玄 学南

J-GLOBALへ         更新日: 18/12/26 20:28
 
アバター
研究者氏名
玄 学南
 
ゲン ガクナン
URL
http://www.obihiro.ac.jp/~protozoa/
所属
帯広畜産大学
部署
原虫病研究センター
職名
教授
学位
農学博士

研究分野

 
 

学歴

 
1988年4月
 - 
1991年3月
東京大学 大学院農学系研究科博士課程 獣医畜産学専攻
 

委員歴

 
 
   
 
日本獣医学会  評議員
 
 
   
 
日本寄生虫学会  評議員
 
 
   
 
日本獣医寄生虫学会  評議員
 

論文

 
Molecular survey and characterization of Theileria annulata and Ehrlichia ruminantium in cattle from Northwest China
Guo H, Yin C, Galon EM, Du J, Gao Y, Adjou Moumouni PF, Liu M, Efstratiou A, Lee SH, Li J, Ringo AE, Wang G, Li Y, Tumwebaze MA, Xuan X.
Parasitol Int   67(6) 679-683   2018年12月   [査読有り]
Molecular detection and characterization of tick-borne protozoan and rickettsial pathogens isolated from cattle on Pemba Island, Tanzania
Ringo AE, Adjou Moumouni PF, Lee SH, Liu M, Khamis YH, Gao Y, Guo H, Zheng W, Efstratiou A, Galon EM, Li J, Tiwananthagorn S, Inoue N, Suzuki H, Thekisoe O, Xuan X
Ticks Tick Borne Dis   9(6) 1437-1445   2018年9月   [査読有り]
Serological and molecular detection of Theileria equi and Babesia caballi in Philippine horses
Ybañez AP, Ybañez RHD, Talle MG, Arreglo RMT, Geens MJC, Villas JGI 3rd, Villar SR, Laruga CL, Cao S, Moumouni FPA, Liu M, Igarashi I, Xuan X
Ticks Tick Borne Dis   9(5) 1125-1128   2018年7月   [査読有り]
Evaluation of the protective effect of a prime-boost strategy with plasmid DNA followed by recombinant adenovirus expressing BmAMA1 as vaccines against Babesia microti infection in hamster
Wang G, Yu L, Efstratiou A, Moumouni PFA, Liu M, Guo H, Gao Y, Cao S, Zhou M, Li J, Ringo AE, Xuan X
Acta Parasitol   63(2) 368-374   2018年6月   [査読有り]
Molecular analysis of tick-borne protozoan and rickettsial pathogens in small ruminants from two South African provinces
Ringo AE, Adjou Moumouni PF, Taioe M, Jirapattharasate C, Liu M, Wang G, Gao Y, Guo H, Lee SH, Zheng W, Efstratiou A, Li J, Inoue N, Suzuki H, Thekisoe O, Xuan X
Parasitol Int   67(2) 144-149   2018年4月   [査読有り]
Establishment of a stable transfection system for genetic manipulation of Babesia gibsoni
Liu M, Adjou Moumouni PF, Asada M, Hakimi H, Masatani T, Vudriko P, Lee SH, Kawazu SI, Yamagishi J, Xuan X
Parasit Vectors   11(1) 260   2018年4月   [査読有り]
Prevalence, risk factors, and genetic diversity of veterinary important tick-borne pathogens in cattle from Rhipicephalus microplus-invaded and non-invaded areas of Benin
Adjou Moumouni PF, Aplogan GL, Katahira H, Gao Y, Guo H, Efstratiou A, Jirapattharasate C, Wang G, Liu M, Ringo AE, Umemiya-Shirafuji R, Suzuki H, Xuan X
Ticks Tick Borne Dis   9(3) 450-464   2018年3月   [査読有り]
Detection and molecular characterization of tick-borne pathogens infecting sheep and goats in Blue Nile and West Kordofan states in Sudan
Lee SH, Mossaad E, Ibrahim AM, Ismail AA, Adjou Moumouni PF, Liu M, Ringo AE, Gao Y, Guo H, Li J, Efstratiou A, Musinguzi P, Angara TEE, Suganuma K, Inoue N, Xuan X
Ticks Tick Borne Dis   9(3) 598-604   2018年3月   [査読有り]
Haemoparasitic agents associated with ovine babesiosis: A possible negative interaction between Babesia ovis and Theileria ovis
Sevinc F, Zhou M, Cao S, Ceylan O, Aydin MF, Sevinc M, Xuan X
Vet Parasitol   252 143-147   2018年3月   [査読有り]
Identification and characterization of interchangeable cross-species functional promoters between Babesia gibsoni and Babesia bovis
Liu M, Adjou Moumouni PF, Cao S, Asada M, Wang G, Gao Y, Guo H, Li J, Vudriko P, Efstratiou A, Ringo AE, Lee SH, Hakimi H, Masatani T, Sunaga F, Kawazu SI, Yamagishi J, Jia L, Inoue N, Xuan X
Ticks Tick Borne Dis   9(2) 330-333   2018年2月   [査読有り]
Detection of Ehrlichia, Anaplasma, and Babesia spp. in dogs of Cebu, Philippines
Ybañez RHD, Ybañez AP, Arnado LLA, Belarmino LMP, Malingin KGF, Cabilete PBC, Amores ZRO, Talle MG, Liu M, Xuan X
Vet World   11(1) 14-19   2018年1月   [査読有り]
