ADACHI-AKAHANE Satomi

J-GLOBAL         Last updated: Jan 16, 2020 at 21:33
 
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Name
ADACHI-AKAHANE Satomi
Affiliation
Toho University
Section
Faculty of Medicine, School of Medicine
Job title
Satomi Adachi-Akahane
Degree
Doctor of Phylosophy(Pharmaceutical Sciences)(The University of Tokyo), Doctor of Phylosophy(Pharmaceutical Sciences)(The University of Tokyo)

Research Areas

 
 

Academic & Professional Experience

 
Apr 2013
 - 
Today
Professor, Department of Physiology, School of Medicine
 
2007
 - 
Today
Associate professor, Department of Pharmacology,Faculty of Medicine, Graduate School of Medicine,Toho University
 
2005
 - 
2007
Assistant professor, Department of Pharmacology,Faculty of Medicine,Graduate School of Medicine,Toho University
 
1986
 - 
1992
Research Assistant, University of Tokyo, Faculty of Pharmaceutical Sciences
 
1992
 - 
1998
Assistant Professor, University of Tokyo, Faculty of Pharmaceutical Sciences
 
1998
 - 
2005
Assistant Professor, University of Tokyo, Graduate School of Pharmaceutical Sciences
 

Education

 
 
 - 
1986
Biopharmaceutics Pharmacology, Graduate School, Division of Pharmaceutical Sciences, The University of Tokyo
 
 
 - 
1985
Faculty of Pharmaceutical Science, The University of Tokyo
 

Published Papers

 
Oda S, Funato H, Sato F, Adachi-Akahane S, Ito M, Takase K, Kuroda M
The Journal of comparative neurology   522 2089-2106   Jun 2014   [Refereed]
Kitahara K, Nakamura Y, Tsuneoka Y, Adachi-Akahane S, Tanaka H, Yamazaki H, Takahara A, Yamazaki J, Ikeda T, Sugiyama A
Cardiovascular toxicology   13 234-243   Sep 2013   [Refereed]
Ito M, Yamanashi Y, Toyoda Y, Izumi-Nakaseko H, Oda S, Sugiyama A, Kuroda M, Suzuki H, Takada T, Adachi-Akahane S
Biochimica et biophysica acta   (2) 459-468   Feb 2013   [Refereed]
Ito M, Adachi-Akahane S
Journal of pharmacological sciences   123 312-317   2013   [Refereed]

