論文

査読有り 国際誌
2022年8月11日

Impact of Pelvic Fracture Sites on Fibrinogen Depletion in Patients with Blunt Trauma: A Single-Center Cohort Study.

Journal of clinical medicine
  • Mayuko Kunii
  • ,
  • Shunichiro Nakao
  • ,
  • Yuko Nakagawa
  • ,
  • Junya Shimazaki
  • ,
  • Hiroshi Ogura

11
16
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.3390/jcm11164689

BACKGROUND: We aimed to examine the association of pelvic fracture sites with the minimum fibrinogen level within 24 h after hospital arrival. METHODS: We conducted a single-center cohort study using health records review. We included patients with pelvic fractures transported by ambulance to a tertiary-care hospital from January 2012 to December 2018 and excluded those transported from other hospitals or aged younger than 16 years. The pelvic fracture was diagnosed and confirmed by trauma surgeons and/or radiologists. We classified the fracture sites of the pelvis as ilium, pubis, ischium, acetabulum, sacrum, sacroiliac joint diastasis, and pubic symphysis diastasis, and each side was counted separately except for pubic symphysis diastasis. We performed linear regression analysis to evaluate the association between pelvic fracture sites and the minimum fibrinogen level within 24 h of arrival. RESULTS: We analyzed 120 pelvic fracture patients. Their mean age was 47.3 years, and 69 (57.5%) patients were men. The median Injury Severity Score was 24, and in-hospital mortality was 10.8%. The mean minimum fibrinogen level within 24 h of arrival was 171.4 mg/dL. Among pelvic fracture sites, only sacrum fracture was statistically significantly associated with the minimum fibrinogen level within 24 h of arrival (estimate, -34.5; 95% CI, -58.6 to -10.4; p = 0.005). CONCLUSIONS: Fracture of the sacrum in patients with pelvic fracture was associated with lower minimum fibrinogen levels within 24 h of hospital arrival and the requirement of blood transfusion.

リンク情報
DOI
https://doi.org/10.3390/jcm11164689
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/36012927
PubMed Central
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9409758
ID情報
  • DOI : 10.3390/jcm11164689
  • PubMed ID : 36012927
  • PubMed Central 記事ID : PMC9409758

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