TONOZUKA Takashi

J-GLOBAL         Last updated: Mar 29, 2019 at 09:44
 
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Name
TONOZUKA Takashi
URL
http://web.tuat.ac.jp/~seika/
Affiliation
Tokyo University of Agriculture and Technology
Section
Institute of Agriculture, Division of Applied Biological Chemistry
Job title
Professor
ORCID ID
0000-0002-5422-7548

Research Areas

 
 

Awards & Honors

 
Jun 2012
"Comparison of the structural changes in two cellobiohydrolases, CcCel6A and CcCel6C, from Coprinopsis cinerea", Molecular Enzymology Virtual Issue, FEBS Journal
Winner: Tonozuka Takashi
 
Sep 2008
"Study on structure and function of enzymes acting on pullulan and related saccharides", Distinguished Young Scientist Award, Japanese Society of Applied Glycoscience
Winner: Tonozuka Takashi
 
Jun 2006
"Crystal structure of isopullulanase and elucidation of its reaction mechanism", Research encouragement award, Amano Enzyme
 

Published Papers

 
Kozono T, Tadahira K, Okumura W, Itai N, Tamura-Nakano M, Dohi T, Tonozuka T, Nishikawa A
Journal of Biochemistry   164(4) 303-311   Oct 2018
Tadashi Fujii, Takumi Tochio, Katsuaki Hirano, Keisuke Tamura, Takashi Tonozuka
Biosci. Biotechnol. Biochem.   82(9) 1599-1605   Jun 2018
Tonozuka, T., Nihira, T., Mizuno, M., Nishikawa, A. and Kamitori, S.
Amylase (De Gruyter)   2 1-10   Mar 2018   [Refereed]
Itai Nao, Shimazu Tsukasa, Kimura Takayuki, Ibe Issei, Yamashita Ryo, Kaburagi Yasushi, Dohi Taeko, Tonozuka Takashi, Takao Toshifumi, Nishikawa Atsushi
Plos One   13(11)    2018   [Refereed]
Nagaya, Mika; Kimura, Miyoko; Gozu, Yoshifumi; Sato, Shona; Hirano, Katsuaki; Tochio, Takumi; Nishikawa, Atsushi; Tonozuka, Takashi
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY   81(9) 1786-1795   2017   [Refereed]
-Fructofuranosidases belonging to glycoside hydrolase family (GH) 32 are enzymes that hydrolyze sucrose. Some GH32 enzymes also catalyze transfructosylation to produce fructooligosaccharides. We found that Aspergillus kawachii IFO 4308 -fructofura...
Tonozuka, Takashi; Tanaka, Yutaro; Okuyama, Shunsaku; Miyazaki, Takatsugu; Nishikawa, Atsushi; Yoshida, Makoto
APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY   181(2) 511-525   Feb 2017   [Refereed]
alpha-l-Arabinofuranosidases, belonging to the glycoside hydrolase family (GH) 62, hydrolyze the alpha-1,2- or alpha-1,3-bond to liberate l-arabinofuranose from the xylan backbone. Here, we determined the structure of the C-terminal catalytic doma...
Miyazaki, T.,  Nishikawa, A. and  Tonozuka, T.  
J. Struct. Biol.   196(3) 479-486   Dec 2016
Gozu, Y., Ishizaki, Y., Hosoyama, Y., Miyazaki, T., Nishikawa, A. and Tonozuka, T.
Biosci. Biotechnol. Biochem.   80(8) 1562-1567   Aug 2016   [Refereed]
Mori, M., Ichikawa, M., Kiguchi, Y., Miyazaki, T., Hattori, M., Nishikawa, A. and Tonozuka, T.
J. Appl. Glycosci.   63(1) 7-11   Feb 2016   [Refereed]
Okazawa, Y., Miyazaki, T., Yokoi, G., Ishizaki, Y., Nishikawa, A. and Tonozuka, T.
J. Biol. Chem.   290(43) 26339-26349   Oct 2015   [Refereed]
Miyazaki, T., Ishizaki, Y., Ichikawa, M., Nishikawa, A., and Tonozuka, T.
Biochem. J.   469(1) 145-158   Jul 2015   [Refereed]
Takagi, E., Hatada, Y., Akita. M., Ohta. Y., Yokoi. G., Miyazaki. T., Nishikawa. A. and Tonozuka T.
Biosci. Biotechnol. Biochem.   79(4) 625-632   Apr 2015   [Refereed]
Miyazaki, T., Ichikawa, M., Iino, H., Nishikawa, A. and Tonozuka, T.
J. Struct. Biol.   190(1) 21-30   Apr 2015   [Refereed]
Miyazaki, T., Yashiro, H., Nishikawa, A. and Tonozuka, T.
J. Biochem.   157(4) 225-234   Apr 2015   [Refereed]
Ohta, Y., Hatada, Y., Hidaka, Y., Shimane, Y., Usui, K., Ito, T., Fujita, K., Yokoi, G., Mori, M., Sato, S., Miyazaki, T., Nishikawa, A. and Tonozuka, T.
Appl. Microbiol. Biotechnol.   98 6667-6677   Aug 2014   [Refereed]
Iwasa, C., Tonozuka, T., Shinoda, M., Sagane, Y., Niwa, K., Watanabe, T., Yoshida, H., Kamitori, S., Takao, T., Oguma, K. and Nishikawa, A.
Acta Crystallogr. Sect. F   70 64-67   Jan 2014
Miyazaki, T., Ichikawa, M., Yokoi, G., Kitaoka, M., Mori, H., Kitano, Y., Nishikawa, A. and Tonozuka, T.
FEBS J.   280 4560-4571   Sep 2013   [Refereed]
Miyazaki, T., Yoshida, M., Tamura, M., Tanaka, Y., Umezawa, K., Nishikawa, A. and Tonozuka, T.
FEBS Lett.   587 2193-2198   Jul 2013   [Refereed]
宮崎剛亜、西河淳、殿塚隆史
応用糖質科学   3(2) 151-158   May 2013   [Refereed]
Tonozuka, T., Tamaki, A., Yokoi, G., Miyazaki, T., Ichikawa, M., Nishikawa, A., Ohta, Y., Hidaka, Y., Katayama, K., Hatada, Y., Ito, T. and Fujita, K.
Enzyme Microb. Technol.   51 359-365   Oct 2012   [Refereed]

