NAKANISHI Toyofumi

J-GLOBAL         Last updated: Apr 12, 2019 at 13:45
 
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Name
NAKANISHI Toyofumi
E-mail
nakanisiosaka-med.ac.jp
Affiliation
Osaka Medical College
Section
Faculty of Medicine
Degree
Ph.D

Research Interests

 
 

Research Areas

 
 

Education

 
 
 - 
1980
Faculty of Pharmaceutical Science, Osaka University of Pharmaceutical Sciences
 

Awards & Honors

 
Sep 2017
Matsumoto's Prize, Japanese Society of Biomedical Mass Spectrometry
 

Published Papers

 
Shiono K, Hashizaki R, Nakanishi T, Sakai T, Yamamoto T, Ogata K, Harada KI, Ohtani H, Katano H, Taira S
Journal of agricultural and food chemistry   65(35) 7624-7628   Sep 2017   [Refereed]
Kamata T, Shima N, Keiko Sasaki, Matsuta S, Takei S, Katagi M, Miki A, Zaitsu K, Nakanishi T, Sato T, Suzuki, K and Tsuchihashi H.
Anal. Chem.   87(11) 5476-5481   Jun 2015   [Refereed]
Suwa Yoshifumi, Nakanishi Toyofumi, Kato-Kogoe Nahoko, Kimura Yoshihiro, Terai Haruhiko, Nakajima Yoichiro, Sunano Akihiro, Yamamoto Kayoko, Ueno Takaaki
JOURNAL OF HARD TISSUE BIOLOGY   26(1) 33-36   Jan 2017   [Refereed]
[Rapid Identification of Infectious Microorganisms in Clinical Samples by MALDI-TOF MS Analysis].
Nakanishi T
Rinsho byori. The Japanese journal of clinical pathology   63(4) 465-471   Apr 2015   [Refereed]
Significance of the vascular concentration of angiotensin II receptor blockers on the lowering mechanism of blood pressure in spontaneously hypertensive rats
Takai Shinji, Jin Denan, Sakonjo Hiroshi, Takubo Takayuki, Nakanishi Toyofumi
JOURNAL OF PHARMACOLOGICAL SCIENCES   124 220P   2014   [Refereed]
Takai S, Jin D, Sakonjo H, Takubo T, Nakanishi T
Journal of pharmacological sciences   123(4) 371-379   Nov 2013   [Refereed]
Ooi Y, Shiba H, Nagai K, Higashiyama T, Nakanishi T, Nakano T, Ukimura A, Gonoi T
Internal medicine (Tokyo, Japan)   53(18) 2111-2113   2014   [Refereed]
Shima Noriaki, Sasaki Keiko, Kamata Tooru, Matsuta Shuntaro, Katagi Munehiro, Miki Akihiro, Zaitsu Kei, Sato Takako, Nakanishi Toyofumi, Tsuchihashi Hitoshi, Suzuki Koichi
FORENSIC TOXICOLOGY   33(1) 122-130   Jan 2015   [Refereed]
Nakanishi T, Ito M, Nirasawa T, Tsuji M, Takubo T
Clinical biochemistry   46(15) 1595-1600   May 2013   [Refereed]
The effect of periocularly administered candesartan-PLGA microparticles on diabetes-induced retinal inflammatory damage
Fukumoto Masanori, Takai Shinji, Nakanishi Toyofumi, Horie Taeko, Morishita Seita, Oku Hidehiro, Ikeda Tsunehiko
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE   55(13)    Apr 2014   [Refereed]
Nakanishi T, Setou M, Kuhara T
Analytical and bioanalytical chemistry   403(7) 1775-1776   Jun 2012   [Refereed]
Bouras G, Nakanishi T, Fujita Y, Tsunemi S, Takubo T, Tanigawa N
Analytical and bioanalytical chemistry   403(7) 1801-1809   Jun 2012   [Refereed]
Miki A, Katagi M, Kamata T, Zaitsu K, Tatsuno M, Nakanishi T, Tsuchihashi H, Takubo T, Suzuki K
Journal of mass spectrometry : JMS   46(4) 411-416   Apr 2011   [Refereed]
Nakanishi T, Takai S, Jin D, Takubo T
Mass spectrometry (Tokyo, Japan)   2(1) A0021   2013   [Refereed]
Nakanishi T, Yoshioka M, Moriuchi K, Yamamoto D, Tsuji M, Takubo T
Biochimica et biophysica acta   1804(7) 1449-1456   Jul 2010   [Refereed]
[Clinical applications of MALDI imaging using sliced sections of formalin-fixed paraffin-embedded tissues and longitudinal sliced hairs].
Nakanishi T, Ito M, Ueda K, Wada S, Fujioka S, Tsuji M, Takubo T
Rinsho byori. The Japanese journal of clinical pathology   60(2) 125-130   Feb 2012   [Refereed]
Miki Akihiro, Katagi Munehiro, Shima Noriaki, Kamata Hiroe, Tatsuno Michiaki, Nakanishi Toyofumi, Tsuchihashi Hitoshi, Takubo Takayuki, Suzuki Koichi
FORENSIC TOXICOLOGY   29(2) 111-116   Jul 2011   [Refereed]
Hiura Y, Nakanishi T, Tanioka M, Takubo T, Moriwaki S
Japanese clinical medicine   2 35-41   2011   [Refereed]
Tsunemi Soichiro, Nakanishi Toyofumi, Fujita Yoshihisa, Bouras George, Miyamoto Yoshiharu, Miyamoto Akiko, Nomura Eiji, Takubo Takayuki, Tanigawa Nobuhiko
