Papers

Nov 1, 2009

Membranomics Research on Interactions between Liposome Membranes with Membrane Chip Analysis

MEMBRANE
  • SHIMANOUCHI Toshinori
  • ,
  • OYAMA Ena
  • ,
  • ISHII Haruyuki
  • ,
  • UMAKOSHI Hiroshi
  • ,
  • KUBOI Ryoichi

Volume
34
Number
6
First page
342
Last page
350
Language
English
Publishing type
DOI
10.5360/membrane.34.342
Publisher
THE MEMBRANE SOCIETY OF JAPAN

The liposome immobilized on indium tin–oxide (ITO) electrode was prepared to evaluate the liposome–liposome interaction to develop "Membrane Chip". Three kinds of standard liposomes entrapping the fluorescence probe, calcein, were used for their immobilization, where the immobilized liposomes show the different characteristics in their phase transition temperature and membrane fluidity. Membrane Chip could give the set of the quantitative information relating to the membrane–membrane interaction. The interaction between three immobilized liposomes and 22 kinds of liposomes as samples was then systematically investigated on a basis of the calcein release from the immobilized liposomes, which could give the information in relation to "Membranome". It was, therefore, found that the Membrane Chip as a means of Membranomics research was effective to evaluate the Membranome information of liposomes.

Link information
DOI
https://doi.org/10.5360/membrane.34.342
CiNii Articles
http://ci.nii.ac.jp/naid/10026876933
CiNii Books
http://ci.nii.ac.jp/ncid/AN0023215X
URL
http://id.ndl.go.jp/bib/10505182
URL
https://jlc.jst.go.jp/DN/JALC/00341564957?from=CiNii
ID information
  • DOI : 10.5360/membrane.34.342
  • ISSN : 0385-1036
  • CiNii Articles ID : 10026876933
  • CiNii Books ID : AN0023215X

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