渡邊賢一 (Kenichi Watanabe) - マイポータル

基本情報

所属: 新潟大学医歯学総合研究科特任教授

学位: 医学博士（新潟大学、医学部。新大医博第726號）, 薬学博士（静岡県立大学、薬学部。論博第45号）(新潟大学)

J-GLOBAL ID: 200901053252666499
researchmap会員ID: 1000243134

研究キーワード

研究分野

ライフサイエンス / 内科学一般 /

論文

Combination of imeglimin and resistance exercise improves mitochondrial function and glucose metabolism in skeletal muscles.

Hajime Ishiguro, Keitaro Minato, Keiya Iwaasa, Sijia Wu, Guo Antao, Takumu Tsuchida, Tatsuya Suwabe, Takayuki Katagiri, Hiroshi Suzuki, Masayoshi Masuko …

Journal of diabetes and its complications 39(10) 109145-109145 2025年10月
糖尿病モデルマウスにおけるトリュフ抽出物の血糖上昇抑制作用の検討

岩浅啓矢, 鈴木浩史, 石黒創, 渡辺賢一, 郭安韜, 小西徹也, 井口晃徳, 中川沙織, 曽根博仁

機能性食品と薬理栄養 18(3) 201-201 2024年12月
Basidiomycetes-X, an edible mushroom, alleviates the development of atopic dermatitis in NC/Nga mouse model.

Watanabe K, Karuppagounder V, Sreedhar R, Kandasamy G, Harima M, Velayutham R, Arumugam S

Experimental and molecular pathology 105(3) 322-327 2018年12月査読有り
From a Ph.D. thesis: Understanding the past, predicting the future

Kenichi Watanabe

Yakugaku Zasshi 138(2) 211-219 2018年査読有り
Small molecule disruption of G protein βγ subunit signaling reprograms human macrophage phenotype and prevents autoimmune myocarditis in rats.

Karuppagounder V, Bajpai A, Meng S, Arumugam S, Sreedhar R, Giridharan VV, Guha A, Bhimaraj A, Youker KA, Palaniyandi SS …

PloS one 13(7) e0200697 2018年査読有り
Comparative evaluation of torasemide and spironolactone on adverse cardiac remodeling in a rat model of dilated cardiomyopathy

Somasundaram Arumugam, Remya Sreedhar, Vengadeshprabhu Karuppagounder, Meilei Harima, Masahiko Nakamura, Hiroshi Suzuki, Hirohito Sone, Kenichi Watanabe

CARDIOVASCULAR THERAPEUTICS 35(5) 2017年10月査読有り
Curcumin reduces the risk of chronic kidney damage in mice with nonalcoholic steatohepatitis by modulating endoplasmic reticulum stress and MAPK signaling

Rejina Afrin, Somasundaram Arumugam, Md. Azizur Rahman, Vengadeshprabhu Karuppagounder, Meilei Harima, Hiroshi Suzuki, Shizuka Miyashita, Kenji Suzuki, Kazuyuki Ueno, Hiroyuki Yoneyama …

INTERNATIONAL IMMUNOPHARMACOLOGY 49 161-167 2017年8月査読有り
Role of 14-3-3η protein on cardiac fatty acid metabolism and macrophage polarization after high fat diet induced type 2 diabetes mellitus.

Sreedhar R, Arumugam S, Thandavarayan RA, Karuppagounder V, Koga Y, Nakamura T, Harima M, Watanabe K

The international journal of biochemistry & cell biology 88 92-99 2017年7月査読有り
The senescence accelerated mouse prone 8 (SAMP8): A novel murine model for cardiac aging

Vengadeshprabhu Karuppagounder, Somasundaram Arumugam, Sahana Suresh Babu, Suresh S. Palaniyandi, Kenichi Watanabe, John P. Cooke, Rajarajan A. Thandavarayan

AGEING RESEARCH REVIEWS 35 291-296 2017年5月査読有り
Comparative effects of torasemide and furosemide on gap junction proteins and cardiac fibrosis in a rat model of dilated cardiomyopathy

Kenichi Watanabe, Remya Sreedhar, Rajarajan A. Thandavarayan, Vengadeshprabhu Karuppagounder, Vijayasree V. Giridharan, Shanish Antony, Meilei Harima, Masahiko Nakamura, Kenji Suzuki, Hiroshi Suzuki …

BIOFACTORS 43(2) 187-194 2017年3月査読有り
Curcumin ameliorates liver damage and progression of NASH in NASH-HCC mouse model possibly by modulating HMGB1-NF-κB translocation.

