1996年
A histological analysis of T and B cells in periodontal tissue destruction
Oral Med Pathol
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- 巻
- 1
- 号
- 2
- 開始ページ
- 77
- 終了ページ
- 83
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- 出版者・発行元
- 特定非営利活動法人日本臨床口腔病理学会
We immunohistologically examined the cell densities and distribution of T and B cells in periodontitis and analyzed their relationship in terms of periodontal tissue destruction. Specimens were labeled with monoclonal antibodies for T cells (CD3) and B cells (CD20) and developed using the double staining technique. CD3^+ cells appeared in low density infiltrates and increased gradually with the number of total infiltrates; in contrast, CD20^+ cells did not appear in small infiltrates but increased rapidly with the number of infiltrates. The number of fibroblastic cells negatively correlated with that of the total infiltrates and CD20^+ cells, but it did not correlate with the number of CD3^+ cells. These findings suggest that the T cells infiltrated into the inflamed sites at the onset and increased gradually with the development of inflammation and that B cells infiltrated later than T cells and their number increased rapidly with inflammation.
- リンク情報
- ID情報
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- ISSN : 1342-0984
- CiNii Articles ID : 110002985135
- CiNii Books ID : AA11097826