IMAKAWA Kazuhiko

J-GLOBAL         Last updated: Sep 23, 2019 at 12:30
 
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Name
IMAKAWA Kazuhiko
E-mail
ik459102tsc.u-tokai.ac.jp
Affiliation
Tokai University
Section
Research Institute of Agriculture
Degree
Ph.D.(University of Nebraska (U. S. A))

Research Areas

 
 

Academic & Professional Experience

 
1995
 - 
1997
Associate professor, Department of Pathlogy and Laboratory Medicine, University of Kansas Medical Center
 
1997
   
 
- The University of Tokyo, Vet. Med. Sci. Animal
 
1989
 - 
1995
Assistant Professor, University of Kansas School of Medicine
 
 
   
 
Breeding
 
1995
 - 
1997
Univ of Kansas medical Center. Dept of
 

Education

 
 
 - 
1984
Reproductive Endocrinology, Graduate School, Division of Animal Sciences, University of Nebraska U. S. A.
 
 
 - 
1975
Faculty of Agriculture, Ibaraki University
 

Committee Memberships

 
1998
   
 
The Japanese Society of Animal Reproduction  Advisory Board
 

Published Papers

 
Choi SA, Kim YH, Park YH, Yang HJ, Jeong PS, Cha JJ, Yoon SB, Kim JS, Song BS, Lee JH, Sim BW, Huh JW, Song IS, Lee SR, Kim MK, Kim JM, Bae YS, Imakawa K, Kim SU, Chang KT
Cell death and differentiation   26(9) 1582-1599   Sep 2019   [Refereed]
Kobayashi T, Inagaki Y, Ohnuki N, Sato R, Murakami S, Imakawa K
Preventive veterinary medicine      May 2019   [Refereed]
Ezz MA, Marey MA, Elweza AE, Kawai T, Heppelmann M, Pfarrer C, Balboula AZ, Montaser A, Imakawa K, Zaabel SM, Shimada M, Miyamoto A
PloS one   14(4) e0214516   2019   [Refereed]
Talukder AK, Rashid MB, Takedomi T, Moriyasu S, Imakawa K, Miyamoto A
American journal of reproductive immunology (New York, N.Y. : 1989)   81(2) e13069   Oct 2018   [Refereed]
Fujiwara H, Matsumoto H, Sato Y, Horie A, Ono M, Nakamura M, Mizumoto Y, Kagami K, Fujiwara T, Hattori A, Maida Y, Daikoku T, Imakawa K, Araki Y
Current pharmaceutical biotechnology   19(10) 764-770   Oct 2018   [Refereed]
Kusama K, Bai R, Imakawa K
Journal of cellular biochemistry   119(6) 4918-4927   Jun 2018   [Refereed]
Bai R, Kusama K, Nakamura K, Sakurai T, Kimura K, Ideta A, Aoyagi Y, Imakawa K
FASEB journal : official publication of the Federation of American Societies for Experimental Biology   32(6) 3371-3384   Jun 2018   [Refereed]
Rashid MB, Talukder AK, Kusama K, Haneda S, Takedomi T, Yoshino H, Moriyasu S, Matsui M, Shimada M, Imakawa K, Miyamoto A
Biochemical and biophysical research communications   500(4) 879-884   Jun 2018   [Refereed]
Kusama K, Tamura K, Bai H, Sakurai T, Nishi H, Isaka K, Imakawa K, Yoshie M
Reproduction, fertility, and development   30(11) 1454-1461   May 2018   [Refereed]
Talukder AK, Rashid MB, Yousef MS, Kusama K, Shimizu T, Shimada M, Suarez SS, Imakawa K, Miyamoto A
Scientific reports   8(1) 7850   May 2018   [Refereed]
Elweza AE, Ezz MA, Acosta TJ, Talukder AK, Shimizu T, Hayakawa H, Shimada M, Imakawa K, Zaghloul AH, Miyamoto A
Molecular reproduction and development   85(3) 215-226   Mar 2018   [Refereed]
Kim MS, Min KS, Seong HH, Kim CL, Jeon IS, Kim SW, Imakawa K
Animal reproduction science   190 39-46   Mar 2018   [Refereed]
Kusama K, Nakamura K, Bai R, Nagaoka K, Sakurai T, Imakawa K
Biochemical and biophysical research communications   495(1) 1370-1375   Jan 2018   [Refereed]

