野口直哉 (Naoya Noguchi) - マイポータル

基本情報

所属: 旧所属東北大学大学院医学系研究科先端再生生命科学（江東微生物研究所）寄附講座助教

学位: 博士(医学)(東北大学)

J-GLOBAL ID: 200901038454914231
researchmap会員ID: 1000247539

研究キーワード

研究分野

経歴

1999年 - 2001年

東北大学
2001年

- 東北大学
1997年 - 1999年

東北大学

学歴

MISC

Thiazolidinediones inhibit REG I alpha gene transcription in gastrointestinal cancer cells

Akiyo Yamauchi, Iwao Takahashi, Shin Takasawa, Koji Nata, Naoya Noguchi, Takayuki Ikeda, Takeo Yoshikawa, Nausheen J. Shervani, Iwao Suzuki, Akira Uruno …

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 379(3) 743-748 2009年2月
FKBP12.6 disruption impairs glucose-induced insulin secretion

Naoya Noguchi, Takeo Yoshikawa, Takayuki Ikeda, Iwao Takahashi, Nausheen Jamal Shervani, Akira Uruno, Akiyo Yamauchi, Koji Nata, Shin Takasawa, Hiroshi Okamoto …

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 371(4) 735-740 2008年7月
CD38 is critical for social behaviour by regulating oxytocin secretion

Duo Jin, Hong-Xiang Liu, Hirokazu Hirai, Takashi Torashima, Taku Nagai, Olga Lopatina, Natalia A. Shnayder, Kiyofumi Yamada, Mami Noda, Toshihiro Seike …

NATURE 446(7131) 41-45 2007年3月
Cyclin D1 activation through ATF-2 in reg-induced pancreatic beta-cell regeneration

S Takasawa, T Ikeda, T Akiyama, K Nata, K Nakagawa, NJ Shervani, N Noguchi, S Murakami-Kawaguchi, A Yamauchi, Takahashi, I …

FEBS LETTERS 580(2) 585-591 2006年1月
Genomic organization, chromosomal localization, and promoter of human gene for FK506-binding protein 12.6

T Nakazawa, S Takasawa, N Noguchi, K Nata, A Tohgo, M Mori, K Nakagawara, T Akiyama, T Ikeda, A Yamauchi …

GENE 360(1) 55-64 2005年10月
Molecular cloning, expression and chromosomal localization of a novel human REG family gene, REG III

K Nata, Y Liu, LQ Xu, T Ikeda, T Akiyama, N Noguchi, S Kawaguchi, A Yamauchi, Takahashi, I, NJ Shervani …

GENE 340(1) 161-170 2004年9月
Autoantibodies to REG, a beta-cell regeneration factor, in diabetic patients.

Eur J Clin Invest 34(11) 752-758 2004年
Autoantibodies to REG, a beta-cell regeneration factor, in diabetic patients.

Eur J Clin Invest 34(11) 752-758 2004年
Production and characterization of Reg knockout mice: reduced proliferation of pancreatic beta-cells in Reg knockout mice.

Diabetes 51 Suppl 3 S478-83 2002年
Production and characterization of Reg knockout mice: reduced proliferation of pancreatic beta-cells in Reg knockout mice.

Diabetes 51 Suppl 3 S478-83 2002年
Altered stoichiometry of FKBP12.6 versus ryanodine receptor as a cause of abnormal Ca2+ leak through ryanodine receptor in heart failure

M Yano, K Ono, T Ohkusa, M Suetsugu, M Kohno, T Hisaoka, S Kobayashi, Y Hisamatsu, T Yamamoto, M Kohno …

CIRCULATION 102(17) 2131-2136 2000年10月
Physiological and pathological significance of the CD38-cyclic ADP-ribose signaling system. (Chem Immunol)

Chem Immunol 75 121-145 2000年
Physiological and pathological significance of the CD38-cyclic ADP-ribose signaling system. (Chem Immunol)

Chem Immunol 75 121-145 2000年
CD38 disruption impairs glucose-induced increases in cyclic ADP-ribose, [Ca2+]i, and insulin secretion.

KATO I, YAMAMOTO Y, FUJIMURA M, NOGUCHI N, TAKASAWA S, OKAMOTO H

J Biol Chem 274(4) 1869-1872 1999年
CD38 disruption impairs glucose-induced increases in cyclic ADP-ribose, [Ca2+]i, and insulin secretion.

J Biol Chem 274(4) 1869-1872 1999年
Cyclic ADP-ribose and inositol 1,4,5-trisphosphate as alternate second messengers for intracellular Ca2+ mobilization in normal and diabetic beta-cells.

TAKASAWA S, NATA K, KUROKI M, TOHGO A, NOGUCHI N, KOBAYASHI S, KATO I, KATADA T, OKAMOTO H

J Biol Chem 273(5) 2497-2500 1998年
Cyclic ADP-ribose and inositol 1,4,5-trisphosphate as alternate second messengers for intracellular Ca2+ mobilization in normal and diabetic beta-cells.

J Biol Chem 273(5) 2497-2500 1998年
Structure, chromosomal localization and expression of mouse genes encoding type III Reg, RegIII alpha, RegIII beta, RegIII gamma

Y Narushima, M Unno, K Nakagawara, M Mori, H Miyashita, Y Suzuki, N Noguchi, S Takasawa, T Kumagai, H Yonekura …

GENE 185(2) 159-168 1997年2月
Synthesis and hydrolysis of cyclic ADP-ribose by human leukocyte antigen CD38: inhibition of hydrolysis by ATP and physiological significance. (Methods Enzymol)

Methods Enzymol 280 306-318 1997年
Cyclic ADP-ribose binds to FK506-binding protein 12.6 to release Ca2+ from islet microsomes.

NOGUCHI N, TAKASAWA S, NATA K, TOHGO A, KATO I, IKEHATA F, YONEKURA H, OKAMOTO H

J Biol Chem 272(6) 3133-3136 1997年

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野口直哉

基本情報

研究キーワード

研究分野

経歴

学歴

MISC

所属学協会

共同研究・競争的資金等の研究課題

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