Yukako Saito

Profile Information

Affiliation: Faculty of Pharmaceutical Sciences, Department of Pharmaceutical Science, Pharmaceutical Chemistry, Tohoku Medical and Pharmaceutical University

Degree: 博士（薬学）(東北薬科大学)

J-GLOBAL ID: 200901098161451051
researchmap Member ID: 1000250606

Research Interests

Research Areas

Life sciences / Pharmaceuticals - chemistry and drug development /

Research History

Education

Papers

Palladium-Catalyzed Three-Component Coupling of Ynamides

Hideaki Wakamatsu, Ayano Takahashi, Ayaka Ishii, Youhei Kikuchi, Madoka Sasaki, Yukako Saito, Yoshihiro Natori, Yuichi Yoshimura

Organic Letters, 22(14) 5299-5303, Jul 17, 2020
Glycosylation reactions mediated by hypervalent iodine: Application to the synthesis of nucleosides and carbohydrates

Yuichi Yoshimura, Hideaki Wakamatsu, Yoshihiro Natori, Yukako Saito, Noriaki Minakawa

Beilstein Journal of Organic Chemistry, 14 1595-1618, Jun 28, 2018 Peer-reviewed
Synthesis of 4′-thionucleosides as antitumor and antiviral agents

Yuichi Yoshimura, Yukako Saito, Yoshihiro Natori, Hideaki Wakamatsu

Chemical and Pharmaceutical Bulletin, 66(2) 139-146, 2018 Peer-reviewed
Practical Synthesis of 4'-Thioribonucleosides from L-Arabinose via Novel Reductive Ring-Contraction Reaction and Pummerer-Type Thioglycosylation

Hideaki Wakamatsu, Kozue Nitta, Nozomi Shoji, Yoshihiro Natori, Yukako Saito, Yuichi Yoshimura

Current protocols in nucleic acid chemistry, 71 1.43.1-1.43.12, Dec 24, 2017 Peer-reviewed
Synthesis of a dihydropyranonucleoside using an oxidative glycosylation reaction mediated by hypervalent iodine

Hiroya Kan-No, Yukako Saito, Shun Omoto, Sakie Minato, Hideaki Wakamatsu, Yoshihiro Natori, Tomozumi Imamichi, Hiroki Takahata, Yuichi Yoshimura

Synthesis (Germany), 46(7) 879-886, Apr, 2014 Peer-reviewed
Asymmetric synthesis of 2,5-disubstituted 3-hydroxypyrrolidines based on stereodivergent intramolecular iridium-catalyzed allylic aminations

Yoshihiro Natori, Shunsuke Kikuchi, Takahiro Kondo, Yukako Saito, Yuichi Yoshimura, Hiroki Takahata

Organic and Biomolecular Chemistry, 12(12) 1983-1994, Mar 28, 2014 Peer-reviewed
A Facile Synthesis of Fully Protected meso-Diaminopimelic Acid (DAP) and Its Application to the Preparation of Lipophilic N-Acyl iE-DAP

Yukako Saito, Yuichi Yoshimura, Hideaki Wakamatsu, Hiroki Takahata

MOLECULES, 18(1) 1162-1173, Jan, 2013 Peer-reviewed
A new route to N ¹-substituted uracil derivatives using hypervalent iodine

Yuichi Yoshimura, Hiroya Kan-No, Y. B. Kiran, Yoshihiro Natori, Yukako Saito, Hiroki Takahata

Synthesis, 44(8) 1163-1170, 2012 Peer-reviewed
Synthesis of 5-thiodidehydropyranylcytosine derivatives as potential anti-HIV agents

Yuichi Yoshimura, Yoshiko Yamazaki, Yukako Saito, Yoshihiro Natori, Tomozumi Imamichi, Hiroki Takahata

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 21(11) 3313-3316, Jun, 2011 Peer-reviewed
Chemoselective O-tert-butoxycarbonylation of phenols using 6,7-dimethoxyisoquinoline as a novel organocatalyst

Yukako Saito, Yuichi Yoshimura, Hiroki Takahata

TETRAHEDRON LETTERS, 51(52) 6915-6917, Dec, 2010 Peer-reviewed
Synthesis of 1-(5,6-dihydro-2H-thiopyran-2-yl)uracil by a Pummerer-type thioglycosylation reaction: the regioselectivity of allylic substitution

