2015年5月22日
A case of cellular fibrous histiocytoma on the right elbow with repeated relapse within a short period
Case Reports in Dermatology
- ,
- ,
- ,
- ,
- 巻
- 7
- 号
- 1
- 開始ページ
- 10
- 終了ページ
- 16
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1159/000371790
- 出版者・発行元
- S. Karger AG
Cellular fibrous histiocytoma, a variant of fibrous histiocytoma, is a designation used for lesions showing increased cellularity with a fascicular growth pattern and frequent extension into the subcutis. Here we describe a case of cellular fibrous histiocytoma showing repeated recurrence in a 36-year-old woman who initially presented with a 2-cm cutaneous tumor on her right elbow. Histopathologically, the first resected specimen demonstrated irregularly arranged collagen fibers mixed with scattered proliferating plump to spindle-shaped fibrohistiocytes. However, examination of the resected specimens obtained after recurrence showed that the cellularity had increased, the spindle-shaped cells showing monomorphic proliferation with a fascicular and storiform growth pattern extending into the subcutis, as well as an increase of Ki-67 positivity. Since the lesion showed repeated relapse within a short period, we performed wide-field resection of the tumor with a 3-cm margin. Currently, 48 months after surgery, there has been no local recurrence or metastasis, but continuous strict follow-up will be necessary.
- リンク情報
- ID情報
-
- DOI : 10.1159/000371790
- ISSN : 1662-6567
- SCOPUS ID : 84929579263