2015年
Discrimination of Target Proteins Using Arrayed Fluorescent Liposomes Incorporated with Cholesterol by Principal Component Analysis
2015 IEEE SENSORS
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- 開始ページ
- 1231
- 終了ページ
- 1234
- 記述言語
- 英語
- 掲載種別
- 研究論文(国際会議プロシーディングス)
- DOI
- 10.1109/ICSENS.2015.7370493
- 出版者・発行元
- IEEE
A bio array sensing system is newly composed utilizing different phospholipid liposomes encapsulating fluorescent molecules. We have confirmed a high output intensity of fluorescence emission due to the characteristics dependent on the concentration of fluorescent molecules when the fluorescent molecules leak from inside of the liposome through perturbed lipid membrane. After measuring a whole array image of fluorescence emission output from every element of liposome sensor by a new CMOS imager system, the outputs of fluorescence emission from all the elements were analyzed by a statistical method of principal component analysis (PCA). It was found from obtained PCA plots that different species of proteins with several concentrations were discriminated with high cumulative contribution ratio.
- リンク情報
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- DOI
- https://doi.org/10.1109/ICSENS.2015.7370493
- Web of Science
- https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000380440800324&DestApp=WOS_CPL
- URL
- https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84963607555&origin=inward
- ID情報
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- DOI : 10.1109/ICSENS.2015.7370493
- ISSN : 1930-0395
- SCOPUS ID : 84963607555
- Web of Science ID : WOS:000380440800324