2013年4月
Correlations between alveolar bone microstructure and bone turnover markers in pre- and post-menopausal women.
Oral surgery, oral medicine, oral pathology and oral radiology
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- 巻
- 115
- 号
- 4
- 開始ページ
- e12-9
- 終了ページ
- E19
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1016/j.oooo.2011.10.028
- 出版者・発行元
- ELSEVIER SCIENCE INC
OBJECTIVE: Alveolar cancellous bone biopsy samples were extracted during dental implant preparation for investigating microstructural changes due to menopause and relationships between these changes and bone turnover markers. STUDY DESIGN: Subjects were 18 women receiving mandibular implants: premenopausal (n = 5), early postmenopausal (≤5 years; n = 3), and late postmenopausal (>5 years; n = 10). Bone turnover markers were measured and the samples analyzed using microscopic computerized tomography and 3-dimensional bone morphometry. RESULTS: The alveolar bone volume was significantly less in late postmenopausal women than in premenopausal ones. The trabeculae in early postmenopausal women were more separated and rod-like than in premenopausal ones (P < .05). Each alveolar bone parameter was significantly (P < .05) related to at least 1 bone turnover marker. CONCLUSIONS: Alveolar cancellous bone structure begins changing even in early postmenopausal women, and this structure varies in close relationship to bone turnover markers.
- リンク情報
- ID情報
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- DOI : 10.1016/j.oooo.2011.10.028
- ISSN : 2212-4403
- PubMed ID : 22710077
- Web of Science ID : WOS:000316666700003