三木裕明 (Hiroaki Miki) - マイポータル

基本情報

所属: 京都大学大学院工学研究科教授

学位: 博士（理学）(1998年3月東京大学)

研究者番号: 80302602
J-GLOBAL ID: 200901017509075164
researchmap会員ID: 1000255202

経歴

学歴

1993年4月 - 1998年3月

東京大学, 大学院理学系研究科, 生物化学専攻
1991年4月 - 1993年3月

東京大学, 理学部, 生物化学科

論文

129

Phosphatase‐independent role of phosphatase of regenerating liver in cancer progression

Yosuke Funato, Osamu Hashizume, Hiroaki Miki

Cancer Science 114(1) 25-33 2023年1月査読有り最終著者責任著者
PRL stimulates mitotic errors by suppressing kinetochore-localized activation of AMPK during mitosis

Kajung Ryu, Atsushi Yoshida, Yosuke Funato, Daisuke Yamazaki, Hiroaki Miki

Cell Structure and Function 47(2) 75-87 2022年12月査読有り最終著者
A novel role for PRL in regulating epithelial cell density by inducing apoptosis at confluence.

Sweksha Lohani, Yosuke Funato, Yuki Akieda, Kiyohito Mizutani, Yoshimi Takai, Tohru Ishitani, Hiroaki Miki

Journal of cell science 135(2) :jcs258550 2022年1月15日査読有り最終著者責任著者
The emerging roles and therapeutic potential of cyclin M/CorC family of Mg2+ transporters.

Yosuke Funato, Hiroaki Miki

Journal of pharmacological sciences 148(1) 14-18 2022年1月査読有り招待有り最終著者責任著者
Gut bacteria identified in colorectal cancer patients promote tumourigenesis via butyrate secretion.

Shintaro Okumura, Yusuke Konishi, Megumi Narukawa, Yuki Sugiura, Shin Yoshimoto, Yuriko Arai, Shintaro Sato, Yasuo Yoshida, Shunya Tsuji, Ken Uemura …

Nature communications 12(1) 5674-5674 2021年9月28日査読有り
Importance of the renal ion channel TRPM6 in the circadian secretion of renin to raise blood pressure.

Yosuke Funato, Daisuke Yamazaki, Daisuke Okuzaki, Nobuhiko Yamamoto, Hiroaki Miki

Nature communications 12(1) 3683-3683 2021年6月17日査読有り最終著者責任著者
Identification and mechanistic analysis of an inhibitor of the CorC Mg2+ transporter

Yichen Huang, Kaijie Mu, Xinyu Teng, Yimeng Zhao, Yosuke Funato, Hiroaki Miki, Weiliang Zhu, Zhijian Xu, Motoyuki Hattori

iScience 24(4) 102370-102370 2021年4月査読有り
Phosphatase, pseudo-phosphatase, or both? Understanding PRL oncogenicity

Kalle Gehring, Hiroaki Miki

British Journal of Cancer 124(6) 1035-1036 2021年3月16日査読有り最終著者
Role of adenomatous polyposis coli in proliferation and differentiation of colon epithelial cells in organoid culture

Daisuke Yamazaki, Osamu Hashizume, Shiho Taniguchi, Yosuke Funato, Hiroaki Miki

Scientific Reports 11(1) 3980 2021年2月17日査読有り最終著者責任著者
Structural basis for the Mg²⁺ recognition and regulation of the CorC Mg²⁺ transporter

Yichen Huang, Fei Jin, Yosuke Funato, Zhijian Xu, Weiliang Zhu, Jing Wang, Minxuan Sun, Yimeng Zhao, Ye Yu, *Hiroaki Miki (co-correspondence) …

Science Advances 7(7) eabe6140 2021年2月10日査読有り責任著者
Magnesium efflux from Drosophila Kenyon cells is critical for normal and diet-enhanced long-term memory

Yanying Wu, Yosuke Funato, Eleonora Meschi, Kristijan D Jovanoski, Hiroaki Miki, Scott Waddell

eLife 9 e61339 2020年11月26日査読有り
The Oncogenic PRL Protein Causes Acid Addiction of Cells by Stimulating Lysosomal Exocytosis

Yosuke Funato, Atsushi Yoshida, Yusuke Hirata, Osamu Hashizume, Daisuke Yamazaki, Hiroaki Miki

Developmental Cell 55(4) 387-397.e8 2020年11月23日査読有り最終著者責任著者
PRL3 pseudophosphatase activity is necessary and sufficient to promote metastatic growth

Guennadi Kozlov, Yosuke Funato, Yu Seby Chen, Zhidian Zhang, Katalin Illes, Hiroaki Miki, Kalle Gehring

Journal of Biological Chemistry 295(33) 11682-11692 2020年8月14日査読有り
Excessive Mg²⁺ Impairs Intestinal Homeostasis by Enhanced Production of Adenosine Triphosphate and Reactive Oxygen Species

Osamu Hashizume, Yosuke Funato, Daisuke Yamazaki, Hiroaki Miki

Antioxidants and Redox Signaling 33(1) 20-34 2020年7月1日査読有り最終著者責任著者
Stress-responsive MTK1 SAPKKK serves as a redox sensor that mediates delayed and sustained activation of SAPKs by oxidative stress

Moe Matsushita, Takanori Nakamura, Hisashi Moriizumi, Hiroaki Miki, Mutsuhiro Takekawa

Science Advances 6(26) eaay9778 2020年6月査読有り
P18/lamtor1-mtorc1 signaling controls development of mucin-producing goblet cells in the intestine

Shizuka Ito, Shigeyuki Nada, Daisuke Yamazaki, Tetsuya Kimura, Kentaro Kajiwara, Hiroaki Miki, Masato Okada

Cell Structure and Function 45(2) 93-105 2020年査読有り
Control of protein function through oxidation and reduction of persulfidated states

Dóka, T. Ida, M. Dagnell, Y. Abiko, N. C. Luong, N. Balog, T. Takata, B. Espinosa, A. Nishimura, Q. Cheng …

Science Advances 6(1) eaax8358 2020年1月1日査読有り
Phosphatase of regenerating liver sensitizes MET to functional activation by hepatocyte growth factor

Takuya Kojima, Yosuke Funato, Hiroaki Miki

Biochemical Journal 476(10) 1419-1431 2019年5月21日査読有り最終著者責任著者
Cnnm4 deficiency suppresses Ca²⁺ signaling and promotes cell proliferation in the colon epithelia

Daisuke Yamazaki, Ayaka Hasegawa, Yosuke Funato, Ha Nam Tran, Masayuki X. Mori, Yasuo Mori, Toshiro Sato, Hiroaki Miki

Oncogene 38(20) 3962-3969 2019年5月16日査読有り最終著者責任著者
Molecular function and biological importance of CNNM family Mg ²⁺ transporters

Yosuke Funato, Hiroaki Miki

Journal of Biochemistry 165(3) 219-225 2019年3月1日査読有り最終著者責任著者

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