This study presents the production and purification of the positron emitting radionuclide 63Zn. A natural copper target was irradiated with 13.5MeV protons, and 63Zn was purified by cation exchange chromatography using 0.05N HCl-85% acetone as eluent. The production yield reached 1.41±0.19 GBq/mμh at the end of bombardment and 169±30 MBq/mAμh after purification, with more than 99.9% of radionuclidic purity with copper content around 0.04mg/g. © 2011 John Wiley &amp
Sons, Ltd.