Yuichi Yoshimura, Yoshiko Yamazaki, Yukako Saito, Hiroki Takahata

TETRAHEDRON, 65(45) 9091-9102, Nov, 2009 Peer-reviewed
CATALYTIC ASYMMETRIC SYNTHESIS OF BOTH ENANTIOMERS OF PYRROLIZIDINES 223H ', 239K ', 265H ', AND 267H ' FOUND IN MADAGASCAN FROGS (MANTELLA) AND THEIR AFFINITIES FOR NICOTINIC ACETYLCHOLINE RECEPTOR

Yukako Saito, Seiki Takahashi, Nehad Azer, Amira T. Eldefrawi, Mohyee E. Eldefrawi, Hiroki Takahata

HETEROCYCLES, 79 1043-1060, Apr, 2009 Peer-reviewed
Carboxamidation of carboxylic acids with 1-tert-butoxy-2-tert-butoxycarbonyl-1,2-dihydroisoquinoline (BBDI) without bases

Yukako Saito, Hidekazu Ouchi, Hiroki Takahata

TETRAHEDRON, 64(49) 11129-11135, Dec, 2008 Peer-reviewed
P-42 New Synthesis of meso-Diaminopimelic Acids and Its Application to the Biologically Active Peptides(Poster Presentation)

Saito Yukako, Watanabe Tomokazu, Sato Yumi, Imahori Tatsushi, Yoshimura Yuichi, Takahata Hiroki

Symposium on the Chemistry of Natural Products, symposium papers, (50) 665-670, Sep 1, 2008
Synthesis of both enantiomers of hydroxypipecolic acid derivatives equivalent to 5-azapyranuronic acids and evaluation of their inhibitory activities against glycosidases

Yuichi Yoshimura, Chiaki Ohara, Tatsushi Imahori, Yukako Saito, Atsushi Kato, Saori Miyauchi, Isao Adachi, Hiroki Takahata

BIOORGANIC & MEDICINAL CHEMISTRY, 16(17) 8273-8286, Sep, 2008 Peer-reviewed
P-187 New Synthesis of Orthogonally Protected meso-Diaminopimelic Acid (meso-DAP) and FK565

Watanabe Tomokazu, Saito Yukako, Yoshimura Yuichi, Takahata Hiroki

International Symposium on the Chemistry of Natural Products, 2006 "P-187", Jul 23, 2006

Misc.

Synthesis of 4’-Substituted Thymidines by the Selective Transformation of Hydroxymethyl Group

遠藤柚季乃, 若松秀章, 伊藤恭平, 名取良浩, 斎藤有香子, 吉村祐一

日本薬学会年会要旨集(Web), 141st, 2021
Development of a method for the synthesis of nitrogen-containing heterocyclic compounds using trivalent hypervalent iodine reagents and (PhSe)₂

鈴木郁, 名取良浩, 萬浩太, 若松秀章, 斎藤有香子, 吉村祐一

日本薬学会年会要旨集(Web), 141st, 2021
Palladium-Catalyzed Three-Component Coupling of Ynamides

若松秀章, 高橋彩乃, 石井彩香, 菊地洋平, 佐々木まどか, 斎藤有香子, 名取良浩, 吉村祐一

日本薬学会年会要旨集(Web), 141st, 2021
Synthesis of nitrogen heterocycles by intermolecular reaction using hypervalent iodine and diphenyl diselenide

鈴木郁, 名取良浩, 萬浩太, 若松秀章, 斎藤有香子, 吉村祐一

日本薬学会年会要旨集(CD-ROM), 140th, 2020
Synthesis of the long-chain fatty acid as analogue of GM3 ceramide

名取良浩, 若松秀章, 伊藤瑛將, 袰地陽太, 金野美里, 斎藤有香子, 井ノ口仁一, 吉村祐一

日本薬学会年会要旨集(CD-ROM), 140th, 2020
Kinetic resolution of 4’-substituted nucleoside derivatives

