Minoru Takahashi

Profile Information

Degree: 博士(医学)(大阪大学)

J-GLOBAL ID: 200901067269058710
researchmap Member ID: 1000269678

Research Interests

Research Areas

Research History

Associate Professor, Fukushima Medical University School of Medicine

Committee Memberships

Jun, 2014

理事, 日本補体学会
2013

運営委員, 補体研究会

Awards

2008

2008年度補体シンポジウム最優秀賞

Misc.

Essential Role for the Lectin Pathway in Collagen Antibody-Induced Arthritis Revealed through Use of Adenovirus Programming Complement Inhibitor MAp44 Expression

Nirmal K. Banda, Gaurav Mehta, Troels R. Kjaer, Minoru Takahashi, Jerome Schaack, Thomas E. Morrison, Steffen Thiel, William P. Arend, V. Michael Holers

JOURNAL OF IMMUNOLOGY, 193(5) 2455-2468, Sep, 2014
Essential Role for the Lectin Pathway in Collagen Antibody-Induced Arthritis Revealed through Use of Adenovirus Programming Complement Inhibitor MAp44 Expression

Nirmal K. Banda, Gaurav Mehta, Troels R. Kjaer, Minoru Takahashi, Jerome Schaack, Thomas E. Morrison, Steffen Thiel, William P. Arend, V. Michael Holers

JOURNAL OF IMMUNOLOGY, 193(5) 2455-2468, Sep, 2014
C3 dysregulation due to factor H deficiency is mannan-binding lectin-associated serine proteases (MASP)-1 and MASP-3 independent in vivo

M. M. Ruseva, M. Takahashi, T. Fujita, M. C. Pickering

CLINICAL AND EXPERIMENTAL IMMUNOLOGY, 176(1) 84-92, Apr, 2014
C3 dysregulation due to factor H deficiency is mannan-binding lectin-associated serine proteases (MASP)-1 and MASP-3 independent in vivo

M. M. Ruseva, M. Takahashi, T. Fujita, M. C. Pickering

CLINICAL AND EXPERIMENTAL IMMUNOLOGY, 176(1) 84-92, Apr, 2014
Roles of Adipocytes and Fibroblasts in Activation of the Alternative Pathway of Complement in Inflammatory Arthritis in Mice

William P. Arend, Gaurav Mehta, Alexandra H. Antonioli, Minoru Takahashi, Kazue Takahashi, Gregory L. Stahl, V. Michael Holers, Nirmal K. Banda

JOURNAL OF IMMUNOLOGY, 190(12) 6423-6433, Jun, 2013
Roles of Adipocytes and Fibroblasts in Activation of the Alternative Pathway of Complement in Inflammatory Arthritis in Mice

William P. Arend, Gaurav Mehta, Alexandra H. Antonioli, Minoru Takahashi, Kazue Takahashi, Gregory L. Stahl, V. Michael Holers, Nirmal K. Banda

JOURNAL OF IMMUNOLOGY, 190(12) 6423-6433, Jun, 2013
補体D因子の活性化とMASP-1

高橋実

臨床免疫・アレルギー科, 56(1) 78-83, 2011
MASP-1 contributes alternative pathway by activation of factor D.

Minoru Takahashi

Clinical Immunology & Allergology, 56(1) 78-83, 2011
Interactions of Ficolin and Mannose-Binding Lectin with Fibrinogen/Fibrin Augment the Lectin Complement Pathway

Yuichi Endo, Naomi Nakazawa, Daisuke Iwaki, Minoru Takahashi, Misao Matsushita, Teizo Fujita

JOURNAL OF INNATE IMMUNITY, 2(1) 33-42, 2010
Essential role of Mannose-binding lectin-associated serine protease-1 in activation of the complement factor D

Minoru Takahashi, Yumi Ishida, Daisuke Iwaki, Kazuko Kanno, Toshiyuki Suzuki, Yuichi Endo, Yoshimi Homma, Teizo Fujita

JOURNAL OF EXPERIMENTAL MEDICINE, 207(1) 29-37, Jan, 2010
Interactions of Ficolin and Mannose-Binding Lectin with Fibrinogen/Fibrin Augment the Lectin Complement Pathway

Yuichi Endo, Naomi Nakazawa, Daisuke Iwaki, Minoru Takahashi, Misao Matsushita, Teizo Fujita

JOURNAL OF INNATE IMMUNITY, 2(1) 33-42, 2010
Essential role of Mannose-binding lectin-associated serine protease-1 in activation of the complement factor D

Minoru Takahashi, Yumi Ishida, Daisuke Iwaki, Kazuko Kanno, Toshiyuki Suzuki, Yuichi Endo, Yoshimi Homma, Teizo Fujita

JOURNAL OF EXPERIMENTAL MEDICINE, 207(1) 29-37, Jan, 2010
Mannose-binding lectin (MBL)-associated serine protease (MASP)-1 contributes to activation of the lectin complement pathway

