2002年2月
Synthesis of allenes from allylic alcohol derivatives bearing a bromine atom using a palladium(0)/diethylzinc system
JOURNAL OF ORGANIC CHEMISTRY
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- 巻
- 67
- 号
- 4
- 開始ページ
- 1359
- 終了ページ
- 1367
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1021/jo016320y
- 出版者・発行元
- AMER CHEMICAL SOC
A general and efficient synthesis of allenes using a palladium(0)/diethylzine system is described. Treatment of mesylates or trichloroacetates of (E)- or (Z)-2-bromoalk-2-en-1-ols with diethylzinc in the presence of a catalytic amount of palladium(0) affords allenes bearing an aminoalkyl, alkyl, or aryl substituent(s) in good to high yields. No transfer of chirality from the stereogenic center carrying the mesyloxy group to the allene was observed.
- リンク情報
- ID情報
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- DOI : 10.1021/jo016320y
- ISSN : 0022-3263
- PubMed ID : 11846687
- Web of Science ID : WOS:000173901700045