2021年
Lymph Node Stromal Cells: Diverse Meshwork Structures Weave Functionally Subdivided Niches.
Current topics in microbiology and immunology
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- 巻
- 434
- 号
- 開始ページ
- 103
- 終了ページ
- 121
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1007/978-3-030-86016-5_5
Lymph nodes (LNs) are secondary lymphoid organs that function as the first line of defense against invasive foreign substances. Within the LNs, different types of immune cells are strategically localized to induce immune responses efficiently. Such a sophisticated tissue structure is a complex of functionally specialized niches, constructed by a variety of fibroblastic stromal cells. Elucidating the characteristics and functions of the niches and stromal cells will facilitate comprehension of the immune response induced in the LNs. Three recent studies offered novel insights into specialized stromal cells. In our discussion of these surprisingly diverse stromal cells, we will integrate information from these studies to improve knowledge about the structure and niches of LN.
- リンク情報
- ID情報
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- DOI : 10.1007/978-3-030-86016-5_5
- PubMed ID : 34850284