2021年
ron-catalysed enantioselective carbometalation of azabicycloalkenes
Chem. Commun
- 巻
- 57
- 号
- 57
- 開始ページ
- 6975
- 終了ページ
- 6978
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1039/d1cc02387j
- 出版者・発行元
- ROYAL SOC CHEMISTRY
The first enantioselective carbometalation reaction of azabicycloalkenes has been achieved by iron catalysis to in situ form optically active organozinc intermediates, which are amenable to further synthetic elaborations. The observed chiral induction, along with the DFT and XAS analyses, reveals the direct coordination of the chiral phosphine ligand to the iron centre during the carbon-carbon and carbon-metal bond forming step. This new class of iron-catalysed asymmetric reaction will contribute to the synthesis and production of bioactive molecules.
- リンク情報
- ID情報
-
- DOI : 10.1039/d1cc02387j
- ISSN : 1359-7345
- eISSN : 1364-548X
- Web of Science ID : WOS:000669479100001