Afrin R, Arumugam S, Rahman A, Wahed MI, Karuppagounder V, Harima M, Suzuki H, Miyashita S, Suzuki K, Yoneyama H …

International immunopharmacology 44 174-182 2017年3月査読有り
Phase 1 Clinical Study of siRNA Targeting Carbohydrate Sulphotransferase 15 in Crohn's Disease Patients with Active Mucosal Lesions

Kenji Suzuki, Junji Yokoyama, Yusuke Kawauchi, Yutaka Honda, Hiroki Sato, Yutaka Aoyagi, Shuji Terai, Kazuichi Okazaki, Yasuo Suzuki, Yukinori Sameshima …

JOURNAL OF CROHNS & COLITIS 11(2) 221-228 2017年2月査読有り
Le Carbone, a charcoal supplement, modulates DSS-induced acute colitis in mice through activation of AMPKα and downregulation of STAT3 and caspase 3 dependent apoptotic pathways.

Afrin MR, Arumugam S, Rahman MA, Karuppagounder V, Sreedhar R, Harima M, Suzuki H, Nakamura T, Miyashita S, Suzuki K …

International immunopharmacology 43 70-78 2017年2月査読有り
Tiny molecule, big power: Multi-target approach for curcumin in diabetic cardiomyopathy

Vengadeshprabhu Karuppagounder, Somasundaram Arumugam, Vijayasree V. Giridharan, Remya Sreedhar, Rajendran J. C. Bose, Jyothi Vanama, Suresh S. Palaniyandi, Tetsuya Konishi, Kenichi Watanabe, Rajarajan A. Thandavarayan

NUTRITION 34 47-54 2017年2月査読有り
Erratum to “Hypothalamic glucagon signaling in fasting hypoglycemia” (Life Sci. (2016) 153 (118–123))

Vigneshwaran Pitchaimani, Somasundaram Arumugam, Rajarajan Amirthalingam Thandavarayan, Vengadeshprabhu Karuppagounder, Mst. Rejina Afrin, Remya Sreedhar, Meilei Harima, Hiroshi Suzuki, Shizuka Miyashita, Kenji Suzuki …

Life Sciences 160 1 2016年9月1日査読有り
Fasting time duration modulates the onset of insulin-induced hypoglycemic seizures in mice

Vigneshwaran Pitchaimani, Somasundaram Arumugam, Rajarajan Amirthalingam Thandavarayan, Vengadeshprabhu Karuppagounder, Mst. Rejina Afrin, Remya Sreedhar, Meilei Harima, Hiroshi Suzuki, Shizuka Miyashita, Takashi Nakamura …

EPILEPSY RESEARCH 125(9) 47-51 2016年9月査読有り
Curcumin alleviates renal dysfunction and suppresses inflammation by shifting from M1 to M2 macrophage polarization in daunorubicin induced nephrotoxicity in rats

Vengadeshprabhu Karuppagounder, Somasundaram Arumugam, Rajarajan A. Thandavarayan, Remya Sreedhar, Vijayasree V. Giridharan, Rejina Afrin, Meilei Harima, Shizuki Miyashita, Masanori Hara, Kenji Suzuki …

CYTOKINE 84 1-9 2016年8月査読有り
Role of MAPK-mediated endoplasmic reticulum stress signaling in the heart during aging in senescence-accelerated prone mice

Remya Sreedhar, Vijayasree V. Giridharan, Somasundaram Arumugam, Vengadeshprabhu Karuppagounder, Suresh S. Palaniyandi, Prasanna Krishnamurthy, Joao Quevedo, Kenichi Watanabe, Tetsuya Konishi, Rajarajan A. Thandavarayan

BIOFACTORS 42(4) 368-375 2016年7月査読有り
Pivotal Role of Carbohydrate Sulfotransferase 15 in Fibrosis and Mucosal Healing in Mouse Colitis

Kenji Suzuki, Somasundaram Arumugam, Junji Yokoyama, Yusuke Kawauchi, Yutaka Honda, Hiroki Sato, Yutaka Aoyagi, Shuji Terai, Kazuichi Okazaki, Yasuo Suzuki …

PLOS ONE 11(7) e0158967 2016年7月査読有り
Targeting fatty acid metabolism in heart failure: is it a suitable therapeutic approach?