ONCOLOGY REPORTS   23(4) 949-956   Apr 2010   [Refereed]
[Proteomic analysis of changes in the serum protein profile by anti-TNF-alpha therapy].
Takeuchi T, Kotani T, Nakanishi T, Tabushi-Matsumura Y, Takubo T, Makino S
Rinsho byori. The Japanese journal of clinical pathology   58(4) 332-336   Apr 2010   [Refereed]
Tsunemi S, Nakanishi T, Fujita Y, Bouras G, Miyamoto Y, Miyamoto A, Nomura E, Takubo T, Tanigawa N
Oncology reports   23(4) 949-956   Apr 2010   [Refereed]
Tabushi Y, Nakanishi T, Takeuchi T, Nakajima M, Ueda K, Kotani T, Makino S, Shimizu A, Hanafusa T, Takubo T
Annals of clinical biochemistry   45(4) 413-417   Jul 2008   [Refereed]
Nakanishi Toyofumi
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES   870(2) 146-147   Jul 2008   [Refereed]
[Oxidative precipitation of transthyretin--a clue to elucidate amyloidosis].
Yoshioka M, Nakanishi T
Rinsho byori. The Japanese journal of clinical pathology   56(5) 425-431   May 2008   [Refereed]
Fujita Y, Nakanishi T, Miyamoto Y, Hiramatsu M, Mabuchi H, Miyamoto A, Shimizu A, Takubo T, Tanigawa N
Cancer letters   263(2) 280-290   May 2008   [Refereed]
Ueda K, Nakanishi T, Shimizu A, Takubo T, Matsuura N
Annals of clinical biochemistry   45(Pt 1) 65-69   Jan 2008   [Refereed]
Takeuchi T, Nakanishi T, Tabushi Y, Hata A, Shoda T, Kotani T, Shimizu A, Takubo T, Makino S, Hanafusa T
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences   855(1) 66-70   Aug 2007   [Refereed]
Fujita Y, Nakanishi T, Hiramatsu M, Mabuchi H, Miyamoto Y, Miyamoto A, Shimizu A, Tanigawa N
Clinical cancer research : an official journal of the American Association for Cancer Research   12(21) 6415-6420   Nov 2006   [Refereed]
Shimizu A, Nakanishi T, Miyazaki A
Mass spectrometry reviews   25(5) 686-712   Sep 2006   [Refereed]
Nakanishi T, Takeuchi T, Ueda K, Murao H, Shimizu A
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences   838(1) 15-20   Jun 2006   [Refereed]
Miyazaki A, Nakanishi T, Shimizu A, Mizobuchi M, Yamada Y, Imai K
Hemoglobin   29(1) 1-10   2005   [Refereed]
Iguchi K, Nakanishi T, Miyazaki A, Shimizu A, Ota A
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences   806(1) 25-31   Jun 2004   [Refereed]
Nakanishi T, Sato T, Sakoda S, Yoshioka M, Shimizu A
Biochimica et biophysica acta   1698(1) 45-53   Apr 2004   [Refereed]
Sato T, Yamamoto Y, Nakanishi T, Fukada K, Sugai F, Zhou Z, Okuno T, Nagano S, Hirata S, Shimizu A, Sakoda S
Journal of the neurological sciences   218(1-2) 79-83   Mar 2004   [Refereed]
Sass JO, Nakanishi T, Sato T, Shimizu A
Annals of clinical biochemistry   41(Pt 2) 157-159   Mar 2004   [Refereed]
Miyazaki A, Nakanishi T, Shimizu A, Ninomiya K, Nishimura S, Imai K
Hemoglobin   27(4) 243-247   Nov 2003   [Refereed]
Kondo F, Saito H, Hayashi R, Onda H, Kobayashi S, Matsumoto M, Suzuki M, Ito Y, Oka H, Nakanishi T, Shimizu A
The Analyst   128(11) 1360-1364   Nov 2003   [Refereed]
Sass JO, Nakanishi T, Sato T, Sperl W, Shimizu A
Biochemical and biophysical research communications   310(1) 242-246   Oct 2003   [Refereed]
Koyama R, Nakanishi T, Ikeda T, Shimizu A
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences   792(1) 5-21   Jul 2003   [Refereed]
[A variant hemoglobin found by dissociation of blood glucose from HbA1c on routine physical examination].
Ogawa K, Bando T, Ogawa M, Miyazaki A, Nakanishi T, Shimizu A
Rinsho byori. The Japanese journal of clinical pathology   51(6) 508-515   Jun 2003   [Refereed]
Kishikawa M, Sass JO, Sakura N, Nakanishi T, Shimizu A, Yoshioka M
Biochimica et biophysica acta   1588(2) 135-138   Nov 2002   [Refereed]
Nakanishi T, Miyazaki A, Shimizu A, Yamaguchi A, Nishimura S
Clinica chimica acta; international journal of clinical chemistry   323(1-2) 89-101   Sep 2002   [Refereed]
Shimizu A, Nakanishi T, Kishikawa M, Miyazaki A
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences   776(1) 15-30   Aug 2002   [Refereed]
Nakanishi T, Koyama R, Ikeda T, Shimizu A
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences   776(1) 89-100   Aug 2002   [Refereed]

