2000年
Detection of human α-defensin-1, an antimicrobial peptide, in the fluid of jaw cysts
Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics
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- 巻
- 90
- 号
- 1
- 開始ページ
- 78
- 終了ページ
- 81
- 記述言語
- 英語
- 掲載種別
- DOI
- 10.1067/moe.2000.107055
Objective. The purpose of this study was to isolate and to identify an antimicrobial peptide, human α-defensin-1 (HNP-1) in jaw cyst fluid. Study design. We collected jaw cyst fluid from 22 patients with various jaw cysts and analyzed the peptide components of them by reversed-phase high-performance liquid chromatography (HPLC). HNP-1 in the jaw cyst fluid was identified by the amino acid sequence and the molecular weight. The concentration of HNP-1 in the fluid of various jaw cysts was quantified by HPLC. Results. HNP-1 in the jaw cyst fluid was isolated, purified, and identified. The concentrations of HNP-1 in the jaw cyst fluid ranged from 27.0 to 3725.4 μg/mL. Conclusion. HNP-1 was detected in the fluid of various types of jaw cysts.
- ID情報
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- DOI : 10.1067/moe.2000.107055
- ISSN : 1079-2104
- PubMed ID : 10884640
- SCOPUS ID : 0034222453