論文

査読有り
2012年7月

Osteoblast compatibility of materials depends on serum protein absorbability in osteogenesis.

Dental materials journal
  • Kenichi Harimoto
  • ,
  • Yasuhiro Yoshida
  • ,
  • Kumiko Yoshihara
  • ,
  • Noriyuki Nagaoka
  • ,
  • Takuya Matsumoto
  • ,
  • Yoh-ichi Tagawa

31
4
開始ページ
674
終了ページ
80
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.4012/dmj.2012-075
出版者・発行元
JAPANESE SOC DENTAL MATERIALS DEVICES

Titanium has an osseointegrative property, while hydroxyapatite has an osteoconductive property. It remains a matter of controversy among researchers whether hydroxyapatite has higher osteoblast compatibility than titanium. Here, we compared the activities between osteoblasts cultured on titanium and those cultured on hydroxyapatite. An osteoblast-like cell line, MC3T3-E1, was cultured on machined titanium, evaporated titanium, and hydroxyapatite disks to compare the affinity of osteoblasts to each of these materials. The adhesion and proliferation of MC3T3-E1 cells were higher on hydroxyapatite disks than on the other disks. Osteoblast differentiation was not affected by the nature of disks investigated, but calcium was more easily deposited on the hydroxyapatite disks. The amount of absorbed serum proteins detected on hydroxyapatite was greater than that on titanium. In conclusion, our results indicate hydroxyapatite is a more suitable material for osteoblast growth than titanium because of its higher absorption of serum proteins.

リンク情報
DOI
https://doi.org/10.4012/dmj.2012-075
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/22864224
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000309250600024&DestApp=WOS_CPL
ID情報
  • DOI : 10.4012/dmj.2012-075
  • ISSN : 0287-4547
  • eISSN : 1881-1361
  • PubMed ID : 22864224
  • Web of Science ID : WOS:000309250600024

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