岡澤秀樹 (Hideki Okazawa) - マイポータル

基本情報

所属: 旧所属群馬大学生体調節研究所病態制御部門助教

学位: 博士(医学)(神戸大学)

J-GLOBAL ID: 200901030882322747
researchmap会員ID: 1000241666

研究キーワード

研究分野

MISC

Negative regulation by SHPS-1 of Toll-like receptor-dependent proinflammatory cytokine production in macrophages

Atsuko Miyake, Yoji Murata, Hideki Okazawa, Hiroshi Ikeda, Yuriko Niwayama, Hiroshi Ohnishi, Yukio Hirata, Takashi Matozaki

GENES TO CELLS 13(2) 209-219 2008年2月
Regulation by Src homology 2 domain-containing protein tyrosine phosphatase substrate-1 of alpha-galactosylceramide-induced antimetastatic activity and Th1 and Th2 responses of NKT cells

Jun Okajo, Yoriaki Kaneko, Yoji Murata, Takeshi Tomizawa, Chie Okuzawa, Yasuyuki Saito, Yuka Kaneko, Tomomi Ishikawa-Sekigami, Hideki Okazawa, Hiroshi Ohnishi …

JOURNAL OF IMMUNOLOGY 178(10) 6164-6172 2007年5月
Resistance to experimental autoimmune encephalomyelitis and impaired T cell priming by dendritic cells in SHPS-1 mutant mice

Tomizawa T, Kaneko Y, Kaneko Y, Saito Y, Ohnishi H, Okajo J, Okuzawa C, Ishikawa-Sekigami T, Murata Y, Okazawa H …

J Immunol 179(2) 869-877 2007年
Resistance to experimental autoimmune encephalomyelitis and impaired T cell priming by dendritic cells in SHPS-1 mutant mice

Tomizawa T, Kaneko Y, Kaneko Y, Saito Y, Ohnishi H, Okajo J, Okuzawa C, Ishikawa-Sekigami T, Murata Y, Okazawa H …

J Immunol 179(2) 869-877 2007年
Src homology 2 domain-containing protein tyrosine phosphatase substrate 1 regulates the induction of Langerhans cell maturation

Atsushi Fukunaga, Hiroshi Nagai, Xijun Yu, Shuntaro Oniki, Hideki Okazawa, Sei-ichiro Motegi, Ryuji Suzuki, Nakayuki Honma, Takashi Matozaki, Chikako Nishigori …

EUROPEAN JOURNAL OF IMMUNOLOGY 36(12) 3216-3226 2006年12月
CD47 promotes neuronal development through Src- and FRG/Vav2-mediated activation of Rac and Cdc42

Takaaki Murata, Hiroshi Ohnishi, Hideki Okazawa, Yoji Murata, Shinya Kusakari, Yuriko Hayashi, Motoaki Miyashita, Hiroshi Itoh, Per-Arne Oldenborg, Nobuhiko Furuya …

JOURNAL OF NEUROSCIENCE 26(48) 12397-12407 2006年11月
CD47 regulation of epithelial cell spreading and migration, and its signal transduction

Masahiko Shinohara, Naoko Ohyama, Yoji Murata, Hideki Okazawa, Hiroshi Ohnishi, Osamu Ishikawa, Takashi Matozaki

CANCER SCIENCE 97(9) 889-895 2006年9月
Enhanced phagocytosis of CD47-deficient red blood cells by splenic macrophages requires SHPS-1

Tomomi Ishikawa-Sekigami, Yoriaki Kaneko, Yasuyuki Saito, Yoji Murata, Hideki Okazawa, Hiroshi Ohnishi, Per-Arne Oldenborg, Yoshihisa Nojima, Takashi Matozaki

Biochemical and Biophysical Research Communications 343(4) 1197-1200 2006年5月19日
SHPS-1 promotes the survival of circulating erythrocytes through inhibition of phagocytosis by splenic macrophages

T Ishikawa-Sekigami, Y Kaneko, H Okazawa, T Tomizawa, J Okajo, Y Saito, C Okuzawa, M Sugawara-Yokoo, L Nishiyama, H Ohnishi …

BLOOD 107(1) 341-348 2006年1月
Mutational Analysis of the Mechanism of Negative Regulation by SHPS-1 of Phagocytosis in Macrophages.

