Akio Kazusaka - My portal - researchmap

Profile Information

Affiliation: 助教授, 旧所属北海道大学大学院獣医学研究科獣医学専攻環境獣医科学講座毒性学教室

Degree: (BLANK)

J-GLOBAL ID: 200901015785110884
researchmap Member ID: 1000246792

External link: http://www.hokudai.ac.jp/veteri/

Research Interests

4

Research Areas

2

Education

4

- 1969

Hokkaido University
- 1969

Graduate School, Division of Natural Science, Hokkaido University
- 1964

Faculty of Engineering, Muroran Institute of Technology
- 1964

Faculty of Engineering, Muroran Institute of Technology

Committee Memberships

2

Misc.

68

Inhibitory effects of endogenous dopaminergic neurotoxin, norsalsolinol on dopamine secretion in PC12 rat pheochromocytoma cells

Y Maruyama, H Teraoka, H Iwata, A Kazusaka, S Fujita

NEUROCHEMISTRY INTERNATIONAL, 38(7) 567-572, Jun, 2001
Negative correlation between plasma thyroid hormone levels and chlorinated hydrocarbon levels accumulated in seals from the coast of Hokkaido, Japan

Chiba, I, A Sakakibara, Y Goto, T Isono, Y Yamamoto, H Iwata, S Tanabe, K Shimazaki, F Akahori, A Kazusaka …

ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY, 20(5) 1092-1097, May, 2001
In vivo evidence for accelerated generation of hydroxyl radicals in liver of Long-Evans Cinnamon(LEC)rats with acute hepatitis.

Free Radic Biol Med., 30(5) 547-54, 2001
The antioxidant effect of DL-alpha-lipoic acid on copper-induced acute hepatitis in Long-Evans Cinnamon (LEC) rats

H Yamamoto, T Watanabe, H Mizuno, K Endo, J Fukushige, T Hosokawa, A Kazusaka, S Fujita

FREE RADICAL RESEARCH, 34(1) 69-80, 2001
P450 in wild animals as biomarker of environmental impact.

Biomarkers, 6(1) 13-25, 2001
Norsalsolinol uptake into secretory vesicles via vesicular monoamine transporter and its secretion by membrane depolarization or purinoceptor stimulation in PC12 cells.

Yutaka MARUYAMA, Yuko SUZUKI, Akio KAZUSAKA, Shoichi FUJITA

J Vet Med Sci., 63(5) 493-497, 2001
Uptake of the dopaminergic neurotoxin, norsalsolinol, into PC12 cells via dopamine transporter

Y. Maruyama, Y. Suzuki, A. Kazusaka, S. Fujita

Archives of Toxicology, 75(4) 209-213, 2001
Accumulation of diacylglycerol induced by CCl4-derived radicals in rat liver membrane and its inhibition with radical trapping reagent-FT-IR spectroscopic and HPLC chromatographic observations

Jpn J Vet Res, 47(3-4) 135-44, 2000
Application of FT-IR and ESR spectroscopic techniques to the study of CCl4-induced peroxidation in rat liver microsomes.

Jpn J Vet Res., 47(3-4) 151-4, 2000
FTIR spectroscopic and HPLC chromatographic studies of carbon tetrachloride induced acute hepatitis in rats: Damage in liver phospholipid membrane

S Yoon, A Kazusaka, S Fujita

BIOPOLYMERS, 57(5) 267-271, 2000
Identification of novel cytochrome P450 1A genes from five marine mammal species.

Aquat Toxicol., 5(145-153), 2000
Preventive properties of birch sap against oxidative stress in rats.

Proceedings of the 2 nd International Symposium on Sap Utilization in Bifuka'2000, 149-1153, 2000
Cytochrome P450 isoforms responsible for the N-deethylation and cyclohexane-hydroxylation of NS-21

A Nakamura, T Hirota, A Morino, S Imaoka, Y Funae, Y Yamamoto, T Tasaki, M Masuda, A Kazusaka, S Fujita

XENOBIOTICA, 29(3) 243-252, Mar, 1999
Mechanism of decrease in levels of hepatic P450 isozymes induced by intracerebral endotoxin : independence from sympathetic nervous and adrenocortical systems.

Arch. Toxicol., 73(1) 41-49, 1999
Organochlorine pesticides and polychlorinated biphenyl congeners in wild terrestrial mammals and birds from Chubu region, Japan: Interspecies comparison of the residue levels and compositions

H Hoshi, N Minamoto, H Iwata, K Shiraki, R Tatsukawa, S Tanabe, S Fujita, K Hirai, T Kinjo

CHEMOSPHERE, 36(15) 3211-3221, Jun, 1998
Molecular basis of the Dark Agouti rat drug oxidation polymorphism: Importance of CYP2D1 and CYP2D2

Y Yamamoto, T Tasaki, A Nakamura, H Iwata, A Kazusaka, FJ Gonzalez, S Fujita

PHARMACOGENETICS, 8(1) 73-82, Feb, 1998
プラスチック光ファイバによる生体ラット肝中での発癌関連酵素のin vivo検出

信学技報, OFT98-32 25-30, 1998
環境汚染物質暴露に対する生物指標としての肝シトクロムP450の有用性-北海道沿岸に棲息アザラシを用いた検討-

第126回日本獣医学会, 1998
モクズガニ異物代謝酵素をバイオマーカーとした水圏汚染の環境インパクトのモニタリング

第126回日本獣医学会, 1998
野生エゾヤチネズミ肝ミクロソームにおけるCytochrome P450依存活性の生息地域差

第126回日本獣医学会, 1998

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Professional Memberships

5

Research Projects

2