伊藤邦彦 (Kunihiko Itoh) - マイポータル - researchmap

基本情報

所属: 北海道医療大学薬学部准教授

学位: 博士（薬学）(北海道医療大学)

J-GLOBAL ID: 200901070540072449
researchmap会員ID: 1000229552

研究キーワード

4

研究分野

3

経歴

1

2014年 - 現在

北海道医療大学薬学部准教授

委員歴

2

2007年 - 2008年

日本薬学会北海道支部庶務幹事
2006年 - 2007年

日本薬学会北海道支部幹事

受賞

1

2003年

日本薬学会北海道支部奨励賞

MISC

23

Photoregulation of deacylation rate of acyl trypsin derived from photoresponsive inverse substrate

H Sekizaki, A Kumagai, K Itoh, E Toyota, K Horita, Y Noguchi, K Tanizawa

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 13(21) 3809-3812 2003年11月
A facile synthesis of benzofuran derivatives: A useful synthon for preparation of trypsin inhibitor

H Sekizaki, K Itoh, E Toyota, K Tanizawa

HETEROCYCLES 59(1) 237-243 2003年1月
Synthesis and evaluation of guanidine-containing Schiff base copper(II), zinc(II), and iron(III) chelates as trypsin inhibitors

Chem. Pharm. Bull. 51(6) 625-629 2003年
Crystal structure and nucleotide sequence of an anionic trypsin from chum salmon (Oncorhynchus keta) in comparison with Atlantic salmon (Salmo salar) and bovine trypsin

E Toyota, KKS Ng, S Kuninaga, H Sekizaki, K Itoh, K Tanizawa, MNG James

JOURNAL OF MOLECULAR BIOLOGY 324(3) 391-397 2002年11月
Trypsin-catalysed synthesis of oligopeptide amides: Comparison of catalytic efficiency among trypsins of different origin (bovine, Streptomyces griseus and chum salmon)

H Sekizaki, K Itoh, E Toyota, K Tanizawa

JOURNAL OF PEPTIDE SCIENCE 8(9) 521-528 2002年9月
Chum salmon trypsin-catalyzed preferential formation of peptides containing D-amino acid

H Sekizaki, K Itoh, E Toyota, K Tanizawa

AMINO ACIDS 21(2) 175-184 2001年
X-ray crystallographic analyses of complexes between bovine beta-trypsin and Schiff base copper(II) or iron(III) chelates

E Toyota, KKS Ng, H Sekizaki, K Itoh, K Tanizawa, MNG James

JOURNAL OF MOLECULAR BIOLOGY 305(3) 471-479 2001年1月
Chum salmon trypsin-catalyzed peptide synthesis with inverse substrate as acyl donor components at low temperature

J. Mol. Catal. B : Enzym 11(1) 23-28 2000年
Anionic trypsin from chum salmon : activity with p-amidinophenyl ester and comparison with bovine and<Streptomyces griseus>trypsin

Comp. Biochem. Physiol. B 127(3) 337-346 2000年
Trypsin-catalyzed peptide synthesis with m-guanidinophenyl and m-(guanidinomethyl)phenyl esters as acyl donor component

Amino Acids 17(3) 285-292 1999年
Application of various inverse substrates to thrombin-catalyzed peptide synthesis

Chem. Pharm. Bull. 47(3) 444-447 1999年
The structural requirement for an inverse substrate for enzymatic peptide synthesis : position isomers of guanidinonaphthyl esters as an acyl donor component

Haruo SEKIZAKI, Kunihiko ITOH, Eiko TOYOTA, Kazutaka TANIZAWA

Chem. Pharm. Bull. 47(1) 104-110 1999年
Application of Schiff base copper(II)and Iron(III) chelates to site-specific cleavage of a trypsin

Eiko TOYOTA, Hiromitsu MIYAZAKI, Kunihiko ITOH, Haruo SEKIZAKI, Kazutaka TANIZAWA

Chem. Pharm. Bull. 47(1) 116-119 1999年
Enzymatic peptide synthesis with p-guanidinophenyl and p-(guanidinomethyl)phenyl esters as acyl donors

Haruo SEKIZAKI, Kunihiko ITHO, Eiko TOYOTA, Kazutaka TANIZAWA

Chem. Pharm. Bull. 46(5) 846-849 1998年
Enzymatic coupling of alpha,alpha-dialkyl amino acids using inverse substrates as acyl donors

H Sekizaki, K Itoh, E Toyota, K Tanizawa

TETRAHEDRON LETTERS 38(10) 1777-1780 1997年3月
Methyltrypsin-catalyzed peptide coupling : comparison of alkyl ester and guanidinophenyl ester delivatives as acyl donor component

Bioorg. Chem. 25(5) 6, 307-319 1997年
Trypsin-catalyzed peptide synthesis with various p-guanidinophenyl esters as acyl donors.

Haruo SEKIZAKI, Kunihiko ITOH, Eiko TOYOTA, Kazutaka TANIZAWA

Chem. Pharm. Bull. 44(8) 1585-1587 1996年
Synthesis and tryptic hydrolysis of p-guanidinophenyl esters derived from amino acids and peptides

Haruo SEKIZAKI, Kunihiko ITOH, Eiko TOYOTA, Kazutaka TANIZAWA

Chem. Pharm. Bull. 44(8) 1577-1579 1996年
Application of spontaneous Schiff base copper chelates formation process to the design of a trypsin inhibitor

Eiko TOYOTA, Chisako CHINEN, Haruo SEKIZAKI, Kunihiko ITOH, Kazutaka TANIZAWA

Chem. Pharm. Bull. 44(5) 1104-1106 1996年
Chromatographic separation of diastereomeric Schiff base copper(II), nickel(II), and zinc(II) chelates from α-amino acids racemates

Bioorg. Chem. 24(2) 150-158 1996年

もっとみる

所属学協会

6

共同研究・競争的資金等の研究課題

2

天然高分子を利用した易服用性製剤の設計

2005年
Development of oral sustained liquid formulation

2005年