Somasundaram Arumugam, Remya Sreedhar, Rajarajan A. Thandavarayan, Vengadeshprabhu Karuppagounder, Kenichi Watanabe

DRUG DISCOVERY TODAY 21(6) 1003-1008 2016年6月査読有り

もっとみる

MISC

Blake's pouch cystに伴う水頭症の治療により若年性認知症の改善を認めた糖尿病の1例

種村聡, 山本正彦, 石黒創, 岩永みどり, 松林泰弘, 山田貴穂, 藤原和哉, 渡邊賢一, 曽根博仁

糖尿病 62(7) 441-441 2019年7月
メタ解析からみた糖尿病の心不全発症危険因子としての疫学的エビデンス

児玉暁, 藤原和哉, 石澤正博, 石黒創, 松林泰弘, 岩永みどり, 山田貴穂, 渡辺賢一, 加藤公則, 曽根博仁

日本内科学会雑誌 108(Suppl.) 270-270 2019年2月
Blake’s pouch cystに伴う水頭症の治療により若年性認知症の改善を認めた糖尿病の1例

種村聡, 山本正彦, 石黒創, 岩永みどり, 松林泰弘, 山田貴穂, 藤原和哉, 渡邊賢一, 曽根博仁

糖尿病(Web) 62(7) 2019年
高血圧と機能性食品 GABAと高血圧

渡辺賢一, 鈴木浩史, ARUMUGAM Somasundaram

機能性食品と薬理栄養 11(1) 2017年
Modulation of HMGB1-NF-kappa B translocation by cur cumin treatment ameliorates liver injury in non-alcoholic steatohepatitis-hepatocellular carcinoma mouse model

Rejina Afrin, Somasundaram Arumugam, Md. Azizur Rahman, Vengadeshprabhu Karuppagounder, Meilei Harima, Hiroshi Suzuki, Shizuka Miyashita, Kenji Suzuki, Hiroyuki Yoneyama, Kazuyuki Ueno …

HEPATOLOGY 64 765A-765A 2016年10月
"Hypothalamic glucagon signaling in fasting hypoglycemia" (vol 153, pg 118, 2016)

Vigneshwaran Pitchaimani, Somasundaram Arumugama, Rajarajan Amirthalingam Thandavarayan, Vengadeshprabhu Karuppagounder, Mst. Rejina Afrin, Remya Sreedhar, Meilei Harima, Hiroshi Suzuki, Shizuka Miyashita, Kenji Suzuki …

LIFE SCIENCES 160 1-1 2016年9月
Curcumin Ameliorates Progression of Liver Tumors and Damage through Inhibition of Oxidative Stress, Inflammation, and Fibrosis in Nonalcoholic Steatohepatitis-Hepatocellular Carcinoma Mouse Model

M. S. T. Rejina Afrin, Somasundaram Arumugam, M. D. Azizur Rahman, Vigneshwaran Pitchaimani, Vengadeshprabhu Karuppagounder, Remya Sreedhar, Meilei Harima, Hiroshi Suzuki, Shizuka Miyashita, Kenji Suzuki …

DIABETES 65 A579-A579 2016年6月
心臓集積性標識薬剤(脂肪酸、糖)を用いた糖尿病(1型)における心臓/腎臓の機能評価

高橋俊博, 菊地飛鳥, 上江洲千博, 谷藤貴行, 吉田秀義, 渡辺彩華, Wang Zhijia, 渡辺賢一, 張馬梅蕾, Afrin R …

新潟核医学懇話会記録集 43 10p 2016年4月9日
【糖尿病と機能性食品】脂質摂取と糖尿病

鈴木浩史, 渡辺賢一, 曽根博仁

機能性食品と薬理栄養 9(3) 131-134 2015年10月
糖尿病性臓器障害の基礎的検討 : 糖尿病性心筋症・腎症と小胞体ストレス (シンポジウム糖尿病の合併症 : 第699回新潟医学会)

渡辺賢一, LAKSHMANAN Arun Prasath, SOETIKNO Vivian, Flori R Sari, Vijayakumar Sukumaran, Vijayasree V Giridharan, Rejina Afrin, Somasundaram Arumugam, Vengadesh Karuppagounder, Rajarajan A Thandavarayan …

