In this talk, firstly we will introduce our developing 14T MRM(Magnetic Resonance Microscopy) system, of which minimum voxel size is about 20μ. And then, we will introduce our project of in vivo imaging of medaka fish for human disease model. It is expected that the development of disease will be able to be visualized at an individual level.Figure on the right column shows PDFF(Proton Density Fat Fraction) map of a medaka fish obtained by using 3d MRM in vivo imaging.