遠藤柚季乃, 若松秀章, 伊藤恭平, 斎藤有香子, 名取良浩, 吉村祐一

日本薬学会年会要旨集(CD-ROM), 140th, 2020
超原子価ヨウ素とジフェニルジセレニドを用いた含窒素複素環化合物の合成法の開発

鈴木郁, 名取良浩, 萬浩太, 若松秀章, 斎藤有香子, 吉村祐一

創薬懇話会講演要旨集, 2019, 2019
A straightforward stereoselective synthesis of meso-, (S,S)- and (R,R)-2,6-diaminopimelic acids from cis-1,4-diacetoxycyclohept-2-ene

Yukako Saito, Takurni Shinkai, Yuichi Yoshimura, Hiroki Takahata

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 17(21) 5894-5896, Nov, 2007
An asymmetric synthesis of all stereoisomers of piclavines AI-4 using an iterative asymmetric dihydroxylation

Yukako Saito, Naoki Okamoto, Hiroki Takahata

BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY, 3 37, Oct, 2007
A novel tert-butoxycarbonylation reagent: 1-tert-butoxy-2-tertbutoxycarbonyl-1,2-dihydroisoquinoline (BBDI)

Yukako Saito, Hidekazu Ouchi, Hiroki Takahata

TETRAHEDRON, 62(50) 11599-11607, Dec, 2006
A novel 1-tert-butoxy-2-tert-butoxycarbonyl-1,2dihydroisoquinoline (BBDI)-catalyzed esterification of N-protected amino acids with nearly equimolar amounts of alcohols in the presence of BoC(2)O

Y Saito, T Watanabe, H Takahata

TETRAHEDRON LETTERS, 47(18) 3099-3102, May, 2006
A new route to trans-2,6-disubstituted piperidine-related alkaloids using a novel C-2-symmetric 2,6-diallylpiperidine carboxylic acid methyl ester

H Takahata, Y Saito, M Ichinose

ORGANIC & BIOMOLECULAR CHEMISTRY, 4(8) 1587-1595, 2006
Simple and mild esterification of N-protected amino acids with nearly equimolar amounts of alcohols using 1-tert-butoxy-2-tert-butoxycarbonyl-1,2-dihydroisoquinoline

Y Saito, T Yamaki, F Kohashi, T Watanabe, H Ouchi, H Takahata

TETRAHEDRON LETTERS, 46(8) 1277-1279, Feb, 2005
Simple and mild esterification of N-protected amino acids with nearly equimolar amounts of alcohols using 1-tert-butoxy-2-tert-butoxycarbonyl-1,2-dihydroisoquinoline

Y Saito, T Yamaki, F Kohashi, T Watanabe, H Ouchi, H Takahata

TETRAHEDRON LETTERS, 46(8) 1277-1279, Feb, 2005
1-tert-butoxy-2-tert-butoxycarbonyl-1,2-dihydroisoquinoline: A novel and chemoselective tert-butoxycarbonylation reagent

H Ouchi, Y Saito, Y Yamamoto, H Takahata

ORGANIC LETTERS, 4(4) 585-587, Feb, 2002
1-tert-Butoxy-2-tert-butoxycarbonyl-1,2-dihydroisoquinoline: A Novel and Chemose- lective tert-Butoxycarbonylation Reagent

Org. Lett., 4(4), 585-587, 2002
Di-tert-butyl DicarbonateとBenzodiazine類との反応とその成績体の合成的利用

東北薬科大学研究年報, 45,111, 1998
Reactions of Di-tert-butyl Dicarbonate with Benzodiazines and Synthetic Applications of the Products

Annual Report to Tohoku College of Pharmacy, 45,111-116, 1998

Professional Memberships

Research Projects

Preparation and evaluation of diaminopimelic acid derivatives as multifunctional pharmaceutical materials

Grants-in-Aid for Scientific Research, Grant-in-Aid for Young Scientists (B), Japan Society for the Promotion of Science, 2008 - 2010

SAITO Yukako
Production of novel isoquinoline-containing functional reagents and new developmet

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, 2003 - 2005

TAKAHATA Hiroki, SAITO Yukako
複素環化合物を利用した機能性試薬の開発

2001
Development of functional reagent using heterocyclic compound

2001

Profile Information

Research Interests

Research Areas

Research History

Education

Papers

Misc.

Professional Memberships

Research Projects

Menu

Coauthors