Books etc

 
Traffic of Botulinum toxin complex: the crystal structure and the role of toxin complex
Tonozuka, T., Oguma, K. and Nishikawa, A. (Part:Joint Work)
"Glycoscience: Biology and Medicine" (Endo, T., Seeberger, P.H., Hart, G.W., Wong, C.-H. and Taniguchi, N., eds.), Springer   Jan 2015   
Enzymes for cellulosic biomass conversion
Tonozuka, T., Yoshida, M. and Takeuchi, M. (Part:Joint Work)
"Research Approaches to Sustainable Biomass Systems" (Tojo, S. and Hirasawa, T., eds.), Academic Press Elsevier   Sep 2013   
Crystal structure of the pullulan-hydrolyzing alpha-amylase from Thermoactinomyces vulgaris R-47, and manipulation of the substrate specificities
Tonozuka, T. and Sakano, Y. (Part:Joint Work)
"Recent Advances in Carbohydrate Bioengineering" (Gilbert H.J., Henrissat, B. and Svensson, B., eds.), The Royal Society of Chemistry   Jun 1999   

Conference Activities & Talks

 
担子菌Coprinopsis cinerea由来CcGH131Bと各種リガンドとのX線結晶構造解析
石川涼一、吉田誠、砂川直輝、五十嵐圭日子、西河淳、殿塚隆史
日本結晶学会   9 Nov 2018   日本結晶学会
Flavobacterium johnsoniae由来GH31デキストラナーゼFjDex31A改変酵素の性質解析
堤賢太、郷津佳史、西河淳、殿塚隆史
日本応用糖質科学会   10 Sep 2018   日本応用糖質科学会
プルラン分解α-アミラーゼTVA Iの改変酵素におけるドメインBのコンフォメーション変化
殿塚隆史, 西河淳, 神鳥成弘
日本応用糖質科学会   10 Sep 2018   日本応用糖質科学会
担子菌のGH131に属する酵素の立体構造と機能の解析 [Invited]
殿塚隆史
セルラーゼ研究会   13 Jul 2018   セルラーゼ研究会
Aspergillus kawachii由来β-フルクトフラノシダーゼの改変による1-ケストース生産能向上と改変酵素の構造解析
長屋美香、平野勝紹、藤井匡、栃尾巧、西河淳、殿塚隆史
日本農芸化学会   16 Mar 2018   日本農芸化学会

Works

 
CAZypedia, Glycoside Hydrolase Family 49 http://www.cazypedia.org/
The Others   2010 - 2010

Research Grants & Projects

 
担子菌のファミリー131に属する二種類のタンパク質の構造と機能の解明
Project Year: 2016 - 2018
ファミリー131に属する機能未知酵素がバイオマス分解に果たす役割の解明
Project Year: 2014 - 2015
糖鎖に作用する機能未知グリコシダーゼの構造解析とオリゴ糖創出への応用
Project Year: 2011 - 2013
糖鎖に作用するグルコシダーゼの構造と機能の解明
Project Year: 2008 - 2010
機能性オリゴ糖製造酵素の新規な固定化法の開発
独立行政法人科学技術振興機構: 
Project Year: Nov 2012 - Mar 2013