Human babesiosis: Indication of a molecular mimicry between thrombospondin domains from a novel Babesia microti BmP53 protein and host platelets molecules
Mousa AA, Roche DB, Terkawi MA, Kameyama K, Kamyingkird K, Vudriko P, Salama A, Cao S, Orabi S, Khalifa H, Ahmed M, Attia M, Elkirdasy A, Nishikawa Y, Xuan X, Cornillot E
PLoS One   12(10) e0185372   2017年10月   [査読有り]
Transient transfection of intraerythrocytic Babesia gibsoni using elongation factor-1 alpha promoter
Liu M, Asada M, Cao S, Adjou Moumouni PF, Vudriko P, Efstratiou A, Hakimi H, Masatani T, Sunaga F, Kawazu SI, Yamagishi J, Xuan X
Mol Biochem Parasitol   216 56-59   2017年9月   [査読有り]
Effects of dihydroorotate dehydrogenase (DHODH) inhibitors on the growth of Theileria equi and Babesia caballi in vitro
Kamyingkird K, Cao S, Tuvshintulga B, Salama A, Mousa AA, Efstratiou A, Nishikawa Y, Yokoyama N, Igarashi I, Xuan X
Exp Parasitol   176 59-65   2017年5月   [査読有り]
First report on Babesia vogeli infection in dogs in the Philippines
Ybañez AP, Ybañez RH, Talle MG, Liu M, Moumouni PF, Xuan X
Parasitol Int   66(1) 813-815   2017年2月   [査読有り]
First molecular detection of tick-borne pathogens in dogs from Jiangxi, China
Zheng W, Liu M, Moumouni PF, Liu X, Efstratiou A, Liu Z, Liu Y, Tao H, Guo H, Wang G, Gao Y, Li Z, Ringo AE, Jirapattharasate C, Chen H, Xuan X
J Vet Med Sci   79(2) 248-254   2017年2月   [査読有り]
Molecular detection and genetic characterization of Babesia, Theileria and Anaplasma amongst apparently healthy sheep and goats in the central region of Turkey
Zhou M, Cao S, Sevinc F, Sevinc M, Ceylan O, Ekici S, Jirapattharasate C, Moumouni PF, Liu M, Wang G, Iguchi A, Vudriko P, Suzuki H, Xuan X
Ticks Tick Borne Dis   8(2) 246-252   2017年2月   [査読有り]
Molecular detection and genetic diversity of bovine Babesia spp., Theileria orientalis, and Anaplasma marginale in beef cattle in Thailand
Jirapattharasate C, Adjou Moumouni PF, Cao S, Iguchi A, Liu M, Wang G, Zhou M, Vudriko P, Efstratiou A, Changbunjong T, Sungpradit S, Ratanakorn P, Moonarmart W, Sedwisai P, Weluwanarak T, Wongsawang W, Suzuki H, Xuan X
Parasitol Res   116(2) 751-762   2017年2月   [査読有り]
Enzyme-linked immunosorbent assays using recombinant TgSAG2 and NcSAG1 to detect Toxoplasma gondii and Neospora caninum-specific antibodies in domestic animals in Turkey
Zhou M, Cao S, Sevinc F, Sevinc M, Ceylan O, Liu M, Wang G, Moumouni PF, Jirapattharasate C, Suzuki H, Nishikawa Y, Xuan X
J Vet Med Sci   78(12) 1877-1881   2017年1月   [査読有り]
Expression of truncated Babesia microti apical membrane protein 1 and rhoptry neck protein 2 and evaluation of their protective efficacy
Wang G, Efstratiou A, Adjou Moumouni PF, Liu M, Jirapattharasate C, Guo H, Gao Y, Cao S, Mo Zhou, Suzuki H, Igarashi I, Xuan X
Exp Parasitol   172 5-11   2017年1月   [査読有り]
Primary Babesia rodhaini infection followed by recovery confers protective immunity against B. rodhaini reinfection and Babesia microti challenge infection in mice
Wang G, Efstratiou A, Adjou Moumouni PF, Liu M, Jirapattharasate C, Guo H, Gao Y, Cao S, Zhou M, Suzuki H, Igarashi I, Xuan X
Exp Parasitol   169 6-12   2016年10月   [査読有り]
Identification and functional analysis of a novel mitochondria-localized 2-Cys peroxiredoxin, BbTPx-2, from Babesia bovis
Masatani T, Asada M, Hakimi H, Hayashi K, Yamagishi J, Kawazu S, Xuan X
Parasitol Res   115(8) 3139-3145   2016年8月   [査読有り]
Molecular survey of canine vector-borne diseases in stray dogs in Thailand
Liu M, Ruttayaporn N, Saechan V, Jirapattharasate C, Vudriko P, Moumouni PF, Cao S, Inpankaew T, Ybañez AP, Suzuki H, Xuan X
Parasitol Int   65(4) 357-361   2016年8月   [査読有り]
Molecular detection of spotted fever group rickettsiae in Amblyomma variegatum ticks from Benin
