2008年4月
Expedient synthetic transformation of ptychantins into forskolin
SYNLETT
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- 巻
- 号
- 6
- 開始ページ
- 929
- 終了ページ
- 931
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1055/s-2008-1042930
- 出版者・発行元
- GEORG THIEME VERLAG KG
Forskolin has been synthesized in 11 steps with a 17% overall yield from ptychantins A and B, which have been isolated from the liverwort Ptychanthus striatus in good yield. The I a-hydroxy group was furnished by stereoselective reduction of the corresponding carbonyl group by sodium cyanoborohydride. The 9 alpha-hydroxy group was introduced stereoselectively by epoxidation of Delta(9,11)-enol ether.
- リンク情報
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- DOI
- https://doi.org/10.1055/s-2008-1042930
- Web of Science
- https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000255342400031&DestApp=WOS_CPL
- URL
- https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=42049118936&origin=inward
- ID情報
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- DOI : 10.1055/s-2008-1042930
- ISSN : 0936-5214
- Web of Science ID : WOS:000255342400031