家子正裕 (Masahiro Ieko) - マイポータル - researchmap

基本情報

所属: 北海道医療大学歯学部内科学分野教授
: 北海道大学医学部非常勤講師

学位: 医学博士(北海道大学)

J-GLOBAL ID: 200901082165076111
researchmap会員ID: 1000229540

研究キーワード

7

研究分野

2

経歴

1

1999年 - 現在

北海道医療大学歯学部, 教授

委員歴

5

MISC

61

Soluble fibrin monomer degradation products as a potentially useful marker for hypercoagulable states with accelerated fibrinolysis

Masahiro Ieko, Toru Nakabayashi, Takashi Tarumi, Surniyoshi Naito, Mika Yoshida, Kaori Kanazawa, Kazuhiro Mizukami, Takao Koike

CLINICA CHIMICA ACTA 386(1-2) 38-45 2007年11月
Dabigatran etexilate, a thrombin inhibitor for the prevention of venous thromboembolism and stroke

Ieko M

Curr Opin Investig Drugs 8(9) 758 2007年
Trousseau's syndrome associated with tissue factor produced by pulmonary adenocarcinoma

T. Sato, I. Tsujino, D. Ikeda, M. Ieko, M. Nishimura

THORAX 61(11) 1009-1010 2006年11月
One novel and one recurrent mutation in the PROS1 gene cause type I protein S deficiency in patients with pulmonary embolism associated with deep vein thrombosis

Kazuhiro Mizukami, Toru Nakabayashi, Sumiyoshi Naitoh, Mika Takeda, Takashi Tarumi, Itaru Mizoguchi, Masahiro Ieko, Takao Koike

AMERICAN JOURNAL OF HEMATOLOGY 81(10) 787-797 2006年10月
Susceptibility of brain microvascular endothelial cells to advanced glycation end products-induced tissue factor upregulation is associated with intracellular reactive oxygen species

Yoshimasa Niiya, Takeo Abumiya, Hideo Shichinohe, Satoshi Kuroda, Seiji Kikuchi, Masahiro Ieko, Sho-ichi Yamagishi, Masayoshi Takeuchi, Takashi Sato, Yoshinobu Iwasaki

BRAIN RESEARCH 1108(1) 179-187 2006年9月
Factor Xa inhibitors: new anti-thrombotic agents and their characteristics

Ieko M, Tarumi T, Nakabayashi T, Yoshida M, Naito S, Koike T

Front Biosci 11 232 2006年
Molecular dynamics calculations of wild type vs. mutant protein C: relationship between binding affinity to endothelial cell protein C receptor and hereditary disease

Nakagawa T, Shikamoto Y, Mizuno H, Murase T, Ishii H, Nakabayashi T, Ieko M, Mizukami K, Naitoh S, Takeda M …

J Biomol Struct Dyn 24 203 2006年
Protein C Sapporo (protein C Glu 25 -> Lys): A heterozygous missense mutation in the Gla domain provides new insight into the interaction between protein C and endothelial protein C receptor

T Nakabayashi, K Mizukami, S Naitoh, M Takeda, Y Shikamoto, T Nakagawa, H Kaneko, T Tarumi, Mizoguchi, I, H Mizuno …

THROMBOSIS AND HAEMOSTASIS 94(5) 942-950 2005年11月
Nicked β2-glycoprotein I: a marker of cerebral infarct and a novel role in the negative feedback pathway of extrinsic fibrinolysis.

Yasuda S, Atsumi T, Ieko M, Matsuura E, Kobayashi K, Inagaki J, Kato H, Tanaka H, Yamakado M, Akino M …

Blood 103(10) 3766-3772 2004年5月
: β2-glycoprotein I, anti-β2-glycoprotein I, and fibrinolysis

Yasuda S, Atsumi T, Ieko M, Koike T

Thromb Res 114 465 2004年
Synthetic selective inhibitors of coagulation factor Xa strongly inhibit thrombin generation without affecting initial thrombin forming time necessary for platelet activation in hemostasis

Ieko M, Tarumi T, Takeda M, Naito S, Nakabayashi T, Koike T

J Thromb Haemost 2 612 2004年
Suppressed intrinsic fibrinolytic activity by monoclonal anti-beta-2 glycoprotein I autoantibodies: possible mechanism for thrombosis in patients with antiphospholipid syndrome

R Takeuchi, T Atsumi, M Ieko, Y Amasaki, K Ichikawa, T Koike

BRITISH JOURNAL OF HAEMATOLOGY 119(3) 781-788 2002年12月
The inhibition of protein C anticoagulant activity by anti-β2-glycoprotein I (β2GPI) antibodies isolated from patients with antiphospholipid syndrome by chromatography methods

M. Ieko, T. Nakabayashi, M. Takeda, S. Naitoh, T. Atsumi, T. Koike

Modern Rheumatology 12(1) 44-49 2002年
Multiple thromboses in major arteries in a patient with antiphospholipid syndrome associated with excess of a large multimer of von Willebrand factor

M Mukai, M Ieko, T Atsumi, A Notoya, M Kohno

LUPUS 10(12) 895-896 2001年
Association of autoantibodies against the phosphatidylserine-prothrombin complex with manifestations of the antiphospholipid syndrome and with the presence of lupus anticoagulant

T Atsumi, M Ieko, ML Bertolaccini, K Ichikawa, A Tsutsumi, E Matsuura, T Koike

ARTHRITIS AND RHEUMATISM 43(9) 1982-1993 2000年9月
Effects of beta 2-glycoprotein I and monoclonal anticardiolipin antibodies on extrinsic fibrinolysis

M Ieko, K Ichikawa, T Atsumi, R Takeuchi, KI Sawada, T Yasukouchi, T Koike

SEMINARS IN THROMBOSIS AND HEMOSTASIS 26(1) 85-90 2000年
Coagulation and fibrinolytic activities in 2 siblings with beta(2)-glycoprotein I deficiency

Takeuchi R, Atsumi T, Ieko M, Takeya H, Yasuda S, Ichikawa K, Tsutsumi A, Suzuki K, Koike T

Blood 96(4) 1594 2000年
Association of autoantibodies against the phosphatidylserine-prothrombin complex with manifestations of the antiphospholipid syndrome and with the presence of lupus anticoagulant

Atsumi T, Ieko M, Bertolaccini ML, Ichikawa K, Tsutsumi A, Matsuura E, Koike T

Arthritis Rheum 43(9) 1982 2000年
Coagulation and fibrinolytic activities in 2 siblings with β2-glycoprotein (]G0001[) deficiency.

Blood 96(4) 1594-1595 2000年
Effects of β2-glycoprotein (]G0001[) and monoclonal anticardiolipin antibodies on extrinsic fibrinolysis.

Semin Thromb Hemost 26(1) 85-90 2000年

もっとみる

所属学協会

9

Works(作品等)

4

Xa因子阻害剤のin vitro assayでの凝血学的効果に関する検討

2000年 - 2003年
Evaluation on effects of factor Xa inhibitor in ┣DBin vitro(/)-┫DB coagulation assay

2000年 - 2003年
抗リン脂質抗体症候群における血栓形成機序の検討

2000年
Evaluation on thrombotic mechanism in antiphospholipid syndrome

2000年

共同研究・競争的資金等の研究課題

11