2022年5月14日
A Case of Bing-Neel Syndrome Successfully Treated with Tirabrutinib.
Internal medicine (Tokyo, Japan)
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- 巻
- 61
- 号
- 23
- 開始ページ
- 3575
- 終了ページ
- 3579
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.2169/internalmedicine.9545-22
Bing-Neel syndrome (BNS) is a rare central nervous system manifestation of lymphoplasmacytic lymphoma/Waldenström macroglobulinemia (LPL/WM). We herein report a 62-year-old man with LPL/WM after multiple chemotherapies. He had weakness of lower extremities and elevated serum IgM levels. A bone marrow examination showed lymphoplasmacytic cells infiltration. Contrast-enhanced magnetic resonance imaging suggested enhancing lesions in the cauda equina roots. He was diagnosed with BNS and started on treatment with tirabrutinib 480 mg daily. Within three months, he showed clinical and radiologic improvement. Tirabrutinib may have utility as an effective treatment for BNS.
- リンク情報
- ID情報
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- DOI : 10.2169/internalmedicine.9545-22
- PubMed ID : 35569989
- PubMed Central 記事ID : PMC9790791