石崎高志 (Takashi Ishizaki) - マイポータル

基本情報

所属: 旧所属熊本大学大学院医学薬学研究部総合医薬科学部門教授,その他

学位: 博士(医学)

J-GLOBAL ID: 200901030238892320
researchmap会員ID: 1000253807

研究キーワード

研究分野

ライフサイエンス / 薬理学 /

学歴

- 1969年

北海道大学, 医学系研究科
- 1969年

北海道大学

委員歴

受賞

1992年

Drug innovation science research fellowship from Human Science Foundation
1990年

Research fellowship from the Ministry of Human Health and Welfare,Japan.
1988年

Research fellowship from the Ministry of Education,Science and Culture
1988年

Research fellowship from Nakatomi Health Science Foundation,Japan
1985年

Special research fellowship for sick children from the Ministry of Human Health and Welfare,Japan

MISC

Human buprenorphine N-dealkylation is catalyzed by cytochrome P450 3A4

K Kobayashi, T Yamamoto, K Chiba, M Tani, N Shimada, T Ishizaki, Y Kuroiwa

DRUG METABOLISM AND DISPOSITION 26(8) 818-821 1998年8月
Inhibitory effects of antiarrhythmic drugs on phenacetin O-deethylation catalysed by human CYP1A2

K Kobayashi, M Nakajima, K Chiba, T Yamamoto, M Tani, T Ishizaki, Y Kuroiwa

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY 45(4) 361-368 1998年4月
The in vitro hepatic metabolism of quinine in mice, rats and dogs: Comparison with human liver microsomes

XJ Zhao, T Ishizaki

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 283(3) 1168-1176 1997年12月
Metabolic disposition of pantoprazole, a proton pump inhibitor, in relation to S-mephenytoin 4 '-hydroxylation phenotype and genotype

M Tanaka, T Ohkubo, K Otani, A Suzuki, S Kaneko, K Sugawara, Y Ryokawa, H Hakusui, S Yamamori, T Ishizaki

CLINICAL PHARMACOLOGY & THERAPEUTICS 62(6) 619-628 1997年12月
Metabolic interactions of selected antimalarial and non-antimalarial drugs with the major pathway (3-hydroxylation) of quinine in human liver microsomes

XJ Zhao, T Ishizaki

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY 44(5) 505-511 1997年11月
Genetic analysis of CYP2C9 polymorphism in a Japanese population

K Nasu, T Kubota, T Ishizaki

PHARMACOGENETICS 7(5) 405-409 1997年10月
Prediction of in vivo hepatic metabolic clearance of YM796 from in vitro data by use of human liver microsomes and recombinant P-450 isozymes

T Iwatsubo, H Suzuki, N Shimada, K Chiba, T Ishizaki, CE Green, CA Tyson, T Yokoi, T Kamataki, Y Sugiyama

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 282(2) 909-919 1997年8月
Frequencies of the defective CYP2C19 alleles responsible for the mephenytoin poor metabolizer phenotype in various Oriental, Caucasian, Saudi Arabian and American black populations

JA Goldstein, T Ishizaki, K Chiba, SMF deMorais, D Bell, PM Krahn, DAP Evans

PHARMACOGENETICS 7(1) 59-64 1997年2月
Identification of cytochrome p450 isoforms involved in citalopram N-demethylation by human liver microsomes

K Kobayashi, K Chiba, T Yagi, N Shimada, T Taniguchi, T Horie, M Tani, T Yamamoto, T Ishizaki, Y Kuroiwa

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 280(2) 927-933 1997年2月
Mutual inhibition between quinine and etoposide by human liver microsomes : Evidence for cytochrome P450 3A4 involvement in thier major metabolic pathways

Drug Metabolism and Disposition 26(2) 188-191 1997年

石崎高志

基本情報

研究キーワード

研究分野

学歴

委員歴

受賞

MISC

所属学協会

共同研究・競争的資金等の研究課題

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