Treatment of optically active 3-alkyl-2-vinylaziridines 1, 8 and 9 and allylic acetates 10 and 11 with InI in the presence of Pd(PPh3)(4) gives rise to chiral allylindiums bearing an amino group at the delta -position, which react with several aldehydes in highly regio- and stereoselective manner to afford the syn,syn-2-vinyl-1,3-amino alcohols 2a, 5a-7a and 12a-14a possessing three contiguous chiral centers in good yields. (C) 2001 Elsevier Science Ltd. All rights reserved.