Adjou Moumouni PF, Terkawi MA, Jirapattharasate C, Cao S, Liu M, Nakao R, Umemiya-Shirafuji R, Yokoyama N, Sugimoto C, Fujisaki K, Suzuki H, Xuan X
Ticks Tick Borne Dis   7(5) 828-833   2016年7月   [査読有り]
Babesia gibsoni internal transcribed spacer 1 region is highly conserved amongst isolates from dogs across Japan
Liu M, Cao S, Vudriko P, Suzuki H, Soma T, Xuan X
J Vet Med Sci   78(5) 863-865   2016年6月   [査読有り]
Molecular identification and antigenic characterization of a merozoite surface antigen and a secreted antigen of Babesia canis (BcMSA1 and BcSA1)
Zhou M, Cao S, Luo Y, Liu M, Wang G, Moumouni PF, Jirapattharasate C, Iguchi A, Vudriko P, Terkawi MA, Löwenstein M, Kern A, Nishikawa Y, Suzuki H, Igarashi I, Xuan X
Parasit Vectors   9 257   2016年5月   [査読有り]
The epidemiological survey for atovaquone resistant related gene of Babesia gibsoni in Japan
Iguchi A, Soma T, Suzuki H, Xuan X
J Vet Med Sci   78(3) 489-491   2016年3月   [査読有り]
Genetic variations of four immunodominant antigens of Babesia gibsoni isolated from dogs in southwest Japan
Liu M, Cao S, Zhou M, Wang G, Jirapattharasate C, Moumouni PF, Iguchi A, Vudriko P, Suzuki H, Soma T, Xuan X
Ticks Tick Borne Dis   7(2) 298-305   2016年3月   [査読有り]
Molecular epidemiology of bovine Babesia spp. and Theileria orientalis parasites in beef cattle from northern and northeastern Thailand
Jirapattharasate C, Adjou Moumouni PF, Cao S, Iguchi A, Liu M, Wang G, Zhou M, Vudriko P, Changbunjong T, Sungpradit S, Ratanakorn P, Moonarmart W, Sedwisai P, Weluwanarak T, Wongsawang W, Suzuki H, Xuan X
Parasitol Int   65(1) 62-69   2016年2月   [査読有り]
Molecular detection and genetic identification of Babesia bigemina, Theileria annulata, Theileria orientalis and Anaplasma marginale in Turkey
Zhou M, Cao S, Sevinc F, Sevinc M, Ceylan O, Moumouni PFA, Jirapattharasate C, Liu M, Wang G, Iguchi A, Vudriko P, Suzuki H, Xuan X
Ticks Tick Borne Dis   7(1) 126-134   2016年2月   [査読有り]
Characterization of Toxoplasma gondii glyoxalase 1 and evaluation of inhibitory effects of curcumin on the enzyme and parasite cultures
Goo YK, Yamagishi J, Ueno A, Terkawi MA, Aboge GO, Kwak D, Hong Y, Chung DI, Igarashi M, Nishikawa Y, Xuan X
Parasit Vectors   8 654   2015年12月   [査読有り]
A new immunoreactive recombinant protein designated as rBoSA2 from Babesia ovis: Its molecular characterization, subcellular localization and antibody recognition by infected sheep
Sevinc F, Cao S, Zhou M, Sevinc M, Ceylan O, Xuan X
Vet Parasitol   214(1-2) 213-218   2015年11月   [査読有り]
Molecular Characterization of Babesia bovis M17 Leucine Aminopeptidase and Inhibition of Babesia Growth by Bestatin
Aboge GO, Cao S, Terkawi MA, Masatani T, Goo Y, AbouLaila M, Nishikawa Y, Igarashi I, Suzuki H, Xuan X
J Parasitol   101(5) 536-541   2015年10月   [査読有り]
Molecular detection and characterization of Babesia bovis, Babesia bigemina, Theileria species and Anaplasma marginale isolated from cattle in Kenya
Adjou Moumouni PF, Aboge GO, Terkawi MA, Masatani T, Cao S, Kamyingkird K, Jirapattharasate C, Zhou M, Wang G, Liu M, Iguchi A, Vudriko P, Ybanez AP, Inokuma H, Shirafuji-Umemiya R, Suzuki H, Xuan X
Parasit Vectors   8 496   2015年9月   [査読有り]
Identification and expression of Babesia ovis secreted antigen 1 and evaluation of its diagnostic potential in an enzyme-linked immunosorbent assay
Sevinc F, Cao S, Xuan X, Sevinc M, Ceylan O
J Clin Microbiol   53(5) 1531-1536   2015年5月   [査読有り]
Macrophages are the determinant of resistance to and outcome of nonlethal Babesia microti infection in mice
Terkawi MA, Cao S, Herbas MS, Nishimura M, Li Y, Moumouni PF, Pyarokhil AH, Kondoh D, Kitamura N, Nishikawa Y, Kato K, Yokoyama N, Zhou J, Suzuki H, Igarashi I, Xuan X
Infect Immun   83(1) 8-16   2015年1月   [査読有り]
DB-AT: a 2015 update to the Full-parasites database brings a multitude of new transcriptomic data for apicomplexan parasites