Misc

 
中川草, 中川草, 上田真保子, 今川和彦, 宮沢孝幸
日本進化学会大会プログラム・講演要旨集(Web)   20th 88 (WEB ONLY)   Aug 2018
稲垣靖子, 小林朋子, 須田義人, 今川和彦
畜産の研究   71(11) 917‐923   Nov 2017
稲垣靖子, 須田義人, 小林朋子, 草間和哉, 今川和彦
日本畜産学会大会講演要旨   123rd 111   Sep 2017
中村圭吾, 草間和哉, 白汝嵐, 須田義人, 今川和彦
日本生殖内分泌学会雑誌   22 39‐47   Aug 2017
白汝嵐, 草間和哉, 櫻井敏博, 今川和彦
日本畜産学会大会講演要旨   122nd 162   Mar 2017
李俊佑, 飯塚祐彦, 池田正則, 長谷川茂樹, 今川和彦
日本畜産学会大会講演要旨   122nd 161   Mar 2017
草間和哉, 白汝嵐, 出田篤司, 青柳敬人, 今川和彦
日本畜産学会大会講演要旨   122nd 162   Mar 2017
草間和哉, 今川和彦
日本はい移植学雑誌   38(3) 123‐129   Sep 2016
中村圭吾, 草間和哉, 白汝嵐, 今川和彦
日本畜産学会大会講演要旨   121st 146   Mar 2016
白汝嵐, 櫻井敏博, 唄花子, 久世真理子, 出田篤司, 青柳敬人, 奥田潔, 今川和彦
関東畜産学会大会講演要旨集   68th 50   Nov 2013
唄花子, 櫻井敏博, 藤原浩, 出田篤司, 青柳敬人, 今川和彦
日本畜産学会報   84(3) 301-308   Aug 2013
江頭真宏, 廣田泰, 藤田知子, 原口広史, 松本玲央奈, 松尾光徳, 大須賀穣, 藤井知行, 今川和彦, 前多敬一郎
J Reprod Dev   59(Suppl Japanese Issue) J72   Aug 2013
今川和彦, 宮沢孝幸
J Mamm Ova Res   30(2) S34   Apr 2013
唄花子, 櫻井敏博, 青木悦成, 中川草, 仲屋友喜, 宮沢孝幸, 出田篤司, 青柳敬人, 五篠堀孝, 今川和彦
日本畜産学会大会講演要旨   116th 97   Mar 2013
白汝嵐, 櫻井敏博, 唄花子, 荒井未来, 出田篤司, 青柳敬人, 奥田潔, 今川和彦
日本畜産学会大会講演要旨   116th 94   Mar 2013
櫻井敏博, 唄花子, 荒井未来, 奥田潔, 今川和彦
日本畜産学会大会講演要旨   116th 179   Mar 2013
今川和彦, 安田二朗, 宮沢孝幸
日本獣医学会学術集会講演要旨集   155th 146   Mar 2013
中村雄気, 出田篤司, 白澤篤, 波山功, 酒井伸一, 浦川真実, 今川和彦, 青柳敬人
東日本家畜受精卵移植技術研究会大会資料   29th 57   2013
唄花子, 櫻井敏博, 染谷洋平, 今川和彦
日本受精着床学会雑誌   29(2) 275-282   Jul 2012
Ovine trophoblast protein-1, a major secretory product of embryonic trophectoderm has sequence similarity to interferons. (共著)
Nature   330 377   1987
Molecular cloning and cellular localization of unique interferons from human placenta. (共著)
Journal of Biological Chemistry   269 10864   1994
The influence of dietary energy intake on progesterone concentrations in beef heifers. (共著)
J Anim Sci   56 454   1981
(1983)Influence of exposure to bulls on resumption of estrous cycles following parturition in beef cows. (共著)
J Anim Sci   59 1135   1983
Effects of copulation on timing of the LH surge following synchronization of estrus in the bovine. (共著)
Theriogeneology   23 663   1983
Luteinizing hormone secretion following withdrawal of exogenous progestin in heifers fed three levels of dietary energy. (共著)
J Anim Sci   58 151   1984
Endocrine mechanisms of puberty in heifers ; Estradiol negative feedback regulation of luteinizing hormone secretion. (共著)
Biol Reprod   31 332   1984
Effect of suckling and ovariectomy on the control of luteinizing hormone secretion during the postpartum period in beef cows. (共著)
Biol Reprod   31 771-778   1984
Endocrine changes during restoration of estrous cycles following induction of anestrus by restricted nutrient intake in beef heifers. (共著)
J Anim Sci   63 565-571   1986
Influence of dietary-induced weight changes on serum luteinizing hormone, estrogen and progesterone in the bovine female. (共著)
Biol Reprod   35 377-384   1986
Regulation of pulsatile LH secretion by ovarian steroids in the heifer. (共著)
J Anim Sci   63 162-168   1986
Influence of prepubertal ovariectomy and estradiol replacement therapy on secretion of luteinizing hormone before and after pubertal age in heifers. (共著)
Dom Anim Endocrinol   3 17-25   1986
Effects of suckling and low doses of estradiol on luteinizing hormone secretion during the postpartum period in beef cows. (共著)
Dom Anim Endocrinol   3 79-86   1986
Effects of restriction of dietary energy intake during the prepubertal period on secretion of luteinizing hormone and responsiveness of the pituitary to luteinizing hormone-releasing hormone in heifers. (共著)
J Anim Sci   62 1641-1648   1986
Influence of season and estradiol on secretion of luteinizing hormone in ovariectomized cows. (共著)
Biol Reprod   35 549-553   1986
Effects of 17β-estradiol on diets varying in energy on secretion of luteinizing hormone in beef heifers. (共著)
J Anim Sci   64 805-815   1987
Suckling behavior of calves with damp varying milk production. (共著)
J Anim Sci   65 1207-1212   1987
Endocrine mechanisms of puberty in heifers. Role of hypothalami-pituitary estradiol receptors in the negative feedback of estradiol on estradiol on luteinizing hormone secretion. (共著)
Biol Reprod   37 1054-1065   1987
Interferon RNA of embryonic origin is expressed transiently during early pregnancy in the ewe. (共著)