Misc

 
Medousa and Carcium Channel
ADACHI-AKAHANE Satomi
J.Med.Soc.Toho   61(1) 68-69   Jan 2014
伊藤雅方, 山梨義英, 豊田優, 中瀬古寛子, 杉山篤, 鈴木洋史, 高田龍平, 赤羽悟美
日本薬理学会関東部会口演要旨集   126th 57   2012
伊藤雅方, 中瀬古寛子, 杉山篤, 赤羽悟美
日本分子生物学会年会プログラム・要旨集(Web)   35th WEB ONLY 3P-0707   2012
小原浩, 小原浩, 本川佳幸, 中村裕二, 北原健, 北原健, 山崎有希子, 山崎有希子, 原田拓真, 矢來幸弘, 赤羽悟美, 池田隆徳, 山崎純一, 杉山篤
日本薬理学会関東部会口演要旨集   127th 49   2012
赤羽悟美, 坂倉智子, 伊藤雅方, 中瀬古寛子
日本薬理学会関東部会口演要旨集   122nd 38   2010
伊藤雅方, 中瀬古寛子, 丸山博子, 杉山篤, 赤羽悟美
生化学   ROMBUNNO.1P-0021   2010
伊藤雅方, 中瀬古寛子, 水流弘道, 赤羽悟美
日本分子生物学会年会講演要旨集   32nd(Vol.4) 60   2009
55(1) 41-44   Jan 2008
Teng Jinfeng, Iida Kazuko, Tada Tomoko, Saka Ayaka, Tamai Masumi, Izumi-Nakaseko Hiroko, Adachi-Akahane Satomi, Iida Hidetoshi
Biophysics   47(1)    Nov 2007
68(1) 20-21   Jan 2006
ADACHI AKAHANE Satomi
Folia Pharmacologica Japonica   123(3) 197-209   Mar 2004
The voltage-dependent L-type Ca2+ channel plays a key role in the spacial and temporal regulation of Ca2+. In cardiac excitation-contraction coupling, Ca2+-induced Ca2+ release (CICR) from ryanodine receptors (RyRs), triggered by Ca2+ entry throug...
KUROSE Hitoshi, TAKIKAWA Emiko, AKAHANE Satomi, TANAKA Rie, NAGAO Taku
Folia Pharmacologica Japonica   112 68P-72P   Oct 1998
G protein-coupled receptor kinases (GRKs) are believed to involve in desensitization of the G protein-coupled receptors. So far, cDNAs of six GRKs were cloned from several species including human and rat. However, it is unknown whether single GRK ...
KUSAYAMA Toshiyuki, OKA Junichiro, YABANA Hideo, ADACHI-AKAHANE Satomi, NAGAO Taku
Biological & pharmaceutical bulletin   17(8) 1023-1028   Aug 1994
The affinities for β-adrenoceptors, the subtype-selectivity and the agonistic effectiveness of T-0509 (a catechol derivative of denopamine) and colterol (N-tert-butylnoradrenaline ; Col) were compared with those of other β-agonists using a binding...
IMAI Kazuhiro, HIGASHIDATE Sakae, PRADOS PabloRuano, SANTA Tomofumi, AKACHIAKAHANE Satomi, NAGAO Taku
Biological & pharmaceutical bulletin   17(7) 907-910   Jul 1994
Three types of calcium antagonists, diltiazem, verapamil and nicardipine, were separately infused into Sprague-Dawley (SD) rats (under pentobarbital anesthesia n=5) through the left femoral vein at four different flow rates. Mean arterial blood pr...
Calcium-dependent dynamic changes in the subcellular distribution of calmodulin in frog spinal cells
Brain Research   487(1) 196   1989
Electrophysiological and pharmacological properties of single spinal neurons isolated from adult bullfrogs
Comparative Biochemistry & Physiology, C : Comparative Pharmacology & Toxicology   95(2) 253   1990
Activation of beta-adrenergic neceptor induces Na+-dependent inward currents in acutely dissociated motoneurons of bullfrog spinal cord
Brain Research   571(1) 79   1992
Cyclic AMP analog activates Na+-dependent inward currents in dissociated frog motoneurons
Brain Research   573(2) 349   1992
Satomi Adachi-Akahane, Yukiko Amano, Ryo Okuyama, Taku Nagao
Japanese Journal of Pharmacology   61(3) 263-266   1993

Books etc

 
Ca2+ antagonists and agonists.
Handbook of Experimental Pharmacology : Pharmacology of Ionic Channel Function, Activators and Inhibitors. Springer   2000   

Research Grants & Projects

 
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(C))
Project Year: 2006 - 2007    Investigator(s): Satomi AKAHANE
Recent studies have shown that the impairment of L-type Ca^<2+> channel function is associated with arrhythmia such as atrial fibrillation. Aiming at clarifying the signaling molecular complex involved in the regulation of L-type Ca^<2+> channel i...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(C))
Project Year: 2004 - 2005
L-type Ca^<2+> channel serves as a primary step in the regulation of Ca^<2+> signaling. In this project, we aimed at clarifying the molecular mechanism underlying the gating regulation of L-type Ca^<2+> channel α_<1C> subunit (Ca_v1.2) through the...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(C))
Project Year: 2001 - 2003    Investigator(s): Satomi AKAHANE
The voltage-dependent L-type Ca^<2+> channel plays a key role in the spatial and temporal regulation of Ca^<2+>. In cardiac excitation-contraction coupling, Ca2 tinduced Ca^<2+> release (CICR) from ryanodine receptors (RyRs), triggered by Ca^<2+> ...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(A))
Project Year: 2001 - 2002    Investigator(s): Taku NAGAO
1) Treatment with H_2O_2 activates G_I/G_o in rat neonatal ventricular myocytes. We found that H_2O_2 modifies Cys^<287> and Cys^<326> of G_<αi>. Angiotensin II stimulation generated ROS and induced the activation of MAP kinase. The elimination of...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(A))
Project Year: 1998 - 2000    Investigator(s): Taku NAGAO
The aim of this project was to open up a novel concept for therapeutic basis of heart failure. In the past three years from 1998 through 2000, we have carried out the research project by focusing on Ca^<2+> signaling in cardiac E-C coupling at the...

Conference Activities & Talks

 
赤羽悟美
日本性機能学会雑誌   30 Jun 2010