2016年
Risk Factors for the Requirement of Antenatal Insulin Treatment in Gestational Diabetes Mellitus
Journal of Diabetes Research
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- 巻
- 2016
- 号
- 開始ページ
- 9648798
- 終了ページ
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1155/2016/9648798
- 出版者・発行元
- HINDAWI PUBLISHING CORP
Poor maternal glycemic control increases maternal and fetal risk for adverse outcomes, and strict management of gestational diabetes mellitus (GDM) is recommended to prevent neonatal and maternal complications. However, risk factors for the requirement of antenatal insulin treatment (AIT) are not well-investigated in the pregnant women with GDM. We enrolled 37 pregnant women with GDM and investigated the risk for AIT by comparing the patients with AIT (AIT group; n = 10) and without insulin therapy (Diet group; n = 27). The 1-h and 2-h plasma glucose levels and the number of abnormal values in 75 g OGTT were significantly higher in AIT group compared with Diet group. By logistic regression analysis, plasma glucose level at 1-h was significant predictor for AIT and the odds ratios were 1.115 (1.004-1.239) using forward selection method and 1.192 (1.006-1.413) using backward elimination method. There were no significant differences in obstetrical outcomes and neonatal complications. 1-h plasma glucose levels in 75 g OGTT are useful parameters in predicting the requirement for AIT in GDM. Both maternal and neonatal complications are comparable in GDM patients with and without insulin therapy.
- リンク情報
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- DOI
- https://doi.org/10.1155/2016/9648798
- Web of Science
- https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000389428800001&DestApp=WOS_CPL
- URL
- https://www.ncbi.nlm.nih.gov/pubmed/27995150
- URL
- http://orcid.org/0000-0003-1468-5170
- ID情報
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- DOI : 10.1155/2016/9648798
- ISSN : 2314-6745
- eISSN : 2314-6753
- ORCIDのPut Code : 43365882
- Web of Science ID : WOS:000389428800001