Jąkalski M, Wakaguri H, Kischka TG, Nishikawa Y, Kawazu S, Matsubayashi M, Kawahara F, Tsuji N, Cao S, Sunaga F, Xuan X, Okubo K, Igarashi I, Tuda J, Mongan AE, Eshita Y, Maeda R, Makałowski W, Suzuki Y, Yamagishi J
Nucleic Acids Res   43 631-636   2015年1月   [査読有り]
Molecular and seroepidemiological survey of Babesia bovis and Babesia bigemina infections in cattle and water buffaloes in the central region of Vietnam
Li Y, Luo Y, Cao S, Terkawi MA, Lan DT, Long PT, Yu L, Zhou M, Gong H, Zhang H, Zhou J, Yokoyama N, Suzuki H, Xuan X
Trop Biomed   31(3) 406-413   2014年9月   [査読有り]
Mycophenolic acid, mycophenolate mofetil, mizoribine, ribavirin, and 7-nitroindole inhibit propagation of Babesia parasites by targeting inosine 5'-monophosphate dehydrogenase
Cao S, Aboge GO, Terkawi MA, Zhou M, Kamyingkird K, Moumouni PF, Masatani T, Igarashi I, Nishikawa Y, Suzuki H, Xuan X
J Parasitol   100(4) 522-526   2014年8月   [査読有り]
The Babesia bovis gene and promoter model: an update from full-length EST analysis
Yamagishi J, Wakaguri H, Yokoyama N, Yamashita R, Suzuki Y, Xuan X, Igarashi I
BMC Genomics   15 678   2014年8月   [査読有り]
New Molecules in Babesia gibsoni and their application for diagnosis, vaccine development, and drug discovery
Goo YK, Xuan X
Korean J Parasitol   52(4) 345-353   2014年8月   [査読有り]
Molecular and Kinetic Characterization of Babesia microti Gray Strain Lactate Dehydrogenase as a Potential Drug Target
Vudriko P, Masatani T, Cao S, Terkawi MA, Kamyingkird K, Mousa AA, Adjou Moumouni PF, Nishikawa Y, Xuan X
Drug Target Insights   8 31-38   2014年7月   [査読有り]
Seroprevalence of Neospora caninum infection in dairy cows in Northern provinces, Thailand
Inpankaew T, Jittapalapong S, Mitchell TJ, Sununta C, Igarashi I, Xuan X
Acta Parasitol   59(2) 305-309   2014年6月   [査読有り]
Babesia bovis dihydroorotate dehydrogenase (BboDHODH) is a novel molecular target of drug for bovine babesiosis
Kamyingkird K, Cao S, Masatani T, Moumouni PF, Vudriko P, Mousa AA, Terkawi MA, Nishikawa Y, Igarashi I, Xuan X
J Vet Med Sci   76(3) 323-330   2014年3月   [査読有り]
Cloning and characterization of a 2-Cys peroxiredoxin from Babesia gibsoni
Masatani T, Asada M, Ichikawa-Seki M, Usui M, Terkawi MA, Hayashi K, Kawazu S, Xuan X
J Vet Med Sci   76(1) 139-143   2014年1月   [査読有り]
Prime-boost vaccination with plasmid DNA followed by recombinant vaccinia virus expressing BgGARP induced a partial protective immunity to inhibit Babesia gibsoni proliferation in dogs
Cao S, Mousa AA, Aboge GO, Kamyingkird K, Zhou M, Moumouni PF, Terkawi MA, Masatani T, Nishikawa Y, Suzuki H, Fukumoto S, Xuan X
Acta Parasitol   58(4) 619-623   2013年12月   [査読有り]
Actin polymerization mediated by Babesia gibsoni aldolase is required for parasite invasion
Goo YK, Ueno A, Terkawi MA, Aboge GO, Junya Y, Igarashi M, Kim JY, Hong YC, Chung DI, Nishikawa Y, Xuan X
Exp Parasitol   135(1) 42-49   2013年9月   [査読有り]
Molecular detection of Theileria species in sheep from northern China
Cao S, Zhang S, Jia L, Xue S, Yu L, Kamyingkird K, Moumouni PF, Moussa AA, Zhou M, Zhang Y, Terkawi MA, Masatani T, Nishikawa Y, Xuan X
J Vet Med Sci   75(9) 1227-1230   2013年8月   [査読有り]
TgGRA23, a novel Toxoplasma gondii dense granule protein associated with the parasitophorous vacuole membrane and intravacuolar network
Masatani T, Matsuo T, Tanaka T, Terkawi MA, Lee EG, Goo YK, Aboge GO, Yamagishi J, Hayashi K, Kameyama K, Cao S, Nishikawa Y, Xuan X
Parasitol Int   62(4) 372-379   2013年8月   [査読有り]
Epidemiological survey of Babesia bovis and Babesia bigemina infections of cattle in Philippines
Yu L, Terkawi MA, Cruz-Flores MJ, Claveria FG, Aboge GO, Yamagishi J, Goo YK, Cao S, Masatani T, Nishikawa Y, Xuan X
J Vet Med Sci   75(7) 995-998   2013年7月   [査読有り]

