2014年10月
Contribution of stress wave and cavitation bubble in evaluation of cell-cell adhesion by femtosecond laser-induced impulse
APPLIED PHYSICS A-MATERIALS SCIENCE & PROCESSING
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- 巻
- 117
- 号
- 1
- 開始ページ
- 389
- 終了ページ
- 393
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1007/s00339-014-8498-9
- 出版者・発行元
- SPRINGER
When an intense femtosecond laser is focused in a cell culture medium, shock wave, stress wave, and cavitation bubble are generated at the laser focal point. Cell-cell adhesion can be broken at the cellular level by the impacts of these factors. We have applied this breaking of the adhesion to an estimation of the cell-cell adhesion strength. In this application, it is important to identify which of these factors is the dominant factor that breaks the adhesion. Here we investigated this issue using streptavidin-coated microbeads adhering to a biotin-coated substrate as a mimic of the cell-cell adhesion. The results indicated that the break was induced mainly by the stress wave, not by the impact of the cavitation bubble.
- リンク情報
- ID情報
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- DOI : 10.1007/s00339-014-8498-9
- ISSN : 0947-8396
- eISSN : 1432-0630
- Web of Science ID : WOS:000342281800062