2010年8月
The evolution of mammalian chemokine genes
CYTOKINE & GROWTH FACTOR REVIEWS
- ,
- ,
- 巻
- 21
- 号
- 4
- 開始ページ
- 253
- 終了ページ
- 262
- 記述言語
- 英語
- 掲載種別
- DOI
- 10.1016/j.cytogfr.2010.03.004
- 出版者・発行元
- ELSEVIER SCI LTD
Chemokines play an important role in orchestrating cell recruitment and localization in both physiological and pathological conditions. More than 44 ligands have been identified in the human genome. A significantly different set of chemokines, however, is found in the mouse genome, suggesting a rapid evolution of the chemokine system in mammalian genomes. Thus, there are lineage and even individual-specific differences in chemokine genes in mammals. Differences in the expression and function between even recently duplicated genes are also evident. In this review, we discuss how evolutionary events such as gene duplication and gene conversion have shaped the diverse arrays of chemokines in mammalian genomes. (C) 2010 Elsevier Ltd. All rights reserved.
- リンク情報
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- DOI
- https://doi.org/10.1016/j.cytogfr.2010.03.004
- PubMed
- https://www.ncbi.nlm.nih.gov/pubmed/20434943
- Web of Science
- https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000283000900004&DestApp=WOS_CPL
- URL
- https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=77956406542&origin=inward
- ID情報
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- DOI : 10.1016/j.cytogfr.2010.03.004
- ISSN : 1359-6101
- PubMed ID : 20434943
- SCOPUS ID : 77956406542
- Web of Science ID : WOS:000283000900004