Ikeda H, Okazawa H, Ohnishi H, Murata Y, Oldenborg PA, Matozaki T

Journal of Immunology 117(5) 3123-3132 2006年
CD47 regulation of epithelial cell spreading and migration, and its siganl transduction

Shinohara M, Ohyama N, Murata Y, Okazawa H, Ohnishi H, Ishikawa O, Matozaki T

Cancer Science 97(9) 889-895 2006年
SHPS-1 promotes the survival of circulating erythrocytes through inhibition of phagocytosis by splenic macrophages

Tomomi Ishikawa-Sekigami, Yoriaki Kaneko, Hideki Okazawa, Takeshi Tomizawa, Jun Okajo, Yasuyuki Saito, Chie Okuzawa, Minako Sugawara-Yokoo, Uichi Nishiyama, Hiroshi Ohnishi …

Blood 107(1) 341-348 2006年1月1日
Mutational Analysis of the Mechanism of Negative Regulation by SHPS-1 of Phagocytosis in Macrophages.

Ikeda H, Okazawa H, Ohnishi H, Murata Y, Oldenborg PA, Matozaki T

Journal of Immunology 117(5) 3123-3132 2006年
Differential localization of Src homology 2 domain-containing protein tyrosine phosphatase substrate-1 and CD47 and its molecular mechanisms in cultured hippocampal neurons

H Ohnishi, Y Kaneko, H Okazawa, M Miyashita, R Sato, A Hayashi, K Tada, S Nagata, M Takahashi, T Matozaki

JOURNAL OF NEUROSCIENCE 25(10) 2702-2711 2005年3月
Negative regulation of phagocytosis in macrophages by the CD47-SHPS-1 system

H Okazawa, SI Motegi, N Ohyama, H Ohnishi, T Tomizawa, Y Kaneko, PA Oldenborg, O Ishikawa, T Matozaki

JOURNAL OF IMMUNOLOGY 174(4) 2004-2011 2005年2月
Promotion of neurite and filopodium formation by CD47: Roles of integrins, Rac, and Cdc42

M Miyashita, H Ohnishi, H Okazawa, H Tomonaga, A Hayashi, TT Fujimoto, N Furuya, T Matozaki

MOLECULAR BIOLOGY OF THE CELL 15(8) 3950-3963 2004年8月
Ectodomain shedding of SHPS-1 and its role in regulation of cell migration

H Ohnishi, H Kobayashi, H Okazawa, Y Ohe, K Tomizawa, R Sato, T Matozaki

JOURNAL OF BIOLOGICAL CHEMISTRY 279(27) 27878-27887 2004年7月
Positive regulation of phagocytosis by SIRP beta and its signaling mechanism in macrophages

A Hayashi, H Ohnishi, H Okazawa, S Nakazawa, H Ikeda, S Motegi, N Aoki, S Kimura, M Mikuni, T Matozaki

JOURNAL OF BIOLOGICAL CHEMISTRY 279(28) 29450-29460 2004年7月
Src homology 2 domain-containing protein tyrosine phosphatase substrate 1 regulates the migration of Langerhans cells from the epidermis to draining lymph nodes

A Fukunaga, H Nagai, T Noguchi, H Okazawa, T Matozaki, XJ Yu, CF Lagenaur, N Honma, M Ichihashi, M Kasuga …

JOURNAL OF IMMUNOLOGY 172(7) 4091-4099 2004年4月
新規細胞間シグナル伝達システムCD47-SHPS-1系の機能

的崎尚, 岡澤秀樹, 大西浩史

細胞工学 23(5) 546-550 2004年

もっとみる

書籍等出版物

日本遺伝子治療学会編遺伝子治療開発研究ハンドブック

NTS 1999年

所属学協会

共同研究・競争的資金等の研究課題

細胞間情報伝達

補助金 2001年
cell signaling

Grants and Funding 2001年

岡澤秀樹

基本情報

研究キーワード

研究分野

MISC

書籍等出版物

所属学協会

共同研究・競争的資金等の研究課題

産業財産権

メニュー