J Biol Chem   263 12801-12804   1988
The conceptus protein responsible for maternal recognition of pregnancy in the sheep has functional properties of an interferon alpha. (共著)
J Interferon Res   9 175-187   1989
Molecular cloning and characterization of cDNAs corresponding to bovine trophoblast protein-1. A comparison with ovine trophoblast protein-1 and bovine interferon αII. (共著)
Molecular Endocrinol   3 127-139   1989
Complex binding of the embryonic interferon, ovine trophoblast protein-1, to endometrial receptors. (共著)
J Interferon Res   9 215-225   1989
In situ localization of mRNA for the interferon, ovine trophoblast protein-1, during early embryonic development of the sheep. (共著)
Molecular Endocrinol   3 1099-1107   1989
Suppression of T-lymphocyte blastogenesis by ovine trophoblast protein-1 and human interferon-α may be independent of interleukin-2 production. (共著)
Am J Reprod Immunol   20 21-26   1989
Molecular cloning of the uteroferrin-associated protein, a major progesterone-induced serpin secreted by the porcine uterus, and the expression of its mRNA during pregnancy. (共著)
Molecular Endocrinol   4 428-440   1990
Interferons at the placental interface. (共著)
J Reprod Fert, Suppl   41 63-74   1990
Expression of embryonic interferon genes in sheep and cattle. (共著)
Biol Reprod   43 210-218   1990
The production, purification, and bioactivity of recombinant bovine trophoblast protein-1(bovine trophoblast interferon). (共著)
Molecular Endocrinol   4 1506-1514   1990
Slowed transcription and rapid mRNA turnover contribute to a decline in synthesis of ovine trophoblast protein-1 during in vitro culture. (共著)
Biol Reprod   45 94-100   1991
The polypeptides and genes for ovine and bovine trophoblast protein-1. (共著)
J Reprod Fert Suppl   43 3-12   1991
Circulating concentrations of 17β-estradiol influence patterns of LH in circulation of cows. (共著)
Domestic Animal Endocrinol   8 463-469   1991
Molecular cloning and analysis of an ovine interferon alpha II gene. (共著)
Gene   106 281   1991
Evidence for lipopolysaccharide binding in human granulosa-luteal cells : stimulation of tumor necrosis factor-α secretion. (共著)
J Endocrinol   135 571-578   1992
Expression of tumor necrosis factor-α in the rat ovary. (共著)
Endocrinology   130 1359-1364   1992
Detection of mRNA for inhibin α- and β-subunits in bovine ovarian tissues and the effects of in vivo administration of GnRH. (共著)
Domestic Animal Endocrinol   10 207-218   1993
Differential expression of distinct mRNAs for ovine trophoblast protein-1 and related sheep type I interferons. (共著)
Biol Reprod   48 768-778   1993
A novel role for GM-CSF : Enhancement of pregnancy specific interferon production, ovine trophoblast protein-1. (共著)
Endocrinology   132 1869-1871   1993
Molecular cloning and cellular localization of unique interferons from human placenta. (共著)
J Biol Chem   269 10864-10868   1994
Effects of Interleukin-3 on ovine trophoblast interferon during early conceptus development. (共著)
Endocrine   3 511-517   1995
Differential expression of Hβ58 in the chorioallantoic placenta. (共著)
Biology of Reproduction   63 1735-1746   2000
HIROHITO YAMAGUCHI, YASUHIRO IKEDA, ALAN TAYLOR, MOMOKO KATSUMURA, TAKAYUKI MIYAZAWA, EIJI TAKAHASHI, KAZUHIKO IMAKAWA, SENKITI SAKAI
Endocrine Journal   46(3) 383-388   1999
Hiroki Aida, Hirohiro Yamaaguchi, Momoko Katsumura, Kazuhiko Imakawa, Senkiti Sakai
J Reproduction and Development   45(4) 249-257   1999
Journal of Reproduction and Development   47(2) 69-82   2001
Implantation in ruminants : Changes in pre-implantation, maternal recognition of pregnancy, contrail of attachment and invasion-Review(共著)
Asian-Aus. J. Animal Science   13 845-855   2000
Identification of negative regulatory regions of interferon-tau gene(共著)
Endocrine Journal   47 137-142   2000
Establishment of feeder-independent cloned Caprine Twphoblast cell lone which expresses placental lactogen and interferon-tan(共著) .
Plocanta   23, 613-630 
Regulation of endometrial granulocyte macrophage colony stimulating factor (GM-CSF) in the ewe.
Domest Animal Endocrinal   48, 523-529 

