INUKAI Takeshi

J-GLOBAL         Last updated: Nov 20, 2018 at 10:56
 
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Name
INUKAI Takeshi
Affiliation
University of Yamanashi
Section
Department of Research Interdisciplinary Graduate School of Medicine and Engineering, Clinical Medical Science, Department of Pediatrics
Degree
(BLANK)(Yamanashi Medical University)

Research Interests

 
 

Research Areas

 
 

Academic & Professional Experience

 
1994
 - 
1997
St. Jude Children's Research Hospital,
 
 
   
 
Research Fellow
 

Education

 
 
 - 
1987
Faculty of Medicine, Yamanashi Medical University
 

Published Papers

 
Copy number abnormality of acute lymphoblastic leukemia cell lines based on their genetic subtypes.
Tomoyasu C, Imamura T, Tomii T, Yano M, Asai D, Goto H, Shimada A, Sanada M, Iwamoto S, Takita J, Minegishi M, Inukai T, Sugita K, Hosoi H.
Int J Hematol   108(3) 312-318   Sep 2018   [Refereed]
Notch1 activation enhances proliferation via activation of cdc2 and delays differentiation of myeloid progenitors.
Nakamura M, Wu L, Griffin JD, Kojika S, Goi K, Inukai T, Sugita K.
Leuk Res   72 34-44   Sep 2018   [Refereed]
Recurrent RARB Translocations in Acute Promyelocytic Leukemia Lacking RARA Translocation.
Osumi T, Tsujimoto SI, Tamura M, Uchiyama M, Nakabayashi K, Okamura K, Yoshida M, Tomizawa D, Watanabe A, Takahashi H, Hori T, Yamamoto S, Hamamoto K, Migita M, Ogata-Kawata H, Uchiyama T, Kizawa H, Ueno-Yokohata H, Shirai R, Seki M, Ohki K, Takita J, Inukai T, Ogawa S, Kitamura T, Matsumoto K, Hata K, Kiyokawa N, Goyama S, Kato M.
Cancer Res   78(16) 4452-4458   Aug 2018   [Refereed]
T315I mutation of BCR-ABL1 into human Philadelphia chromosome-positive leukemia cell lines by homologous recombination using the CRISPR/Cas9 system.
Tamai M, Inukai T, Kojika S, Abe M, Kagami K, Harama D, Shinohara T, Watanabe A, Oshiro H, Akahane K, Goi K, Sugihara E, Nakada S, Sugita K.
Sci Rep   8(1) 9966   Jul 2018   [Refereed]
Treatment outcome of children with acute lymphoblastic leukemia: the Tokyo Children's Cancer Study Group (TCCSG) Study L04-16.
Takahashi H, Kajiwara R, Kato M, Hasegawa D, Tomizawa D, Noguchi Y, Koike K, Toyama D, Yabe H, Kajiwara M, Fujimura J, Sotomatsu M, Ota S, Maeda M, Goto H, Kato Y, Mori T, Inukai T, Shimada H, Fukushima K, Ogawa C, Makimoto A, Fukushima T, Ohki K, Koh K, Kiyokawa N, Manabe A, Ohara A.
Int J Hematol   108(1) 98-108   Jun 2018   [Refereed]
Clofarabine exerts antileukemic activity against cytarabine-resistant B-cell precursor acute lymphoblastic leukemia with low deoxycytidine kinase expression.
Huang M, Inukai T, Miyake K, Tanaka Y, Kagami K, Abe M, Goto H, Minegishi M, Iwamoto S, Sugihara E, Watanabe A, Somazu S, Shinohara T, Oshiro H, Akahane K, Goi K, Sugita K.
Cancer Med   7(4) 1297-1316   Apr 2018   [Refereed]
Huang M, Inukai T, Kagami K, Abe M, Shinohara T, Watanabe A, Somazu S, Oshiro H, Goi K, Goto H, Minegishi M, Iwamoto S, Urayama KY, Sugita K.
Hematol Oncol   36(1) 245-251   Feb 2018   [Refereed]
Regional evaluation of childhood acute lymphoblastic leukemia genetic susceptibility loci among Japanese.
Urayama KY, Takagi M, Kawaguchi T, Matsuo K, Tanaka Y, Ayukawa Y, Arakawa Y, Hasegawa D, Yuza Y, Kaneko T, Noguchi Y, Taneyama Y, Ota S, Inukai T, Yanagimachi M, Keino D, Koike K, Toyama D, Nakazawa Y, Kurosawa H, Nakamura K, Moriwaki K, Goto H, Sekinaka Y, Morita D, Kato M, Takita J, Tanaka T, Inazawa J, Koh K, Ishida Y, Ohara A, Mizutani S, Matsuda F, Manabe A.
Sci Rep   8(1) 789   Jan 2018   [Refereed]
Anti-leukemic activity of bortezomib and carfilzomib on B-cell precursor ALL cell lines.