新潟医学会雑誌 129(7) 354-363 2015年7月
Curcumin Decreases Renal and Liver Triglyceride Accumulation through AMPK-SREBP Signaling Pathway in Streptozotocin-induced Type 1 Diabetic Rats

Hiroshi Suzuki, Vigneshwaran Pitchaimani, Somasundaran Arumugam, Rajarajan A. Thandavarayan, Vengadeshprabhu Karuppagounder, Remya Sreeedhar, Meilei Harima, Shizuka Miyashita, Mayumi Nomoto, Kenji Suzuki …

DIABETES 64 A146-A146 2015年6月
Brain Metabolic Alterations in Moderate and Severe Hypoglycemia of Mice

Hiroshi Suzuki, Vigneshwaran Pitchaimani, Somasundaran Arumugam, Rajarajan A. Thandavarayan, Vengadeshprabhu Karuppagounder, Remya Sreeedhar, Meilei Harima, Shizuka Miyashita, Mayumi Nomoto, Kenji Suzuki …

DIABETES 64 A107-A107 2015年6月
心不全ラットにおけるPV(心臓脂肪酸代謝機能改善予想薬)の薬効評価 : 心臓集積性標識薬剤を用いた検討

渡辺彩華, 林綾乃, 高橋俊博, 飯尾菜美子, 稲川浩平, 宮尾歩美, 川島友彰, 吉田秀義, 渡辺賢一, 張馬梅蕾 …

新潟核医学懇話会記録集 42 6p 2015年5月16日
Dominant Negative 14-3-3 Protein Exacerbates Cardiac Dysfunction by Suppressing Cardiac Regeneration After Coronary Artery Ligation in Mice

Rajarajan Amirthalingam Thandavarayan, Somasundaram Arumugam, Vigneshwaran Pitchaimani, Vengadeshprabhu Karuppa Gounder, Vijayasree V. Giridharan, Remya Sreedhar, Meilei Harima, Darukeshwara Joladarashi, Kenji Suzuki, Kenichi Watanabe …

CIRCULATION 130 2014年11月
Schisandrin B Prevents Doxorubicin Induced Cardiac Dysfunction by Modulation of DNA Damage, Oxidative Stress and Inflammation Through Inhibition of MAPK/p53 Signaling

Tetsuya Konishi, Rajarajan A. Thandavarayan, Vijayasree V. Giridharan, Somasundaram Arunnugam, Kenichi Watanabe

FREE RADICAL BIOLOGY AND MEDICINE 51 S52-S52 2011年11月
Diabetic cardiomyopathy and oxidative stress: Role of antioxidants

Rajarajan A. Thandavarayan, Vijayasree V. Giridharan, Kenichi Watanabe, Tetsuya Konishi

Cardiovascular and Hematological Agents in Medicinal Chemistry 9(4) 225-230 2011年10月
Inactivation of p38 alpha Mitogen-activated Protein Kinase Attenuates Doxorubicin-induced Cardiac Oxidative DNA Damage, Apoptosis and Dysfunction

Rajarajan A. Thandavarayan, Vijaysree V. Giridharan, Kenichi Watanabe, Hiroshi Nishida, Hari N. Bhilwade, Shinji Sato, Tetsuya Konishi

FREE RADICAL BIOLOGY AND MEDICINE 49 S30-S30 2010年
Role of 14-3-3 protein and oxidative stress in diabetic cardiomyopathy

K. Watanabe, R. A. Thandavarayan, N. Gurusamy, S. Zhang, A. J. Muslin, K. Suzuki, H. Tachikawa, M. Kodama, Y. Aizawa

ACTA PHYSIOLOGICA HUNGARICA 96(3) 277-287 2009年9月
Fatty add oxidation is restored regardless of impaired uptake in the compensation period of rat chronically failing heart

Hitoshi Tachikawa, Makoto Kodama, Kenichi Watanabe, Toshihiro Takahashi, Masahiro Ito, Haruo Hanawa, Yoshifusa Aizawa

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY 45 S12-S13 2008年10月
Mast cells, the allergic responders, a target of heart failure therapy?

Suresh S. Palaniyandi, Kenichi Watanabe, Dana Mochly-Rosen

JOURNAL OF CARDIAC FAILURE 14(6) S1-S1 2008年8月

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渡邊賢一

基本情報

研究キーワード

研究分野

論文

MISC

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