Tanaka M, Sawaki T, Sakai T, Sugai S, Okazaki T, Hirose Y, Umehara H
International immunology   19(3) 331-336   Mar 2007   [Refereed]
Itoh K
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan   127(1) 43-53   Jan 2007   [Refereed]
Masaki Y, Itoh K, Sawaki T, Karasawa H, Kawanami T, Fukushima T, Kawabata H, Wano Y, Hirose Y, Suzuki T, Sugai S, Umehara H
Clinica chimica acta; international journal of clinical chemistry   371 148-151   Sep 2006   [Refereed]
Seki Y, Hayashi K, Itoh K, Mizugaki M, Saitou M, Matsui Y
Developmental biology   278(2) 440-458   Feb 2005   [Refereed]
Yoshida K, Takahashi H, Higuchi H, Kamata M, Ito K, Sato K, Naito S, Shimizu T, Itoh K, Inoue K, Suzuki T, Nemeroff CB
The American journal of psychiatry   161 1575-1580   Sep 2004   [Refereed]
Inoue K, Itoh K, Nakao H, Takeda T, Suzuki T
The Tohoku journal of experimental medicine   203(4) 295-303   Aug 2004   [Refereed]
Inoue K, Itoh K, Yoshida K, Shimizu T, Suzuki T
Neuropsychobiology   50 301-304   2004   [Refereed]
Tsuruta LR, Tomioka Y, Hishinuma T, Kato Y, Itoh K, Suzuki T, Oguri H, Hirama M, Goto J, Mizugaki M
Prostaglandins, leukotrienes, and essential fatty acids   68(4) 273-284   Apr 2003   [Refereed]
Itoh K, Inoue K, Tezuka T, Tada H, Hashimoto Y, Masuko T, Suzuki T
Journal of biochemistry   133(2) 239-245   Feb 2003   [Refereed]
Yoshida K, Naito S, Takahashi H, Sato K, Ito K, Kamata M, Higuchi H, Shimizu T, Itoh K, Inoue K, Suzuki T, Ohkubo T
Neuropsychobiology   48(1) 10-13   2003   [Refereed]
Yoshida K, Naito S, Takahashi H, Sato K, Ito K, Kamata M, Higuchi H, Shimizu T, Itoh K, Inoue K, Tezuka T, Suzuki T, Ohkubo T, Sugawara K, Otani K
Progress in neuro-psychopharmacology & biological psychiatry   26(7-8) 1279-1283   Dec 2002   [Refereed]
Design, production, and characterization of recombinant neocarzinostatin apoprotein in Escherichia coli.
Nozaki S, Tomioka Y, Hishinuma T, Inoue M, Nagumo Y, Tsuruta LR, Hayashi K, Matsumoto T, Kato Y, Ishiwata S, Itoh K, Suzuki T, Hirama M, Mizugaki M
Journal of biochemistry   131(5) 729-738   May 2002   [Refereed]
Yoshida K, Ito K, Sato K, Takahashi H, Kamata M, Higuchi H, Shimizu T, Itoh K, Inoue K, Tezuka T, Suzuki T, Ohkubo T, Sugawara K, Otani K
Progress in neuro-psychopharmacology & biological psychiatry   26(2) 383-386   Feb 2002   [Refereed]
Tada H, Nakashima A, Awaya A, Fujisaki A, Inoue K, Kawamura K, Itoh K, Masuda H, Suzuki T
Life sciences   70(10) 1213-1223   Jan 2002   [Refereed]
Sato K, Yoshida K, Takahashi H, Ito K, Kamata M, Higuchi H, Shimizu T, Itoh K, Inoue K, Tezuka T, Suzuki T, Ohkubo T, Sugawara K, Otani K
Neuropsychobiology   46(3) 136-140   2002   [Refereed]
Antibody-guided selection using capture-sandwich ELISA.
Itoh K, Suzuki T
Methods in molecular biology (Clifton, N.J.)   178 195-199   2002   [Refereed]

Misc

 
Antibody epitope peptides as a potent inducer of IgG antibodies against CD98 oncoprotein
Itoh., K. et al
Cancer Sci.   in press    2008

Research Grants & Projects

 
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(C))
Project Year: 2008 - 2010    Investigator(s): Kunihiko ITOH
I performed the epitope analysis of human recombinant Fab (AHSA) retrieved from a patient with MALT lymphoma using phage display random peptide library. AHSA-derived epitope peptide vaccines were given to BALB/c mice and then antibody Fab librarie...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(C))
Project Year: 2005 - 2006    Investigator(s): Kunihiko ITOH
Anti-CD98 monoclonal antibody, HBJ127 shows growth inhibition in vitro. Since elevated expression of CD98 is detected in tumor tissues, especially in squamous cell carcinomas, anti-tumor immunity may be inducible in the host by active immunization...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(C))
Project Year: 2002 - 2003    Investigator(s): Kunihiko ITOH
The goal of this research project is to prepare human recombinant Fab (rFab) against tumor-associated antigen, CD98 and its application to diagnosis and therapy of tumor diseases. I constructed human IgG1, kappa combinatorial library (1.3 x 10^7 c...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(C))
Project Year: 2001 - 2002    Investigator(s): Toshio SUZUKI
Novel steroids, hemisuccinyl methyl glycolates were prepared from the corresponding methyl glycolates derived from predonisolone and dexamethasone based on a concept of the antedrug. Their topical anti-inflammatory activity was evaluated through c...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(C))
Project Year: 1996 - 1997    Investigator(s): Kunihiko ITOH
The goal of this research project is the establishing of the conventional procedure for making human monoclonal antibodies applicable for the prophylaxis or therapy using phage display system. We have selected rotaviruses as a target since they ar...
Clinical application of recombinant human antibody
Analysis of genetic polymorphisms affecting the clinical responses and adverse effects of drugs