競争的資金等の研究課題

 
トルコにおける家畜バベシア症に対するゲノム疫学調査と実践的制御戦略の確立
日本学術振興会: 国際共同研究加速基金(国際共同研究強化(B))
研究期間: 2018年10月 - 2022年3月    代表者: 玄 学南
マダニ体内におけるバベシア原虫発育の分子基盤の解明と伝播阻止ワクチンの開発
日本学術振興会: 基盤研究(B)
研究期間: 2018年4月 - 2022年3月    代表者: 玄 学南
ネズミバベシア原虫:マダニ体内ステージ発育の分子基盤の解明と新規制御法の開発
日本学術振興会: 特別研究員奨励費
研究期間: 2018年11月 - 2020年10月    代表者: 玄 学南
マダニ体内におけるバベシア原虫発育の分子基盤の解明と伝播阻止ワクチンの開発
日本学術振興会: 特別研究員奨励費
研究期間: 2018年5月 - 2020年3月    代表者: 玄 学南
マダニ媒介原虫感染症の制圧に向けた国際共同研究拠点の構築
日本学術振興会: 拠点形成事業
研究期間: 2017年4月 - 2020年3月    代表者: 玄 学南
東南アジアにおける牛マダニ媒介原虫病の疫学調査と制御対策へのゲノム学的アプローチ
日本学術振興会: 特別研究員奨励費
研究期間: 2017年4月 - 2019年3月    代表者: 玄 学南