論文

査読有り
2015年5月22日

A case of cellular fibrous histiocytoma on the right elbow with repeated relapse within a short period

Case Reports in Dermatology
  • Kanako Tsunoda
  • ,
  • Hiroki Oikawa
  • ,
  • Fumihiko Maeda
  • ,
  • Kazuhiro Takahashi
  • ,
  • Toshihide Akasaka

7
1
開始ページ
10
終了ページ
16
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1159/000371790
出版者・発行元
S. Karger AG

Cellular fibrous histiocytoma, a variant of fibrous histiocytoma, is a designation used for lesions showing increased cellularity with a fascicular growth pattern and frequent extension into the subcutis. Here we describe a case of cellular fibrous histiocytoma showing repeated recurrence in a 36-year-old woman who initially presented with a 2-cm cutaneous tumor on her right elbow. Histopathologically, the first resected specimen demonstrated irregularly arranged collagen fibers mixed with scattered proliferating plump to spindle-shaped fibrohistiocytes. However, examination of the resected specimens obtained after recurrence showed that the cellularity had increased, the spindle-shaped cells showing monomorphic proliferation with a fascicular and storiform growth pattern extending into the subcutis, as well as an increase of Ki-67 positivity. Since the lesion showed repeated relapse within a short period, we performed wide-field resection of the tumor with a 3-cm margin. Currently, 48 months after surgery, there has been no local recurrence or metastasis, but continuous strict follow-up will be necessary.

リンク情報
DOI
https://doi.org/10.1159/000371790

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