論文

査読有り
2016年

Screening of a virtual mirror-image library of natural products

CHEMICAL COMMUNICATIONS
  • Taro Noguchi
  • ,
  • Shinya Oishi
  • ,
  • Kaori Honda
  • ,
  • Yasumitsu Kondoh
  • ,
  • Tamio Saito
  • ,
  • Hiroaki Ohno
  • ,
  • Hiroyuki Osada
  • ,
  • Nobutaka Fujii

52
49
開始ページ
7653
終了ページ
7656
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1039/c6cc03114e
出版者・発行元
ROYAL SOC CHEMISTRY

We established a facile access to an unexplored mirror-image library of chiral natural product derivatives using D-protein technology. In this process, two chemical syntheses of mirror-image substances including a target protein and hit compound(s) allow the lead discovery from a virtual mirror-image library without the synthesis of numerous mirror-image compounds.

リンク情報
DOI
https://doi.org/10.1039/c6cc03114e
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/27198617
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000378236500002&DestApp=WOS_CPL
ID情報
  • DOI : 10.1039/c6cc03114e
  • ISSN : 1359-7345
  • eISSN : 1364-548X
  • PubMed ID : 27198617
  • Web of Science ID : WOS:000378236500002

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