Minoru Takahashi, Daisuke Iwaki, Kazuko Kanno, Yumi Ishida, Jie Xiong, Misao Matsushita, Yuichi Endo, Shigeto Miura, Naoto Ishii, Kazuo Sugamura …

JOURNAL OF IMMUNOLOGY, 180(9) 6132-6138, May, 2008
Mannose-binding lectin (MBL)-associated serine protease (MASP)-1 contributes to activation of the lectin complement pathway

Minoru Takahashi, Daisuke Iwaki, Kazuko Kanno, Yumi Ishida, Jie Xiong, Misao Matsushita, Yuichi Endo, Shigeto Miura, Naoto Ishii, Kazuo Sugamura …

JOURNAL OF IMMUNOLOGY, 180(9) 6132-6138, May, 2008
Role of MBL-associated serine protease (MASP) on activation of the lectin complement pathway

Takahashi M, Mori S, Shigeta S, Fujita T

Advances in experimental medicine and biology, 598 93-104, 2007
Role of MBL-associated serine protease (MASP) on activation of the lectin complement pathway

Takahashi M, Mori S, Shigeta S, Fujita T

Advances in experimental medicine and biology, 598 93-104, 2007
Small mannose-binding lectin-associated protein plays a regulatory role in the lectin complement pathway

Daisuke Iwaki, Kazuko Kanno, Minoru Takahashi, Yuichi Endo, Nicholas J. Lynch, Wilhelm J. Schwaeble, Misao Matsushita, Masaru Okabe, Teizo Fujita

JOURNAL OF IMMUNOLOGY, 177(12) 8626-8632, Dec, 2006
Small mannose-binding lectin-associated protein plays a regulatory role in the lectin complement pathway

Daisuke Iwaki, Kazuko Kanno, Minoru Takahashi, Yuichi Endo, Nicholas J. Lynch, Wilhelm J. Schwaeble, Misao Matsushita, Masaru Okabe, Teizo Fujita

JOURNAL OF IMMUNOLOGY, 177(12) 8626-8632, Dec, 2006
Identification and functional characterization of a presqualene diphosphate phosphatase

K Fukunaga, M Arita, M Takahashi, AJ Morris, M Pfeffer, BD Levy

JOURNAL OF BIOLOGICAL CHEMISTRY, 281(14) 9490-9497, Apr, 2006
Identification and functional characterization of a presqualene diphosphate phosphatase

K Fukunaga, M Arita, M Takahashi, AJ Morris, M Pfeffer, BD Levy

JOURNAL OF BIOLOGICAL CHEMISTRY, 281(14) 9490-9497, Apr, 2006

Books and Other Publications

補体への招待

株式会社メジカルビュー社, 2011 (ISBN: 9784758300384)

Presentations

MASP1/3欠損マウスにおける形態異常-3MC症候群との関連

第49回補体シンポジウム, 2012
MASP-3のin vivo補体第二経路活性化における役割

第49回補体シンポジウム, 2012
MASP1遺伝子産物の多機能性について

第48回補体シンポジウム, 2011
MBL/MASP-1 complexes efficiently cleave a zymogen of complement factor D.

23th International Complement Workshop, 2010
補体D因子前駆体を活性化するMASP-1/3複合体の解析

第47回補体シンポジウム, 2010
MBL/MASP-1 complexes efficiently cleave a zymogen of complement factor D.

23th International Complement Workshop, 2010
補体 D 因子前駆体を認識する抗体の作製とそれを用いた解析

第 46 回補体シンポジウム, 2009
MASP1/3欠損マウスにおける補体第二経路の異常

自然免疫の最前線-３学会合同大会２００８-, 2008
MASP-1による補体第二経路のD因子の活性化

自然免疫の最前線-３学会合同大会２００８-, 2008
MASP1/3 knockout mouse lacks the alternative pathway activation due to deficiency of factor D activation

22th International Complement Workshop, 2008
Activation of mannose binding lectin-associated serine protease 3

22th International Complement Workshop, 2008
A novel role of MASP-1 to activate the alternative complement pathway

日本免疫学会総会・学術集会, 2008
A novel role of MASP-1 to activate the alternative complement pathway

日本免疫学会総会・学術集会, 2008
Mannose-binding lectin-associated serine protease 3 (MASP-3)の機能解析

BMB2008, 2008
MASP1/3 knockout mouse lacks the alternative pathway activation due to deficiency of factor D activation

22th International Complement Workshop, 2008
Activation of mannose binding lectin-associated serine protease 3

22th International Complement Workshop, 2008
A novel role of MASP-1 to activate the alternative complement pathway

2008
A novel role of MASP-1 to activate the alternative complement pathway

2008
Two routes (MASP-1 and MASP-2 routes) are present to activate the lectin complement pathway

21th International Complement Workshop, 2006
Two routes (MASP-1 and MASP-2 routes) are present to activate the lectin complement pathway

21th International Complement Workshop, 2006

Profile Information

Research Interests

Research Areas

Research History

Committee Memberships

Awards

Misc.

Books and Other Publications

Presentations

Professional Memberships

Research Projects

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