Tanaka Toshihisa (Toshihisa Tanaka) - マイポータル

基本情報

所属: 大阪大学大学院医学系研究科

学位: 博士(医学)(大阪大学)

J-GLOBAL ID: 200901078691947871
researchmap会員ID: 1000220406

研究キーワード

経歴

2002年 - 2004年

: 大阪大学医学部講師
2002年 - 2004年

: Assistant Professor, Faculty of Medicine,
1997年 - 2002年

: 大阪大学医学部助手
1997年 - 2002年

: Research Associate, Faculty of Medicine,
大阪大学

学歴

委員歴

MISC

Differential interaction and aggregation of 3-repeat and 4-repeat tau isoforms with 14-3-3 zeta protein

Golam Sadik, Toshihisa Tanaka, Kiyoko Kato, Kentaro Yanagi, Takashi Kudo, Masatoshi Takeda

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 383(1) 37-41 2009年5月
Differential interaction and aggregation of 3-repeat and 4-repeat tau isoforms with 14-3-3 zeta protein

Golam Sadik, Toshihisa Tanaka, Kiyoko Kato, Kentaro Yanagi, Takashi Kudo, Masatoshi Takeda

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 383(1) 37-41 2009年5月
Destruxin E Decreases Beta-Amyloid Generation by Reducing Colocalization of Beta-Amyloid-Cleaving Enzyme 1 and Beta-Amyloid Protein Precursor

Naohiro Itoh, Masayasu Okochi, Shinji Tagami, Kouhei Nishitomi, Taisuke Nakayama, Kanta Yanagida, Akio Fukumori, Jingwei Jiang, Kohji Mori, Motoko Hosono …

NEURODEGENERATIVE DISEASES 6(5-6) 230-239 2009年
Phosphorylation of tau at Ser214 mediates its interaction with 14-3-3 protein: implications for the mechanism of tau aggregation

Golam Sadik, Toshihisa Tanaka, Kiyoko Kato, Hidenaga Yamamori, Begum Nurun Nessa, Takashi Morihara, Masatoshi Takeda

JOURNAL OF NEUROCHEMISTRY 108(1) 33-43 2009年1月
Destruxin E Decreases Beta-Amyloid Generation by Reducing Colocalization of Beta-Amyloid-Cleaving Enzyme 1 and Beta-Amyloid Protein Precursor

Naohiro Itoh, Masayasu Okochi, Shinji Tagami, Kouhei Nishitomi, Taisuke Nakayama, Kanta Yanagida, Akio Fukumori, Jingwei Jiang, Kohji Mori, Motoko Hosono …

NEURODEGENERATIVE DISEASES 6(5-6) 230-239 2009年
Phosphorylation of tau at Ser214 mediates its interaction with 14-3-3 protein: implications for the mechanism of tau aggregation

Golam Sadik, Toshihisa Tanaka, Kiyoko Kato, Hidenaga Yamamori, Begum Nurun Nessa, Takashi Morihara, Masatoshi Takeda

JOURNAL OF NEUROCHEMISTRY 108(1) 33-43 2009年1月
Dynamin 2 gene is a novel susceptibility gene for late-onset Alzheimer disease in non-APOE-epsilon 4 carriers

Nuripa Jenishbekovna Aidaralieva, Kouzin Kamino, Ryo Kimura, Mitsuko Yamamoto, Takeshi Morihara, Hiroaki Kazui, Ryota Hashimoto, Toshihisa Tanaka, Takashi Kudo, Tomoyuki Kida …

JOURNAL OF HUMAN GENETICS 53(4) 296-302 2008年4月
Dynamin 2 gene is a novel susceptibility gene for late-onset Alzheimer disease in non-APOE-epsilon 4 carriers

Nuripa Jenishbekovna Aidaralieva, Kouzin Kamino, Ryo Kimura, Mitsuko Yamamoto, Takeshi Morihara, Hiroaki Kazui, Ryota Hashimoto, Toshihisa Tanaka, Takashi Kudo, Tomoyuki Kida …

JOURNAL OF HUMAN GENETICS 53(4) 296-302 2008年4月
Regulation of Notch signaling by dynamic changes in the precision in S3 cleavage of Notch-1.