Takahashi K, Inukai T, Imamura T, Yano M, Tomoyasu C, Lucas DM, Nemoto A, Sato H, Huang M, Abe M, Kagami K, Shinohara T, Watanabe A, Somazu S, Oshiro H, Akahane K, Goi K, Kikuchi J, Furukawa Y, Goto H, Minegishi M, Iwamoto S, Sugita K.
PLoS One   12(12) e0188680   Dec 2017   [Refereed]
Tamai M, Furuichi Y, Kasai S, Ando N, Harama D, Goi K, Inukai T, Kagami K, Abe M, Ichikawa H, Sugita K.
Leuk Res   61 68-76   Oct 2017   [Refereed]
Huang M, Miyake K, Kagami K, Abe M, Shinohara T, Watanabe A, Somazu S, Oshiro H, Goi K, Goto H, Minegishi M, Iwamoto S, Kiyokawa N, Sugita K, Inukai T.
Leuk Res   60 24-30   Sep 2017   [Refereed]
Autologous Stem Cell Rescue for Graft Failure of Second Allogeneic Stem Cell Transplant After Engraftment of Primary Allogeneic Transplant.
Watanabe A, Inukai T, Akahane K, Somazu S, Oshiro H, Goi K, Koizumi K, Harii N, Matsuda K, Sugita K.
Exp Clin Transplant      Jul 2017   [Refereed]
Inflammatory mediator ultra-low-molecular-weight hyaluronan triggers necrosis of B-precursor leukemia cells with high surface CD44 expression.
Kasai S, Furuichi Y, Ando N, Kagami K, Abe M, Nakane T, Goi K, Inukai T, Saitoh S, Ohno S, Okazaki S, Nagano O, Saya H, Sugita K.
Cell Death Dis   8(6) e2857   Jun 2017   [Refereed]
Long-term outcome of 6-month maintenance chemotherapy for acute lymphoblastic leukemia in children.
Kato M, Ishimaru S, Seki M, Yoshida K, Shiraishi Y, Chiba K, Kakiuchi N, Sato Y, Ueno H, Tanaka H, Inukai T, Tomizawa D, Hasegawa D, Osumi T, Arakawa Y, Aoki T, Okuya M, Kaizu K, Kato K, Taneyama Y, Goto H, Taki T, Takagi M, Sanada M, Koh K, Takita J, Miyano S, Ogawa S, Ohara A, Tsuchida M, Manabe A.
Leukemia   31(3) 580-584   Mar 2017   [Refereed]
Piao J, Takai S, Kamiya T, Inukai T, Sugita K, Ohyashiki K, Delia D, Masutani M, Mizutani S, Takagi M.
Cancer Lett   386 131-140   Feb 2017   [Refereed]
Watanabe A, Akahane K, Somazu S, Oshiro H, Goi K, Miyachi H, Kiyokawa N, Inukai T, Sugita K.
J Clin Pathol.   69(12) 1129-1132   Dec 2016   [Refereed]
Sera Y, Yamasaki N, Oda H, Nagamachi A, Wolff L, Inukai T, Inaba T, Honda H.
Cancer Sci   107(7) 890-898   Jul 2016   [Refereed]
Nemoto A, Saida S, Kato I, Kikuchi J, Furukawa Y, Maeda Y, Akahane K, Honna-Oshiro H, Goi K, Kagami K, Kimura S, Sato Y, Okabe S, Niwa A, Watanabe K, Nakahata T, Heike T, Sugita K, Inukai T.
Mol Cancer Ther   15(1) 94-105   Jan 2016   [Refereed]
Wu Z, Eguchi-Ishimae M, Yagi C, Iwabuki H, Gao W, Tauchi H, Inukai T, Sugita K, Ishii E, Eguchi M.
Br J Haematol   171(5) 818-829   Dec 2015   [Refereed]
Tomizawa D, Kato M, Takahashi H, Fujimura J, Inukai T, Fukushima T, Kiyokawa N, Koh K, Manabe A, Ohara A.
Int J Hematol   102(5) 602-610   Nov 2015   [Refereed]

Misc

 
Nuclear accumulation of B-catenin without an additional somatic mutation in coding region of APC gene in hepatoblastoma from a familiar adenomatous polyposis patient
Oncology Reports   11(1) 121   2004
Participation of granuloceyte-colony stimulating factor in the growth regulation of leukemia cells from Philadelphia chromosome-positive acute leukemia and blast crisis of chronic myeloid leukemia
Leukemia   14 1386   2000
The AD1 and AD2 Transactivation Domains of E2A Are Essential for the Antiapoptotic Activity of the Chimeric Oncoprotein EZA-HLF
Molecular and Cellular Biology   18(10) 6035   1998

Conference Activities & Talks

 
Molecular aspects of chemoresistance in childhood acute lymphoblastic leukemia [Invited]
INUKAI Takeshi
4th International Postgraduate Conference on Pharmaceutical Sciences 2016   2016   

Research Grants & Projects

 
Study on Apoptosis in Hematopoietic and Leukemic Cell.
Grant-in-Aid for Scientific Research
Project Year: 1998