Books etc

 
Genetics and Animal Breeding
IMAKAWA Kazuhiko (Part:Joint Work, Editor)
May 2014   
Interferons and maternal recognition of pregnancy. (共著)
In : Development of preimplantation embryos and their environment   1988   
Embryonic interferons and maternal recognition of pregnancy. (共著)
In : Biology of the interferon system 1988   1989   
Embryonic mediators of maternal recognition of pregnancy. (共著)
In : Blastocyst implantation, Serono Symposia, USA, Adams Publishing Group, Ltd, Boston, MA   1989   
The polypeptides and genes of ovine and bovine trophoblast protein-1. (共著)
Intn'l Ruminant Reproduction Symposium : J Reprod Fert Supplement.   1990   

Conference Activities & Talks

 
Integration of molecules to construct the processes of conceptus implantation to the maternal endometrium [Invited]
IMAKAWA Kazuhiko
ASAS-SSR Triennial Reproduction Symposium   13 Jul 2017   

Works

 
Development of early pregnancy detection method
2001
Use of Chemokine in enhancing reproductive efficiency
2001
Mechanisms of development in Crohn's and Johes diseases
2001

Research Grants & Projects

 
Biology of implantation : Prevention of embryonic loss
Regulation of interferon-tau gene expression
IFN expression and viral resistant animals

Patents

 
Detergent composition providing rinse cycle suds control. 特許US/23.01.86/US821669
*
Use of interferons of the alpha family to enhance fertility in mammals 特許US07/312,853
*
Human trophoblast derived interferon and methods of use. 特許US
*