Mol Cell Biol 28:165-176 2008年
Mild Cognitive Impairment (MCI) and Subjective Cognitive Impairment (SCI).

Psycogeriatrics 8;155-160 2008年
Regulation of Notch signaling by dynamic changes in the precision in S3 cleavage of Notch-1.

Mol Cell Biol 28:165-176 2008年
Mild Cognitive Impairment (MCI) and Subjective Cognitive Impairment (SCI).

Psycogeriatrics 8;155-160 2008年
Biological markers as outcome measures for Alzheimer's disease interventions - real problems and future possibilities

Masatoshi Takeda, Masayasu Okochi, Shinji Tagami, Toshihisa Tanaka, Takashi Kudo

INTERNATIONAL PSYCHOGERIATRICS 19(3) 391-400 2007年6月
Biological markers as outcome measures for Alzheimer's disease interventions - real problems and future possibilities

Masatoshi Takeda, Masayasu Okochi, Shinji Tagami, Toshihisa Tanaka, Takashi Kudo

INTERNATIONAL PSYCHOGERIATRICS 19(3) 391-400 2007年6月
The DYRK1A gene, encoded in chromosome 21 Down syndrome critical region, bridges between beta-amyloid production and tau phosphorylation in Alzheimer disease

Ryo Kimura, Kouzin Kamino, Mitsuko Yamamoto, Aidaralieva Nuripa, Tomoyuki Kida, Hiroaki Kazui, Ryota Hashimoto, Toshihisa Tanaka, Takashi Kudo, Hidehisa Yamagata …

HUMAN MOLECULAR GENETICS 16(1) 15-23 2007年1月
The DYRK1A gene, encoded in chromosome 21 Down syndrome critical region, bridges between beta-amyloid production and tau phosphorylation in Alzheimer disease

Ryo Kimura, Kouzin Kamino, Mitsuko Yamamoto, Aidaralieva Nuripa, Tomoyuki Kida, Hiroaki Kazui, Ryota Hashimoto, Toshihisa Tanaka, Takashi Kudo, Hidehisa Yamagata …

HUMAN MOLECULAR GENETICS 16(1) 15-23 2007年1月
Toll-like receptor 3 mediated hyperphosphorylation of tau in human SH-SY5Y neuroblastoma cells.

Psychiatry Clin Neurosci. 60 Suppl. 1; S27-S33. 2006年
Toll-like receptor 3 mediated hyperphosphorylation of tau in human SH-SY5Y neuroblastoma cells.

Psychiatry Clin Neurosci. 60 Suppl. 1; S27-S33. 2006年
Amyloid β down-regulates XIAP expression in human SH-SY5Y neuroblostoma cells

Neuro Report 15(5) 851-854 2004年4月9日
Amyloid-β down-regulates XIAP expression in human SH-SY5Y neuroblastoma cells.

NeuroReport 15;851-854. 2004年

もっとみる

書籍等出版物

100 Papers Selection ANNUAL REPORT OF OSAKA UNIVERSITY-Academic Achievement-/2007-2008

Osaka University 2009年
100 Papers Selection ANNUAL REPORT OF OSAKA UNIVERSITY-Academic Achievement-/2007-2008

Osaka University 2009年
現代老年精神医療

永井書店 2005年
現代老年精神医療

永井書店 2005年
Activated protein kinases and phosphorylated tau protein in Alzheimer disease

Molecalar neurobiology of Alzheimer disease and related disorders 2004年
Actirated protein kinases and phosphorylated tau protein in Alzheimer disease

Molecalar neurobiology of Alzheimer disease and related disrders 2004年

所属学協会

共同研究・競争的資金等の研究課題

アルツハイマー病脳における細胞骨格蛋白の変化に関する研究

未来開拓学術研究推進事業
Study on Alteration of Cytoskeletal proteins in Alzheiner disease

Research for the Future Program