2012年1月
Gold-Catalyzed Three-Component Annulation: Efficient Synthesis of Highly Functionalized Dihydropyrazoles from Alkynes, Hydrazines, and Aldehydes or Ketones
ORGANIC LETTERS
- ,
- ,
- ,
- ,
- 巻
- 14
- 号
- 1
- 開始ページ
- 326
- 終了ページ
- 329
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1021/0l203072u
- 出版者・発行元
- AMER CHEMICAL SOC
Polysubstituted dihydropyrazoles were directly obtained by a gold-catalyzed three-component annulation. This reaction consists of a Mannich-type coupling of alkynes with N,N-disubstituted hydrazines and aldehydes/ketones followed by intramolecular hydroamination. Cascade cyclization using 1,2-dialkynylbenzene derivatives as the alkyne component was also performed producing fused tricyclic dihydropyrazoles in good yields.
- リンク情報
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- DOI
- https://doi.org/10.1021/0l203072u
- J-GLOBAL
- https://jglobal.jst.go.jp/detail?JGLOBAL_ID=201202269135815973
- PubMed
- https://www.ncbi.nlm.nih.gov/pubmed/22176630
- Web of Science
- https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000298828500084&DestApp=WOS_CPL
- ID情報
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- DOI : 10.1021/0l203072u
- ISSN : 1523-7060
- J-Global ID : 201202269135815973
- PubMed ID : 22176630
- Web of Science ID : WOS:000298828500084