2015年6月11日
Uncaging a catalytic hydrogen peroxide generator through the photo-induced release of nitric oxide from a {MnNO}6 complex
Chemical Communications
- ,
- ,
- 巻
- 51
- 号
- 46
- 開始ページ
- 9539
- 終了ページ
- 9542
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1039/c5cc02566d
- 出版者・発行元
- ROYAL SOC CHEMISTRY
© The Royal Society of Chemistry 2015. The photo-initiated cytotoxicity of a newly developed manganese nitrosyl {MnNO}6 complex (UG1NO) to HeLa cells is described. The complex was found to be strongly cytotoxic after being exposed to light with a wavelength of 650 nm. Cell death was caused by a manganese(II) complex, UG1, generated from UG1NO through the photo-dissociation of NO, rather than by NO directly. Mechanistic studies revealed that UG1 consumes O2 only in the presence of a reducing agent to catalytically produce H2O2.
- リンク情報
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- DOI
- https://doi.org/10.1039/c5cc02566d
- PubMed
- https://www.ncbi.nlm.nih.gov/pubmed/25967395
- Web of Science
- https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000355345700029&DestApp=WOS_CPL
- URL
- http://www.scopus.com/inward/record.url?eid=2-s2.0-84930226133&partnerID=MN8TOARS
- Scopus Citedby
- https://www.scopus.com/inward/citedby.uri?partnerID=HzOxMe3b&scp=84930226133&origin=inward
- ID情報
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- DOI : 10.1039/c5cc02566d
- ISSN : 1359-7345
- eISSN : 1364-548X
- ORCIDのPut Code : 20118598
- PubMed ID : 25967395
- SCOPUS ID : 84930226133
- Web of Science ID : WOS:000355345700029