Misc

 
Simple and defined method to detect the SOD-1 mutants from patients with familial amyotrophic lateral selerosis by mass spectrometry
J Nerosci. Methods   81(1) 23-35   1998
Research and Development Center

Association Memberships

 
 

Research Grants & Projects

 
Identifications of pancreatic cancer specific neo-antigens with the autoantibodiomics and verifications of diagnostic utilities of its autoantibody screening to neo-antigens
Project Year: Apr 2019 - Mar 2021    Investigator(s): NAKANISHI Toyofumi
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(C))
Project Year: 2007 - 2008    Investigator(s): Toyofumi NAKANISHI
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(C))
Project Year: 2005 - 2006    Investigator(s): Toyofumi NAKANISHI
At 2001, Prof. Hanash and his colleagues first reported that the autoantibodies against Annexin-I & II frequently (37-40%) were existed in plasma of lung adenocarcinoma using proteomics-based analysis. Thereafter many researchers have been identif...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(C))
Project Year: 2004 - 2005    Investigator(s): Akira SHIMIZU
During the process of transthyretin (TTR) analysis, we found unique modified forms of TTR ; those are S-sulfo-TTR and TTR with the substitution of cysteine at position 10 by glycine. To clarify the generation process of these unique derivatives in...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(C))
Project Year: 2002 - 2003    Investigator(s): Akira SHIMIZU
Cysteine and cystine in protein are modified to various derivatives in vitro and in vivo. By electrospray ionization mass spectrometry (ESI-MS), we found derivatives of serum transthyretin (TTR) in which cysteine residue at position 10 was changed...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(C))
Project Year: 2002 - 2003    Investigator(s): Toyofumi NAKANISHI
A catalogue of proteins in the human vitreous humor may contribute to elucidating the pathogenesis of various diseases in ophthalmology. To improve the recovery of proteins in vitreous, we applied one-dimensional sodium dodecyl sulfate-polyacrylam...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(C))
Project Year: 1999 - 2001    Investigator(s): Toyofumi NAKANISHI
We applied nano-electrospray ionization mass spectrometry (NanoESIMS) for the quantification of the rations between apo to holo types of metalloproteins (copper/zinc binding superoxide dismutase:SOD-1, metallothioneine) to clarify the etiology of ...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(B))
Project Year: 1997 - 2000    Investigator(s): Akira SHIMIZU
We established a reference method for glyco-haemoglobin (HbAlc), which is a most popular index for control of diabetes mellitus. The N-terminal residues of the Hb β-chains, which are released by enzymatic cleavage of the intact Hb molecule with en...

Patents

 
特願2012-198042 : Analysis of bioactive molecules in hair by MALDI-imaging
NAKANISHI Toyofumi